NLRX1 (NM_024618) Human Untagged Clone

CAT#: SC125516

NLRX1 (untagged)-Human NLR family member X1 (NLRX1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NLRX1
• Synonyms: CLR11.3; DLNB26; NOD5; NOD9; NOD26
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC125516 sequence for NM_024618 edited (data generated by NextGen Sequencing)
  ATGAGGTGGGGCCACCATTTGCCCAGGGCCTCTTGGGGCTCTGGTTTTAGAAGAGCACTC
  CAGCGACCAGATGATCGTATCCCCTTCCTGATCCACTGGAGTTGGCCCCTTCAAGGGGAG
  CGTCCCTTTGGGCCCCCTAGGGCCTTTATACGCCACCACGGAAGCTCGGTAGATAGCGCT
  CCCCCACCCGGGAGGCATGGACGGCTGTTCCCCAGCGCCTCTGCAACTGAAGCTATACAG
  CGGCACCGCCGGAACCTGGCTGAGTGGTTCAGCCGGCTGCCCAGGGAGGAGCGCCAGTTT
  GGCCCAACCTTTGCCCTAGACACGGTCCACGTTGACCCTGTGATCCGCGAGAGTACCCCT
  GATGAGCTACTTCGCCCACCCGCGGAGCTGGCCCTGGAGCATCAGCCACCCCAGGCCGGG
  CTCCCCCCACTGGCCTTGTCTCAGCTCTTTAACCCGGATGCCTGTGGGCGCCGGGTGCAG
  ACAGTGGTGCTGTATGGGACAGTGGGCACAGGCAAGAGCACGCTGGTGCGCAAGATGGTT
  CTGGACTGGTGTTATGGGCGGCTGCCGGCCTTCGAGCTGCTCATCCCCTTCTCCTGTGAG
  GACCTGTCATCCCTGGGCCCTGCCCCAGCCTCCCTGTGCCAACTTGTGGCCCAGCGCTAC
  ACGCCCCTGAAGGAGGTTCTGCCCCTGATGGCTGCTGCTGGGTCCCACCTCCTCTTTGTG
  CTCCATGGCTTAGAGCATCTCAACCTCGACTTCCGGCTGGCAGGCACGGGACTTTGTAGT
  GACCCGGAGGAACCGCAGGAACCAGCTGCTATCATCGTCAACCTGCTGCGCAAATACATG
  CTGCCTCAGGCCAGCATTCTGGTGACCACTCGGCCCTCTGCCATTGGCCGTATCCCCAGC
  AAGTACGTGGGCCGCTATGGTGAGATCTGCGGTTTCTCTGATACCAACCTGCAGAAGCTC
  TACTTCCAGCTCCGCCTCAACCAGCCGTACTGCGGGTATGCCGTTGGCGGTTCAGGTGTC
  TCTGCCACACCAGCTCAGCGTGACCACCTGGTGCAGATGCTCTCCCGGAACCTGGAGGGG
  CACCACCAGATAGCCGCTGCCTGCTTCCTGCCGTCCTATTGCTGGCTCGTTTGTGCCACC
  TTGCACTTCCTGCATGCCCCCACGCCTGCTGGGCAGACCCTTACAAGCATCTATACCAGC
  TTCCTGCGCCTCAACTTCAGCGGGGAAACCCTGGACAGCACTGACCCCTCCAATTTGTCC
  CTGATGGCCTATGCAGCCCGAACCATGGGCAAGTTGGCCTATGAGGGGGTGTCCTCCCGC
  AAGACCTACTTCTCTGAATAGGATGTCTGTGGCTGCCTGGAGGCTGGCATCAGGACGGAG
  GAGGAGTTTCAGCTGCTGCACATCTTCCGTCGGGATGCCCTGAGGTTTTTCCTGGCCCCA
  TGTGTGGAGCCAGGGCGTGCAGGCACCTTCGTGTTCACCGTGCCCGCCATGCAGGAATAC
  CTGGCTGCCCTCTACATTGTGCTGGGTTTGCGCAAGACGACCCTGCAAAAGGTGGGCAAG
  GAAGTGGCTGAGCTCGTGGGCCGTGTTGGGGAGGACGTCAGCCTGGTACTGGGCATCATG
  GCCAAGCTGCTGCCTCTGCGGGCTCTGCCTCTGCTCTTCAACCTGATCAAGGTGGTTCCA
