BCAS3 (NM_017679) Human Untagged Clone

CAT#: SC126955

BCAS3 (untagged)-Human breast carcinoma amplified sequence 3 (BCAS3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: BCAS3
• Synonyms: GAOB1; MAAB
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC126955 sequence for NM_017679 edited (data generated by NextGen Sequencing)
  ATGAATGAAGCTATGGCTACAGATTCCCCAAGAAGACCCAGTCGTTGTACTGGTGGAGTT
  GTGGTTCGCCCCCAGGCTGTCACAGAGCAGTCCTACATGGAAAGTGTTGTGACTTTTCTG
  CAGGATGTTGTGCCACAGGCTTACAGTGGAACACCTCTAACAGAAGAAAAGGAGAAAATA
  GTCTGGGTCAGATTTGAAAATGCAGATTTAAATGATACATCAAGAAATCTGGAATTTCAT
  GAAATACATAGTACTGGGAGTGAACCGCCTTTGTTGATTATGATTGGCTACAGTGATGGA
  ATGCAGGTCTGGAGCATCCCTATCAGTGGCGAAGCACAAGAGCTCTTCTCTGTTCGACAT
  GGCCCAATTCGAGCGGCTAGAATCTTGCCTGCTCCACAGTTTGGTGCTCAAAAATGTGAT
  AACTTTGCTGAAAAAAGACCCCTCCTTGGTGTTTGTAAGAGCATTGGATCTTCTGGCACA
  AGCCCACCGTACTGTTGTGTGGATCTGTATTCACTTCGTACTGGGGAGATGGTCAAGTCC
  ATTCAATTTAAGACACCTATTTATGATCTCCATTGCAATAAACGGATCCTTGTCGTAGTC
  TTGCAGGAGAAAATTGCTGCCTTTGATAGCTGTACTTTCACGAAGAAATTCTTTGTTACA
  AGCTGCTATCCATGTCCAGGGCCAAACATGAATCCTATTGCTCTTGGGAGCCGCTGGCTT
  GCTTATGCAGAAAACAAGTTGATTCGATGTCATCAGTCCCGTGGTGGAGCCTGTGGAGAC
  AACATTCAGTCTTATACTGCCACAGTCATTAGTGCTGCTAAAACATTGAAAAGTGGCCTG
  ACAATGGTAGGGAAAGTGGTGACTCAGCTGACAGGCACACTGCCTTCAGGTGTGACAGAA
  GATGATGTTGCCATCCACAGTAATTCACGGCGGAGTCCTTTGGTCCCAGGCATCATCACA
  GTTATTGACACCGAAACCGTTGGAGAGGGCCAGGTGCTTGTGAGTGAGGATTCTGACAGT
  GATGGCATTGTGGCCCACTTCCCTGCCCATGAGAAGCCAGTGTGCTGCATGGCTTTTAAT
  ACAAGTGGAATGCTTCTAGTCACAACAGACACCCTTGGCCATGACTTTCATGTCTTCCAA
  ATTCTGACTCATCCTTGGTCCTCATCACAATGTGCTGTCCACCATCTGTATACTCTTCAC
  AGGGGAGAAACTGAAGCCAAAGTACAGGACATCTGCTTCAGCCATGACTGTCGCTGGGTT
  GTGGTCAGTACTCTCCGGGGTACTTCCCACGTTTTCCCCATCAACCCTTATGGTGGCCAG
  CCTTGTGTTCGTACACATATGTCACCACGAGTAGTGAATCGCATGAGCCGTTTCCAGAAA
  AGTGCTGGACTGGAAGAGATTGAACAAGAACTGACGTCTAAGCAAGGAGGTCGCTGTAGC
  CCTGTTCCAGGTCTATCAAGCAGCCCTTCTGGGTCACCCTTGCATGGGAAACTGAACAGC
  CAAGACTCCTATAACAATTTTACCAACAACAACCCTGGCAACCCTCGGCTCTCTCCTCTT
  CCCAGCTTGATGGTAGTGATGCCTCTTGCACAAATCAAGCAGCCAATGACATTGGGGACC
  ATCACCAAACGAACCGGCAAAGTTAAACCTCCTCCACAAATTTCACCCAGCAAATCGATG
  GGCGGAGAATTTTGTGTGGCTGCTATCTTCGGAACATCCAGGTCATGGTTTGCAAATAAT
  GCAGGTCTGAAAAGAGAAAAAGATCAGTCCAAACAAGTTGTAGTTGAGTCCCTGTACATT
  ATCAGTTGCTATGGCACCTTAGTGGAACACATGATGGAGCCGCGACCCCTCAGCACTGCA
  CCCAAGATTAGTGACGACACACCACTGGAAATGATGACATCGCCTCGAGCCAGCTGGACT
  CTGGTTAGAACCCCTCAATGGAATGAATTGCAGCCACCGTTTAATGCAAACCACCCTCTG
  CTCCTCGCTGCAGATGCAGTACAGTATTATCAGTTCCTGCTTGCTGGCCTGGTTCCCCCT
  GGAAGTCCTGGGCCCATTACTCGACATGGGTCTTACGACAGTTTAGCTTCTGACCATAGT
  GGACAGGAAGATGAAGAATGGCTTTCCCAGGTTGAAATTGTAACACACACTGGACCCCAT
  AGACGTCTGTGGATGGGTCCACAGTTCCAGTTCAAAACCATCCATCCCTCAGGCCAAACC
  ACAGTTATCTCATCCAGTTCATCTGTGTTGCAGTCTCATGGTCCGAGTGACACGCCACAG
  CCTCTTTTGGATTTTGATACAGATGATCTTGATCTCAACAGTCTCAGGATCCAGCCAGTC
  CGCTCTGACCCCGTCAGCATGCCAGGGTCATCCCGTCCAGTCTCTGATCGAAGGGGAGTT
  TCCACAGTGATTGATGCTGCCTCAGGTACCTTTGACAGGAGCGTGACCCTGCTGGAGGTG
  TGCGGGAGCTGGCCTGAGGGCTTCGGGCTGCGGCACATGTCCTCCATGGAGCACACGGAG
  GAGGGCCTCCGGGAGCGACTTGCCGACGCCATGGCCGAGTCACCTAGCCGGGACGTCGTG
  GGATCCGGAACAGAACTTCAGCGAGAGGGAAGCATCGAGACTCTGAGTAACAGCTCAGGC
  TCCACCAGCGGCAGCATACCAAGAAACTTTGATGGCTACCGATCTCCGCTGCCCACCAAT
  GAGAGCCAGCCCCTCAGCCTCTTCCCGACTGGCTTCCCGTAG
  
