CD137 (TNFRSF9) (NM_001561) Human Untagged Clone

SKU SC125363

TNFRSF9 (untagged)-Human tumor necrosis factor receptor superfamily, member 9 (TNFRSF9)

Product Data

• Type: Human Untagged Clone
• Target Symbol: CD137
• Synonyms: 4-1BB; CD137; CDw137; ILA
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001561 edited; GGAGTGGAAAGTTCTCCGGCAGCCCTGAGATCTCAAGAGTGACATTTGTGAGACCAGCTA; ATTTGATTAAAATTCTCTTGGAATCAGCTTTGCTAGTATCATACCTGTGCCAGATTTCAT; CATGGGAAACAGCTGTTACAACATAGTAGCCACTCTGTTGCTGGTCCTCAACTTTGAGAG; GACAAGATCATTGCAGGATCCTTGTAGTAACTGCCCAGCTGGTACATTCTGTGATAATAA; CAGGAATCAGATTTGCAGTCCCTGTCCTCCAAATAGTTTCTCCAGCGCAGGTGGACAAAG; GACCTGTGACATATGCAGGCAGTGTAAAGGTGTTTTCAGGACCAGGAAGGAGTGTTCCTC; CACCAGCAATGCAGAGTGTGACTGCACTCCAGGGTTTCACTGCCTGGGGGCAGGATGCAG; CATGTGTGAACAGGATTGTAAACAAGGTCAAGAACTGACAAAAAAAGGTTGTAAAGACTG; TTGCTTTGGGACATTTAACGATCAGAAACGTGGCATCTGTCGACCCTGGACAAACTGTTC; TTTGGATGGAAAGTCTGTGCTTGTGAATGGGACGAAGGAGAGGGACGTGGTCTGTGGACC; ATCTCCAGCCGACCTCTCTCCGGGAGCATCCTCTGTGACCCCGCCTGCCCCTGCGAGAGA; GCCAGGACACTCTCCGCAGATCATCTCCTTCTTTCTTGCGCTGACGTCGACTGCGTTGCT; CTTCCTGCTGTTCTTCCTCACGCTCCGTTTCTCTGTTGTTAAACGGGGCAGAAAGAAACT; CCTGTATATATTCAAACAACCATTTATGAGACCAGTACAAACTACTCAAGAGGAAGATGG; CTGTAGCTGCCGATTTCCAGAAGAAGAAGAAGGAGGATGTGAACTGTGAAATGGAAGTCA; ATAGGGCTGTTGGGACTTTCTTGAAAAGAAGCAAGGAAATATGAGTCATCCGCTATCACA; GCTTTCAAAAGCAAGAACACCATCCTACATAATACCCAGGATTCCCCCAACACACGTTCT; TTTCTAAATGCCAATGAGTTGGCCTTTAAAAATGCACCACTTTTTTTTTTTTTTTGACAG; GGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGCACCACCATGGCTCTCTGCAGCCTT; GACCTCTGGGAGCTCAAGTGATCCTCCTGCCTCAGTCTCCTGAGTAGCTGGAACTACAAG; GAAGGGCCACCACACCTGACTAACTTTTTTGTTTTTTGTTTGGTAAAGATGGCATTTCAC; CATGTTGTACAGGCTGGTCTCAAACTCCTAGGTTCACTTTGGCCTCCCAAAGTGCTGGGA; TTACAGACATGAACTGCCAGGCCCGGCCAAAATAATGCACCACTTTTAACAGAACAGACA; GATGAGGACAGAGCTGGTGATAAAAAAAAAAAAAAAAAAGCATTTTCTAGATACCACTTA; ACAGGTTTGAGCTAGTTTTTTTGAAATCCAAAGAAAATTATAGTTTAAATTCAATTACAT; AGTCCAGTGGTCCAACTATAATTATAATCAAAATCAATGCAGGTTTGTTTTTTGGTGCTA; ATATGACATATGACAATAAGCCACGAGGTGCAGTAAGTACCCGACTAAAGTTTCCGTGGG; TTCTGTCATGTAACACGACATGCTCCACCGTCAGGGGGGAGTATGAGCAGAGTGCCTGAG; TTTAGGGTCAAGGACAAAAAACCTCAGGCCTGGAGGAAGTTTTGGAAAGAGTTCAAGTGT; CTGTATATCCTATGGTCTTCTCCATCCTCACACCTTCTGCCTTTGTCCTGCTCCCTTTTA; AGCCAGGTTACATTCTAAAAATTCTTAACTTTTAACATAATATTTTATACCAAAGCCAAT; AAATGAACTGCATATGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA; AAAAAAAA;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001561 unedited; ATAGGGNNCGGCCGCGTAATTCGGCACGAGGGGTAGTTGGAAAGTTCTCCGGCAGCCCTG; AGATCTCAANAGTGACATTTGTGAGACCAGCTAATTTGATTAAAATTCTCTTGGAATCAG; CTTTGCTAGTATCATACCTGTGCCAGATTTCATCATGGGAAACAGCTGTTACAACATAGT; AGCCACTCTGTTGCTGGTCCTCAACTTTGAGAGGACAAGATCATTGCAGGATCCTTGTAG; TAACTGCCCAGCTGGTACATTCTGTGATAATAACAGGAATCAGATTTGCAGTCCCTGTCC; TCCAAATAGTTTCTCCAGCGCAGGTGGACAAAGGACCTGTGACATATGCAGGCAGTGTAA; AGGTGTTTTCAGGACCAGGAAGGAGTGTTCCTCCACCAGCAATGCAGAGTGTGACTGCAC; TCCAGGGTTTCACTGCCTGGGGGCAGGATGCAGCATGTGTGAACAGGATTGTAAACAAGG; TCAAGAACTGACAAAAAAAGGTTGTAAAGACTGTTGCTTTGGGACATTTAACGATCAGAA; ACGTGGCATCTGTCGACCCTGGACAAACTGTTCTTTGGATGGAAAGTCTGTGCTTGTGAA; TGGGACGAAGGAGAGGGACGTGGTCTGTGGACCATCTCCAGCCGACCTCTCTCCGGGAGC; ATCCTCTGTGACCCCGCCTGCCCCTGCGAGAGAGCCAGGACACTCTCCGCAGATCATCTC; CTTCTTTCTTGCGCTGACGTCGACTGCGTTGCTCTTCCTGCTGNTCTTCCTCACGCTCCG; TTTCTCTGTTGTTAAACGGGGCAAAAGAAACTCCTGTATATATTCCAACAACCATTTATG; AGACCAGTACAA;
• Restriction Sites: Please inquire
• ACCN: NM_001561
• Insert Size: 768 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001561.4, NP_001552.2
• RefSeq Size: 1935 bp
• RefSeq ORF: 768 bp
• Locus ID: 3604
• UniProt ID: Q07011
• Cytogenetics: 1p36.23
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction
• Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]