  CGAGTGTTTGGGCGCATGGTGGGTAAAAGCCGGGAGGCGGTGGCTCAGGCCATGGTGCTG
  GAGATGTTTCGAGAGGAGGACTACTACAACGATGATGTTCTGGACCAGATGGGCGCCAGT
  ATCCTGGGCGTGGAGGGCCCCCGGCGCCACCCAGATGAGCCCCCTGAGGATGAAGTCTTC
  GAGCTCTTCCCCATGTTCATGGGGGGGCTTCTCTCTGCCCACAACCGAGCTGTGCTAGCT
  CAGCTTGGCTGCCCCATCAAGAACCTGGATGCCCTGGAGAATGCCCAGGCCATCAAGAAG
  AAGCTGGGCAAGCTGGGCCGGCAGGTGCTGCCCCCATCAGAGCTCCTTGACCACCTCTTC
  TTCCACTATGAGTTCCAGAACCAGCGCTTCTCCGCTGAGGTGCTCAGCTCCCTGCGTCAG
  CTCAACCTGGCAGGTGTGCGCATGACACCAGTCAAGTGCACAGTGGTGGCAGCTGTGCTG
  GGCAGCGGAAGGCATGCCCTGGATGAGGTGAACTTGGCCTCCTGCCAGCTAGATCCTGCT
  GGGCTGCGCACACTCCTGCCTGTCTTCCTGCGTGCCCGGAAGCTGGGCTTGCAACTCAAC
  AGCCTGGGCCCTGAGGCCTGCAAGGACCTCCGAGACCTGTTGCTGCATGACCAGTGCCAA
  ATTACCACACTGCGGCTGTCCAACAACCCGCTGACGGCGGCAGGTGTTGCCGTGCTAATG
  GAGGGGCTGGCAGGAAACACCTCAGTGACGCACCTGTCCCTGCTGCACACGGGCCTTGGG
  GACGAAGGCCTGGAGCTGCTGGCTGCCCAGCTGGACCGCAACCGGCAGCTGCAGGAGCTG
  AACGTGGCGTACAACGGTGCTGGTGACACAGCGGCCCTGGCCCTGGCCAGAGCTGCCCGG
  GAGCACCCTTCCCTGGAACTGCTACACCTCTACTTCAATGAGCTGAGCTCAGAGGGCCGC
  CAGGTCTTGCGAGACTTGGGGGGTGCTGCTGAAGGTGGTGCCCGGGTGGTGGTGTCACTG
  ACAGAGGGGACGGCGGTGTCAGAATACTGGTCAGTGATCCTCAGTGAAGTCCAGCGGAAC
  CTCAATAGCTGGGATCGGGCCCGGGTTCAGCGACACCTTGAGCTCCTACTGCGGGATCTG
  GAAGATAGCCGGGGTGCCACCCTTAATCCTTGGCGCAAGGCCCAGCTGCTGCGAGTGGAG
  GGCGAGGTCAGGGCCCTCCTGGAGCAGCTGGGAAGCTCTGGAAGCTGA
  
  Clone variation with respect to NM_024618.2
  1339 g=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_024618 unedited
  ATAACACCCGCCCCGTTGNCGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAA
  GCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCG
  CGAATTCGGCACGAGGGGACGATGGCGGGACGGGTGGCGCCGGGGTTCCAGCCCTGCGCC
  TGCTCCGGAGCACCGGGCCCCTCTCGCTGACCCCCTCGTCCCAGGACCCCGCAGGCCCGA
  GTGCCTGGGCTCGTCCTCTTTCGCGCCCGCTGCCAGGACAGAAGTCGGTCCTAGGCCCCC
  CAGGCTCTGACCTTCTTTCCCAGGATGAGGTGGGGCCACCATTTGCCCAGGGCCTCTTGG
  GGCTCTGGTTTTAGAAGAGCACTCCAGCGACCAGATGATCGTATCCCCTTCCTGATCCAC
  TGGAGTTGGCCCCTTCAAGGGGAGCGTCCCTTTGGGCCCCCCTAGGCCTTTATACGCCAC
  CACGGAGCTCGGTAGATAGCGCTCCCCACCCCGGAGCATGGCTGGCTGTTCCCCACGCCT
  CTGCACTTGAGCTTTCAGGGGACCGGCGGACCTGCTGATTGGTTACCCGGCTGGCCAGGC