  Clone variation with respect to NM_017679.3
  260 a=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_017679 unedited
  CCCGCAATTACCCCGCCCGTTGCCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTAT
  ATAAGCAGAGCTCAGTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCG
  GCCGCGAATTCGGCACGAGGAACCGGCGGGGCGGCCGGTTTTATGAATGAAGCTATGGCT
  ACAGATTCCCCAAGAAGACCCAGTCGTTGTACTGGTGGAGTTGTGGTTCGCCCCCAGGCT
  GTCACAGAGCAGTCCTACATGGAAAGTGTTGTGACTTTTCTGCAGGATGTTGTGCCACAG
  GCTTACAGTGGAACACCTCTAACAGAAGAAAAGGAGAAAATAGTCTGGGTCAGATTTGAA
  AATGCAGATTTAAATGATACATCAAGAAATCTGGAATTTCATGAAATACATAGTACTGGG
  AGTGAACCGCCTTTGTTGATTATGATTGGCTACAGTGATGGAATGCAGGTCTGGAGCATC
  CCTATCAGTGGCGAAGCACAAGAGCTCTTCTCTGTTCGACATGGCCCAATTCGAGCGGCT
  AGAATCTTGCCTGCTCCACAGTTTGGTGCTCAAAAATGTGATAACTTTGCTGAAAAAAGA
  CCCCTCCTTGGTGTTTGTAAGAGCATTGGATCTTCTGGCACAAGCCCACCGTACTGTTGT
  GTGGATCTGTATTCACTTCGTACTGGGGAGATGGTCAAGTCCATTCAATTTAAGACACCT
  ATTTATGATCTCCATTGCAATAAACGGATCCTTGTCGTAGTCTTGCAGGAGAAAATTGCT
  GCCTTTGATAGCTGTACTTTCACGAGNACATCTTTGTTACCAGCTGCTATCCATGTCCAG
  NGCCAAACATGAATNCTAGTGCTCTTGGCAGCCGCTGGCTTGCTTATGCAGAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_017679 unedited
  ACCTTTGGGTGNCTGTCGTCCCATTTATTTGGGGCATGNACGTTGCACTTCTTCAACAGG
  GGCCTCAGTAACCACTGTTTCCTTCACTGATCAGTACAGGACCAGGGTAAAGGGGCTTAA
  AGATAAGAAAGACAAACTCTTCCCAGGAACAGATGGGGAAAGAAAGGAGGAAGAAGAGGC
  ATGTCCTCCCTTCCTCCTTCCCTAGTACTCTGGGCCTCCGTTCACCCCGTGCTGGAGTGG
  GGCTGACCAAGGGAAGCTGGGGGCAGTGTGTGTCACAGCCAGACATGAGCTGAGGCTGTG
  ACTGTCCACTCAGGGTCAAAATGGCCAGGTGGACGATCAACTCTGTCCCCACTCAGGCCC
  CCAGATCTGGTCACTGTTCCAGGCTCCCCCCACCCGCCCCACCGTGGGTATGGTTAAAAA
  ATACAAAAGCGGATCCAATGCAGGATGTCATATGCAAACATACACAGGGACCGAGCTCTT
  ACAGTCTCTCCTGGCCACAGCCTCCACCGACAGGTGTGGCAGAGGGCAAGTGCGCTGAGG
  TGCTTGGAGAAGGGTCTCTTCTCCATCCAGGTAGGATGGGCGGCTGCTGTCACTAAGCTT
  GGGGAAGGTGGTTGATGAAGGAAGAGCAGAGACTGAAGGGTAGGACCAGAGCGGGGCTTC
  TCCCCTCCTCCAGCAGGGGAGGGGGCTGGCCAGTCAGAAGCATGTTGCTGGTTCCTACGG
  GAAGCCAGTCGGGAAGAGGCTGAGGGGCTGCTTCCATTGGTGGGAGCCGAGATCGGAGCC
  ATCAAATTTCTTGGATGCTGCCCTGGTGGGCCTGGACTGTACCCAGAGTCCGAGGCTTCC
  CCTCCTTAAGTTTTGTCCGGATCCCCGCCCCCCGGCAGGTACTCGGCCTGGCGTCGGAAG
  TCGTCCCGGAGGCCTCTCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_017679
• Insert Size: 4000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_017679.2, NP_060149.2
• RefSeq Size: 3514 bp
• RefSeq ORF: 2742 bp
• Locus ID: 54828
• UniProt ID: Q9H6U6
• Cytogenetics: 17q23.2
• Gene Summary: Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation (By similarity). Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) lacks alternate in-frame exons in the 3' coding region, compared to variant 3, resulting in a shorter protein (isoform 2), compared to isoform 3.