DPP8 (NM_017743) Human Untagged Clone

CAT#: SC125354

DPP8 (untagged)-Human dipeptidyl-peptidase 8 (DPP8), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DPP8
• Synonyms: DP8; DPRP-1; DPRP1; MST097; MSTP097; MSTP135; MSTP141
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_017743, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCAGCAGCAATGGAAACAGAACAGCTGGGTGTTGAGATATTTGAAACTGCGGACTGTGAGGAGAATA
  TTGAATCACAGGATCGGCCTAAATTGGAGCCTTTTTATGTTGAGCGGTATTCCTGGAGTCAGCTTAAAAA
  GCTGCTTGCCGATACCAGAAAATATCATGGCTACATGATGGCTAAGGCACCACATGATTTCATGTTTGTG
  AAGAGGAATGATCCAGATGGACCTCATTCAGACAGAATCTATTACCTTGCCATGTCTGGTGAGAACAGAG
  AAAATACACTGTTTTATTCTGAAATTCCCAAAACTATCAATAGAGCAGCAGTCTTAATGCTCTCTTGGAA
  GCCTCTTTTGGATCTTTTTCAGGCAACACTGGACTATGGAATGTATTCTCGAGAAGAAGAACTATTAAGA
  GAAAGAAAACGCATTGGAACAGTCGGAATTGCTTCTTACGATTATCACCAAGGAAGTGGAACATTTCTGT
  TTCAAGCCGGTAGTGGAATTTATCACGTAAAAGATGGAGGGCCACAAGGATTTACGCAACAACCTTTAAG
  GCCCAATCTAGTGGAAACTAGTTGTCCCAACATACGGATGGATCCAAAATTATGCCCTGCTGATCCAGAC
  TGGATTGCTTTTATACATAGCAACGATATTTGGATATCTAACATCGTAACCAGAGAAGAAAGGAGACTCA
  CTTATGTGCACAATGAGCTAGCCAACATGGAAGAAGATGCCAGATCAGCTGGAGTCGCTACCTTTGTTCT
  CCAAGAAGAATTTGATAGATATTCTGGCTATTGGTGGTGTCCAAAAGCTGAAACAACTCCCAGTGGTGGT
  AAAATTCTTAGAATTCTATATGAAGAAAATGATGAATCTGAGGTGGAAATTATTCATGTTACATCCCCTA
  TGTTGGAAACAAGGAGGGCAGATTCATTCCGTTATCCTAAAACAGGTACAGCAAATCCTAAAGTCACTTT
  TAAGATGTCAGAAATAATGATTGATGCTGAAGGAAGGATCATAGATGTCATAGATAAGGAACTAATTCAA
  CCTTTTGAGATTCTATTTGAAGGAGTTGAATATATTGCCAGAGCTGGATGGACTCCTGAGGGAAAATATG
  CTTGGTCCATCCTACTAGATCGCTCCCAGACTCGCCTACAGATAGTGTTGATCTCACCTGAATTATTTAT
  CCCAGTAGAAGATGATGTTATGGAAAGGCAGAGACTCATTGAGTCAGTGCCTGATTCTGTGACGCCACTA
  ATTATCTATGAAGAAACAACAGACATCTGGATAAATATCCATGACATCTTTCATGTTTTTCCCCAAAGTC
  ACGAAGAGGAAATTGAGTTTATTTTTGCCTCTGAATGCAAAACAGGTTTCCGTCATTTATACAAAATTAC
  ATCTATTTTAAAGGAAAGCAAATATAAACGATCCAGTGGTGGGCTGCCTGCTCCAAGTGATTTCAAGTGT
  CCTATCAAAGAGGAGATAGCAATTACCAGTGGTGAATGGGAAGTTCTTGGCCGGCATGGATCTAATATCC
  AAGTTGATGAAGTCAGAAGGCTGGTATATTTTGAAGGCACCAAAGACTCCCCTTTAGAGCATCACCTGTA
  CGTAGTCAGTTACGTAAATCCTGGAGAGGTGACAAGGCTGACTGACCGTGGCTACTCACATTCTTGCTGC
  ATCAGTCAGCACTGTGACTTCTTTATAAGTAAGTATAGTAACCAGAAGAATCCACACTGTGTGTCCCTTT
  ACAAGCTATCAAGTCCTGAAGATGACCCAACTTGCAAAACAAAGGAATTTTGGGCCACCATTTTGGATTC
  AGCAGGTCCTCTTCCTGACTATACTCCTCCAGAAATTTTCTCTTTTGAAAGTACTACTGGATTTACATTG
  TATGGGATGCTCTACAAGCCTCATGATCTACAGCCTGGAAAGAAATATCCTACTGTGCTGTTCATATATG
  GTGGTCCTCAGGTTGCTATTGCTGGGGCCCCAGTCACTCTGTGGATCTTCTATGATACAGGATACACGGA
  ACGTTATATGGGTCACCCTGACCAGAATGAACAGGGCTATTACTTAGGATCTGTGGCCATGCAAGCAGAA
  AAGTTCCCCTCTGAACCAAATCGTTTACTGCTCTTACATGGTTTCCTGGATGAGAATGTCCATTTTGCAC
  ATACCAGTATATTACTGAGTTTTTTAGTGAGGGCTGGAAAGCCATATGATTTACAGATCTATCCTCAGGA
  GAGACACAGCATAAGAGTTCCTGAATCGGGAGAACATTATGAACTGCATCTTTTGCACTACCTTCAAGAA