  GAAGGCCAGTTGGGCCCCCCTTTGCCCTAAACCGGCCCCGTTGACCTGTGGACCCCCCGA
  GTACCCTGGGGGAGCTCTTTGTCCCCCCCGGGCCTTGCCCTGGGCCATCAGCCCCCCCAG
  GCCGGGTTTCCCCCCGGCCCTGTTTCCCTTTTTACCCCCCCCCTTTGGGTCCCGCGGCCC
  CCGGGCGTCTTATTGTCCGCCGCCCTTCCTTACCACCCGCCCCCCAATGCCCTGTTCCCT
  TTCCCCCCGTTTTTTCCCCTTCCCTCCCTCCCTCTTTTCCCCCGGCCCTTCCTCTTCGTC
  CCCTCCCTCCCCCCCCAATAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_024618 unedited
  CCATGGACATTGGNATGGCAACTTCCAGGNCCAGNAAAGCACTGGGGNAGGGTCACAGGG
  ATGCCACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGT
  TTTTTTTTTTTTTTTTTGGAAGGCACACGGCTTTTTAATAGCAGCAAGTCAGGTGCATCT
  GCCTCGAGGGGCTACCAAGCCATCATACCATTGTGGCAAAGGGGGCATGAGGATGAGGAG
  AAAGCACCAATGTGAGGGCATCCTCGGTGTCCACAGGTGAGCATAAGGCAGGAGGGGAAG
  CTTCCAACACATCTGGATGGCGACACCCCTGGCATGGCAGACATAAGATGTGAGCCCCTT
  GGTGACACAGTCAGAGGCTCTTTGAGAGGAGGGGGAGGCAAGGTTGGTAGTGGTGCTTCA
  GGGCACTCTGGCCATCCAAATGCCACATGCTTTGGTCCTTCTAGCTGAATGGAGAGGAGG
  CATGTTCCATCTCCAAGCCCGAAGCATTGATTCACCATCTTTTAACTTGGAGATTCCAGA
  CTCAGTCCTGGTCAAACATGCCCTAGGAGGGCAACTGGCTCAGCTATGCCCATTCCTCTG
  CCTCCAGACCTGAAGGAATCTTTCTAGAGGGAGCAGTGCAAGCCAGGAGGCCACAGAGGG
  AAAAGGTTTAGGGCCAGTGGTCACATAGCTAGGTGCCTGCCGCCAGTGTCTCAGCTTACA
  GAGCTTCCCAGCTGCTCCAGGAGGGCCCTGACCTCGCCCCTCACTCGCAAGAAGTGGGGC
  CTTGCGCCAAGGATTAAAGGTGGCACCCCGGCTATCTTCCAAATCCCGCAATATGAGCTC
  CAAGTGTCGCTGAACCCGGGCCCGATCCCGCTATTGAGGTTCCCCTGCACTTACTTGAGA
  TCACG
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_024618
• Insert Size: 4000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_024618.2, NP_078894.2
• RefSeq Size: 3761 bp
• RefSeq ORF: 2928 bp
• Locus ID: 79671
• UniProt ID: Q86UT6
• Cytogenetics: 11q23.3
• Domains: LRR, LRR_RI
• Protein Pathways: RIG-I-like receptor signaling pathway
• Gene Summary: The protein encoded by this gene is a member of the NLR family and localizes to the outer mitochondrial membrane. The encoded protein is a regulator of mitochondrial antivirus responses. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2013]
  Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 4. All three variants encode the same protein.