ICAM3 (NM_002162) Human Untagged Clone

SKU SC128181

ICAM3 (untagged)-Human intercellular adhesion molecule 3 (ICAM3)

Product Data

• Type: Human Untagged Clone
• Target Symbol: ICAM3
• Synonyms: CD50; CDW50; ICAM-R
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC128181 sequence for NM_002162 edited (data generated by NextGen Sequencing); ATGGCCACCATGGTACCATCCGTGTTGTGGCCCAGGGCCTGCTGGACTCTGCTGGTCTGC; TGTCTGCTGACCCCAGGTGTCCAGGGGCAGGAGTTCCTTTTGCGGGTGGAGCCCCAGAAC; CCTGTGCTCTCTGCTGGAGGGTCCCTGTTTGTGAACTGCAGTACTGATTGTCCCAGCTCT; GAGAAAATCGCCTTGGAGACGTCCCTATCAAAGGAGCTGGTGGCCAGTGGCATGGGCTGG; GCAGCCTTCAATCTCAGCAACGTGACTGGCAACAGTCGGATCCTCTGCTCAGTGTACTGC; AATGGCTCCCAGATAACAGGCTCCTCTAACATCACCGTGTACAGGCTCCCGGAGCGTGTG; GAGCTGGCACCCCTGCCTCCTTGGCAGCCGGTGGGCCAGAACTTCACCCTGCGCTGCCAA; GTGGAGGATGGGTCGCCCCGGACCAGCCTCACGGTGGTGCTGCTTCGCTGGGAGGAGGAG; CTGAGCCGGCAGCCCGCAGTGGAGGAGCCAGCGGAGGTCACTGCCACTGTGCTGGCCAGC; AGAGACGACCACGGAGCCCCTTTCTCATGCCGCACAGAACTGGACATGCAGCCCCAGGGG; CTGGGACTGTTCGTGAACACCTCAGCCCCCCGCCAGCTCCGAACCTTTGTCCTGCCCGTG; ACCCCCCCGCGCCTCGTGGCCCCCCGGTTCTTGGAGGTGGAAACGTCGTGGCCGGTGGAC; TGCACCCTAGACGGGCTTTTTCCAGCCTCAGAGGCCCAGGTCTACCTGGCGCTGGGGGAC; CAGATGCTGAATGCGACAGTCATGAACCACGGGGACACGCTAACGGCCACAGCCACAGCC; ACGGCGCGCGCGGATCAGGAGGGTGCCCGGGAGATCGTCTGCAACGTGACCCTAGGGGGC; GAGAGACGGGAGGCCCGGGAGAACTTGACGGTCTTTAGCTTCCTAGGACCCATTGTGAAC; CTCAGCGAGCCCACCGCCCATGAGGGGTCCACAGTGACCGTGAGTTGCATGGCTGGGGCT; CGAGTCCAGGTCACGCTGGACGGAGTTCCGGCCGCGGCCCCGGGGCAGCCAGCTCAACTT; CAGCTAAATGCTACCGAGAGTGACGACGGACGCAGCTTCTTCTGCAGTGCCACTCTCGAG; GTGGACGGCGAGTTCTTGCACAGGAACAGTAGCGTCCAGCTGCGAGTCCTGTATGGTCCC; AAAATTGACCGAGCCACATGCCCCCAGCACTTGAAATGGAAAGATAAAACGAGACACGTC; CTGCAGTGCCAAGCCAGGGGCAACCCGTACCCCGAGCTGCGGTGTTTGAAGGAAGGCTCC; AGCCGGGAGGTGCCGGTGGGGATCCCGTTCTTCGTCAACGTAACACATAATGGTACTTAT; CAGTGCCAAGCGTCCAGCTCACGAGGCAAATACACCCTGGTCGTGGTGATGGACATTGAG; GCTGGGAGCTCCCACTTTGTCCCCGTCTTCGTGGCGGTGTTACTGACCCTGGGCGTGGTG; ACTATCGTACTGGCCTTAATGTACGTCTTCAGGGAGCACCAACGGAGCGGCAGTTACCAT; GTTAGGGAGGAGAGCACCTATCTGCCCCTCACGTCTATGCAGCCGACAGAAGCAATGGGG; GAAGAACCGTCCAGAGCTGAGTGA; ; Clone variation with respect to NM_002162.3; 309 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002162 