  AACCTTGGATCACGTATTGCTGCTCTAAAAGTGATATAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_017743 unedited
  TGTTGTAAACGACTCCTATTAGGCGGCCGCGACATTCGCACGAGGGCCAAGGCCGCTGCT
  ACTGCCGCCGCTGCTTCTTAGTGCCGCGTTCGCCGCCTGGGTTGTCACCGGCGCCGCCGC
  CGAGGAAGCCACTGCAACCAGGACCGGAGTGGAGGCGGCGCAGCATGAAGCGGCGCAGGC
  CCGCTCCATAGCGCACGTCGGGACGGTCCGGGCGGGGCCGGGGGGAAGGAAAATGCAACA
  TGGCAGCAGCAATGGAAACAGAACAGCTGGGTGTTGAGATATTTGAAACTGCGGACTGTG
  AGGAGAATATTGAATCACAGGATCGGCCTAAATTGGAGCCTTTTTATGTTGAGCGGTATT
  CCTGGAGTCAGCTTAAAAAGCTGCTTGCCGATACCAGAAAATATCATGGCTACATGATGG
  CTAAGGCACCACATGATTTCATGTTTGTGAAGAGGAATGATCCAGATGGACCTCATTCAG
  ACAGAATCTATTACCTTGCCATGTCTGGTGAGAACAGAGAAAATACACTGTTTTATTCTG
  AAATTCCCAAAACTATCAATAGAGCAGCAGTCTTAATGCTCTCTTGGAAGCCTCTTTTGG
  ATCTTTTTCAGCAACACTGGACTATGGGAATGTATTCTCGAGAAGAAGAACTATTAANAG
  AAAAAAAACGCTTTGGAACAGTCGGAATTGGTTCTTACGATTATCACCAAGGAAGGGGAC
  ATTTCTTGTTTAAGCCGGGGGTGGAATTTATACCTAAAAAAGGGAGGGCCCCAGGGATTT
  ACCCACAACCCTTTAGGCCCATCTTAGGGAAACTAATTGGCCCACCTACGGGGGGGGCCA
  AAATTTTGCCCTGGGGTACCAAAAAGGATGGGTTTTATACTAAAAACCAAATTGGGAAAA
  AACAAAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_017743 unedited
  CCATGTCATGGCATGGCACTCTCAGGNCCAGGAAAGCACTGGGGAAGGGTCACAGGGCAT
  GCCACCCGGGTATCTGTTCAGGAAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGT
  TTTTTTTTTTTTTTTTTTTTTAGAAATTCTTATGGTATTGCTGGGTCTCTCAGGAATATG
  TATCATTTGATTTTGAGCATGTGGGGTTAAGGTATTAGATTACTACCACAAACCGTAGAC
  CCCTGCATGGCACCACATTTATTTTCAGGAGTAGATGTTACATGGCAGGTATCAAAATGT
  GATGATCAATTCTGTGTTTTCTGTTGATTAAACCTCCTCATTTGGTTAAATAGCCAGTGT
  ATACCAGAGAGTTCTACACAGGTCAAAATTATATCACTTTTAGAGCAGCAATACGTGATC
  CAAGGTTTTCTTGAAGGTAGTGCAAAAGATGCAGTTCATAATGTTCTCCCGATTCAGGAA
  CTCTTATGCTGTGTCTCTCCTGAGGATAGATCTGTAAATCATATGGCTTTCCAGCCCTCA
  CTAAAAAACTCAGTAATATACTGGTATGTGCAAAATGGACATTCTCATCCAGGAAACCAT
  GTAAGAGCAGTAAACGATTTGGTTCAGAGGGGAACTTTTCTGCTTGCATGGCCACAGATC
  CTAAGTAATAGCCCTGTTCATTCTGGTCAGGGTGACCCATATAACGTTCCGTGTTTCCCG
  TAACCAAAAAGATCCCCAGGATGGCTGGGGCCCCCANCATTACCACCCCCGAAGATTTCT
  GACCTCTGCCTTTATGCCCTCAGGGAGAGGTTTTCCCCATAGGACCAGCCCGGGGTGCCC
  CACCNATCCACAGTTTTGACACCCNATCGGAGAGCTTTGTTTTGGGCCCCCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_017743
• Insert Size: 3000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_017743.3, NP_060213.2
• RefSeq Size: 3796 bp
• RefSeq ORF: 2349 bp
• Locus ID: 54878
• UniProt ID: Q6V1X1
• Cytogenetics: 15q22.31
• Domains: DPPIV_N_term
• Protein Families: Druggable Genome, Protease, Transmembrane
• Gene Summary: This gene encodes a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The encoded protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl peptidase IV, this protein may play a role in T-cell activation and immune function. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) lacks two exons in the 3' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.