MMP10 (NM_002425) Human Untagged Clone

CAT#: SC123825

MMP10 (untagged)-Human matrix metallopeptidase 10 (stromelysin 2) (MMP10)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MMP10
• Synonyms: SL-2; STMY2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002425 edited
  ACAAAGAAGGTAAGGGCAGTGAGAATGATGCATCTTGCATTCCTTGTGCTGTTGTGTCTG
  CCAGTCTGCTCTGCCTATCCTCTGAGTGGGGCAGCAAAAGAGGAGGACTCCAACAAGGAT
  CTTGCCCAGCAATACCTAGAAAAGTACTACAACCTCGAAAAGGATGTGAAACAGTTTAGA
  AGAAAGGACAGTAATCTCATTGTTAAAAAAATCCAAGGAATGCAGAAGTTCCTTGGGTTG
  GAGGTGACAGGGAAGCTAGACACTGACACTCTGGAGGTGATGCGCAAGCCCAGGTGTGGA
  GTTCCTGACGTTGGTCACTTCAGCTCCTTTCCTGGCATGCCGAAGTGGAGGAAAACCCAC
  CTTACATACAGGATTGTGAATTATACACCAGATTTGCCAAGAGATGCTGTTGATTCTGCC
  ATTGAGAAAGCTCTGAAAGTCTGGGAAGAGGTGACTCCACTCACATTCTCCAGGCTGTAT
  GAAGGAGAGGCTGATATAATGATCTCTTTTGCAGTTAAAGAACATGGAGACTTTTACTCT
  TTTGATGGCCCAGGACACAGTTTGGCTCATGCCTACCCACCTGGACCTGGGCTTTATGGA
  GATATTCACTTTGATGATGATGAAAAATGGACAGAAGATGCATCAGGCACCAATTTATTC
  CTCGTTGCTGCTCATGAACTTGGCCACTCCCTGGGGCTCTTTCACTCAGCCAACACTGAA
  GCTTTGATGTACCCACTCTACAACTCATTCACAGAGCTCGCCCAGTTCCGCCTTTCGCAA
  GATGATGTGAATGGCATTCAGTCTCTCTACGGACCTCCCCCTGCCTCTACTGAGGAACCC
  CTGGTGCCCACAAAATCTGTTCCTTCGGGATCTGAGATGCCAGCCAAGTGTGATCCTGCT
  TTGTCCTTCGATGCCATCAGCACTCTGAGGGGAGAATATCTGTTCTTTAAAGACAGATAT
  TTTTGGCGAAGATCCCACTGGAACCCTGAACCTGAATTTCATTTGATTTCTGCATTTTGG
  CCCTCTCTTCCATCATATTTGGATGCTGCATATGAAGTTAACAGCAGGGACACCGTTTTT
  ATTTTTAAAGGAAATGAGTTCTGGGCCATCAGAGGAAATGAGGTACAAGCAGGTTATCCA
  AGAGGCATCCATACCCTGGGTTTTCCTCCAACCATAAGGAAAATTGATGCAGCTGTTTCT
  GACAAGGAAAAGAAGAAAACATACTTCTTTGCAGCGGACAAATACTGGAGATTTGATGAA
  AATAGCCAGTCCATGGAGCAAGGCTTCCCTAGACTAATAGCTGATGACTTTCCAGGAGTT
  GAGCCTAAGGTTGATGCTGTATTACAGGCATTTGGATTTTTCTACTTCTTCAGTGGATCA
  TCACAGTTTGAGTTTGACCCCAATGCCAGGATGGTGACACACATATTAAAGAGTAACAGC
  TGGTTACATTGCTAGGCGAGATAGGGGGAAGACAGATATGGGTGTTTTTAATAAATCTAA
  TAATTATTCATCTAATGTATTATGAGCCAAAATGGTTAATTTTTCCTGCATGTTCTGTGA
  CTGAAGAAGATGAGCCTTGCAGATATCTGCATGTGTCATGAAGAATGTTTCTGGAATTCT
  TCACTTGCTTTTGAATTGCACTGAACAGAATTAAGAAATACTCATGTGCAATAGGTGAGA
  GAATGTATTTTCATAGATGTGTTATTACTTCCTCAATAAAAAGTTTTATTTTGGGCCTGT
  TCCTTAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002425 unedited
  NNNCCCCTGTTCGGATTTGTATACGACTCACTTAGGCGGCCGCGCAATTCGCACGAGGAC
  AAAGAAGTAAGGGCAGTGAGAATGATGCATCTTGCATTCCTTGTGCTGTTGTGTCTGCCA
  GTCTGCTCTGCCTATCCTCTGAGTGGGGCAGCAAAAGAGGAGGACTCCAACAAGGATCTT
  GCCCAGCAATACCTAGAAAAGTACTACAACCTCGAAAAGGATGTGAAACAGTTTAGAAGA
  AAGGACAGTAATCTCATTGTTAAAAAAATCCAAGGAATGCAGAAGTTCCTTGGGTTGGAG
  GTGACAGGGAAGCTAGACACTGACACTCTGGAGGTGATGCGCAAGCCCAGGTGTGGAGTT
  CCTGACGTTGGTCACTTCAGCTCCTTTCCTGGCATGCCGAAGTGGAGGAAAACCCACCTT
  ACATACAGGATTGTGAATTATACACCAGATTTGCCAAGAGATGCTGTTGATTCTGCCATT
  GAGAAAGCTCTGAAAGTCTGGGAAGAGGTGACTCCACTCACATTCTCCAGGCTGTATGAA
  GGAGAGGCTGATATAATGATCTCTTTTGCAGTTAAAGAACATGGAGACTTTTACTCTTTT
  GATGGCCCAGGACACAGTTTGGCTCATGCCTACCCACCTGGACCTGGGCTTTATGGAGAT
  ATTCACTTTGATGATGATGAAAAATGGACAGAAGATGCATCAGGCACCAATTTATTCCTC
  GTTGCTGCTCATGAACTTGGCCACTCCCTGGGGCTCTTTCACTCAGCCAACACTGAAGCT
  NTGATGTACCCACTCTACAACTCATTCACAGAGCTCGCCCAGTTCCGCCTTTCGCAAGAG
  ATGTGAATGGCATTCAGTCTCTCTACGGACCCTCCCCTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_002425
• Insert Size: 1850 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002425.1, NP_002416.1
• RefSeq Size: 1743 bp
• RefSeq ORF: 1431 bp
• Locus ID: 4319
• UniProt ID: P09238
• Cytogenetics: 11q22.2
• Protein Families: Druggable Genome, Protease
• Gene Summary: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. The gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]