unedited; GATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCACCTTCCTCT; GTCAGAATGGCCACCATGGTACCATCCGTGTTGTGGCCCAGGGCCTGCTGGACTCTGCTG; GTCTGCTGTCTGCTGACCCCAGGTGTCCAGGGGCAGGAGTTCCTTTTGCGGGTGGAGCCC; CAGAACCCTGTGCTCTCTGCTGGAGGGTCCCTGTTTGTGAACTGCAGTACTGATTGTCCC; AGCTCTGAGAAAATCGCCTTGGAGACGTCCCTATCAAAGGAGCTGGTGGCCAGTGGCATG; GGCTGGGCAGCCTTCAATCTCAGCAACGTGACTGGCAACAGTCGGATCCTCTGCTCAGTG; TACTGCAATGGCTCCCAGATAACAGGCTCCTCTAACATCACCGTGTACAGGCTCCCGGAG; CGTGTGGAGCTGGCACCCCTGCCTCCTTGGCAGCCGGTGGGCCAGAACTTCACCCTGCGC; TGCCAAGTGGAGGATGGGTCGCCCCGGACCAGCCTCACGGTGGTGCTGTTTCGCTGGGAG; GAGGAGCTGAGCCGGCAGCCCGCAGTGGAGGAGCCAGCGGAGGTCACTGCCACTGTGCTG; GCCAGCAGAGACGACCACGGAGCCCCTTTCTCATGCCGCACAGAACTGGACATGCAGCCC; CAGGGGCTGGGACTGTTCGTGACACCCTCAGCCCCCCGCCAGCTCCGAACCTTTGTCCTG; CCCCGTGACCCCCCGCGCCTCGTGGCCCCCCGGNTCTTGGAGGTGGAAACGTCGTGGCCG; GTGGACTGCACCCTANACGGGGCTTTCTCGCCTCAGAGCCCAGTTCTACCTGCGCTGNGG; GACAGATGCTGATGCGACAGTCATGACCCACGGGACACGCTACGGGCCAGNCCAGCCACG; CGCGCGCGATAAGAGGTGCCCGGAGATCGCTGCACGGACCTAGGGCNAAAACACGGAGCC; CGGAGACCTGACGTT;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002162 unedited; TAGCTTGNNACCGCGGCCGCATNCTANGATCGAGTTTTTTTTTTTTTTTTTTAGGGAGTT; TGAAGGCTTTATTGGTGCGGAATCTGAGGGCACAGCCAAGCCCCCGCCAACTTTGATCCC; GGATCCCAGCGTCACTCAGCTCTGGACGGTTCTTCCCCCATTGCTTCTGTCGGCTGCATA; GACGTGAGGGGCAGATAGGTGCTCTCCTCCCTAACATGGTAACTGCCGCTCCGTTGGTGC; TCCCTGAAGACGTACATTAAGGCCAGTACGATAGTCACCACGCCCAGGGTCAGTAACACC; GCCACGAAGACGGGGACAAAGTGGGAGCTCCCAGCCTCAATGTCCATCACCACGACCAGG; GTGTATTTGCCTCGTGAGCTGGACGCTTGGCACTGATAAGTACCATTATGTGTTACGTTG; ACGAAGAACGGGATCCCCACCGGCACCTCCCGGCTGGAGCCTTCCTTCAAACACCGCAGC; TCGGGGTACGGGTTGCCCCTGGCTTGGCACTGCAGGACGTGTCTCGTTTTATCTTTCCAT; TTCAAGTGCTGGGGGCATGTGGCTCGGTCAATTTTGGGACCATACAGGACTCGCAGCTGG; ACGCTACTGTTCCTGTGCAAGAACTCGCCGTCCACCTCGAGAGTGGCACTGCAGAAGAAG; CTGCGTCCGTCGTCACTCTCGGTAGCATTTAGCTGAAATTGAGCTGGCTGCCCCGGGCCG; CGGCCGGGACTCCGTCCAGCGTGACCTGGACTCGAGCCCCAGCCATGCAACTCACGGTCA; CTGTGGACCCCTCATGGGCGGTGGGCTCGCTGAGGTTTCACAATGGTCCTAGGAAACC;
• Restriction Sites: NotI-NotI
• ACCN: NM_002162
• Insert Size: 1900 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_002162.2, NP_002153.1
• RefSeq Size: 1824 bp
• RefSeq ORF: 1644 bp
• Locus ID: 3385
• UniProt ID: P32942
• Cytogenetics: 19p13.2
• Domains: ICAM_N, ig, IG
• Protein Families: ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)
• Summary: The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]; Transcript Variant: This variant (1) encodes the longest isoform (1).