FBXO21 (NM_033624) Human Untagged Clone

CAT#: SC124348

FBXO21 (untagged)-Human F-box protein 21 (FBXO21), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FBXO21
• Synonyms: FBX21
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_033624 edited
  GCGGCCCCAGGTACGCGGACAAGATGGCGGCGGCAGCAGTCGACAGCGCGATGGAGGTGG
  TGCCGGCGCTGGCGGAGGAGGCCGCGCCGGAGGTAGCGGGCCTCAGCTGCCTCGTCAACC
  TGCCGGGTGAGGTGCTGGAGTACATCCTGTGCTGCGGCTCGCTGACGGCCGCCGACATCG
  GCCGTGTCTCCAGCACCTGCCGGCGGCTGCGCGAGCTGTGCCAGAGCAGCGGGAAGGTGT
  GGAAGGAGCAGTTCCGGGTGAGGTGGCCTTCCCTTATGAAACACTACAGCCCCACCGACT
  ACGTCAATTGGTTGGAAGAGTATAAAGTTCGGCAAAAAGCTGGGTTAGAAGCGCGGAAGA
  TTGTAGCCTCGTTCTCAAAGAGGTTCTTTTCAGAGCACGTTCCTTGTAATGGCTTCAGTG
  ACATTGAGAACCTTGAAGGACCAGAGATTTTTTTTGAGGATGAACTGGTGTGTATCCTAA
  ATATGGAAGGAAGAAAAGCTTTGACCTGGAAATACTACGCAAAAAAAATTCTTTACTACC
  TGCGGCAACAGAAGATCTTAAATAATCTTAAGGCCTTTCTTCAGCAGCCAGATGACTATG
  AGTCGTATCTTGAAGGTGCTGTATATATTGACCAGTACTGCAATCCTCTCTCCGACATCA
  GCCTCAAAGACATCCAGGCCCAAATTGACAGCATCGTGGAGCTTGTTTGCAAAACCCTTC
  GGGGCATAAACAGTCGCCACCCCAGCTTGGCCTTCAAGGCAGGTGAATCATCCATGATAA
  TGGAAATAGAACTCCAGAGCCAGGTGCTGGATGCCATGAACTATGTCCTTTACGACCAAC
  TGAAGTTCAAGGGGAATCGAATGGATTACTATAATGCCCTCAACTTATATATGCATCAGG
  TTTTGATTCGCAGAACAGGAATCCCAATCAGCATGTCTCTGCTCTATTTGACAATTGCTC
  GGCAGTTGGGAGTCCCACTGGAGCCTGTCAACTTCCCAAGTCACTTCTTATTAAGGTGGT
  GCCAAGGCGCAGAAGGGGCGACCCTGGACATCTTTGACTACATCTACATAGATGCTTTTG
  GGAAAGGCAAGCAGCTGACAGTGAAAGAATGCGAGTACTTGATCGGCCAGCACGTGACTG
  CAGCACTGTATGGGGTGGTCAATGTCAAGAAGGTGTTACAGAGAATGGTGGGAAACCTGT
  TAAGCCTGGGGAAGCGGGAAGGCATCGACCAGTCATACCAGCTCCTGAGAGACTCGCTGG
  ATCTCTATCTGGCAATGTACCCGGACCAGGTGCAGCTTCTCCTCCTCCAAGCCAGGCTTT
  ACTTCCACCTGGGAATCTGGCCAGAGAAGTCTTTCTGTCTTGTTTTGAAGGTGCTTGACA
  TCCTCCAGCACATCCAAACCCTAGACCCGGGGCAGCACGGGGCGGTGGGCTACCTGGTGC
  AGCACACTCTAGAGCACATTGAGCGCAAAAAGGAGGAGGTGGGCGTAGAGGTGAAGCTGC
  GCTCCGATGAGAAGCACAGAGATGTCTGCTACTCCATCGGGCTCATTATGAAGCATAAGA
  GGTATGGCTATAACTGTGTGATCTACGGCTGGGACCCCACCTGCATGATGGGACACGAGT
  GGATCCGGAACATGAACGTCCACAGCCTGCCGCACGGCCACCACCAGCCTTTCTATAACG
  TGCTGGTGGAGGACGGCTCCTGTCGATACGCAGCCCAAGAAAACTTGGAATATAACGTGG
  AGCCTCAAGAAATCTCACACCCTGACGTGGGACGCTATTTCTCAGAGTTTACTGGCACTC
  ACTACATCCCAAACGCAGAGCTGGAGATCCGGTATCCAGAAGATCTGGAGTTTGTCTATG
  AAACGGTGCAGAATATTTACAGTGCAAAGAAAGAGAACATAGATGAGTAAAGTCTAGAGA
  GGACATTGCACCTTTGCTGCTGCTGCTATCTTCCAAGAGAACGGGACTCCGGAAGAAGAC
  GTCTCCACGGAGCCCTCGGGACCTGCTGCACCAGGAAAGCCACTCCACCAGTAGTGCTGG
  TTGCCTCCTACTAAGTTTAAATACCGTGTGCTCTTCCCCAGCTGCAAAGACAATGTTGCT
  CTCCGCCTACACTAGTGAATTAATCTGAAAGGCACTGTGTCAGTGGCATGGCTTGTATGC
  TTGTCCTGTGGTGACAGTTTGTGACATTCTGTCTTCATGAGGTCTCACAGTCGACGCTCC
  TGTAATCATTCTTTGTATTCACTCCATTCCCCTGTCTGTCTGCATTTGTCTCAGAACATT
  TCCTTGGCTGGACAGATGGGGTTATGCATTTGCAATAATTTCCTTCTGATTTCTCTGTGG
  AACGTGTTCGGTCCCGAGTGAGGACTGTGTGTCTTTTTACCCTGAAGTTAGTTGCATATT
  CAGAGGTAAAGTTGTGTGCTATCTTGGCAGCATCTTAGAGATGGAGACATTAACAAGCTA
  ATGGTAATTAGAATCATTTGAATTTATTTTTTTCTAATATGTGAAACACAGATTTCAAGT
  GTTTTATCTTTTTTTTTTAAATTTAAATGGGAATATAACACAGTTTTCCCTTCCATATTC
  CTCTCTTGAGTTTATGCACATCTCTATAAATCATTAGTTTTCTATTTTATTACATAAAAT
  TCTTTTAGAAAATGCAAATAGTGAACTTTGTGAATGGATTTTTCCATACTCATCTACAAT
  TCCTCCATTTTAAATGACTACTTTTATTTTTTAATTTAAAAAATCTACTTCAGTATCATG
  AGTAGGTCTTACATCAGTGATGGGTTCTTTTTGTAGTGAGACATACAAATCTGATGTTAA
  TGTTTGCTCTTAGAAGTCATACTCCATGGTCTTCAAAGACCAAAAAAATGAGGTTTTGCT
  TTTGTAATCAGGAAAAAAAAAAATTAATGAACCTTAAAAAAAAAAAAAAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_033624
• Insert Size: 2900 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_033624.2.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_033624.2, NP_296373.1
• RefSeq Size: 4248 bp
• RefSeq ORF: 1887 bp
• Locus ID: 23014
• UniProt ID: O94952
• Cytogenetics: 12q24.22
• Domains: F-box
• Gene Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) contains an additional 21 nt fragment within the coding region, and thus encodes a 7 aa longer isoform than variant 2.