GABRA2 (BC022488) Human Untagged Clone

CAT#: SC123560

GABRA2 (untagged)-Human gamma-aminobutyric acid (GABA) A receptor, alpha 2 (cDNA clone MGC:26342 IMAGE:4812001), complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GABRA2
• Synonyms: FLJ97076; gamma-aminobutyric acid (GABA) A receptor, alpha 2; gamma-aminobutyric acid A receptor, alpha 2; OTTHUMP00000125269
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC022488 edited
  AAGCGGCCTCGGGGAGCAGCCCGAGGCTGCGCGTGGGCTCCGCTCCTCCGGCGAGGTGTG
  GGCGAGGGGAGCGGCGCTCCGAGCGCACCCAGGCGCCCGACGCCGCCCGGGTCTGCGCCG
  CTGCTAGTGCCAGGCGGGCGACGAGCGGCGGTGATGAAGACAAAATTGAACATCTACAAC
  ATGCAGTTCCTGCTTTTTGTTTTCTTGGTGTGGGACCCTGCCAGGTTGGTGCTGGCTAAC
  ATCCAAGAAGATGAGGCTAAAAATAACATTACCATCTTTACGAGAATTCTTGACAGACTT
  CTGGATGGTTACGATAATCGGCTTAGACCAGGACTGGGAGACAGTATTACTGAAGTCTTC
  ACTAACATCTACGTGACCAGTTTTGGCCCTGTCTCAGATACAGATATGGAATATACAATT
  GATGTTTTCTTTCGACAAAAATGGAAAGATGAACGTTTAAAATTTAAAGGTCCTATGAAT
  ATCCTTCGACTAAACAATTTAATGGCTAGCAAAATCTGGACTCCAGATACCTTTTTTCAC
  AATGGGAAAAAATCAGCAGCTCATAATATGACAATGCCAAATAAGTTGCTTCGAATTCAG
  GATGATGGGACTCTGCTGTATACCATGAGGCTTACAGTTCAAGCTGAATGCCCAATGCAC
  TTGGAGGATTTCCCAATGGATGCTCATTCATGTCCTCTGAAATTTGGCAGCTATGCATAT
  ACAACTTCAGAGGTCACTTATATTTGGACTTACAATGCATCTGATTCAGTACAGGTTGCT
  CCTGATGGCTCTAGGTTAAATCAATATGACCTGCTGGGCCAATCAATCGGAAAGGAGACA
  ATTAAATCCAGTACAGGTGAATATACTGTAATGACAGCTCATTTCCACCTGAAAAGAAAA
  ATTGGGTATTTTGTGATTCAAACCTATCTGCCTTGCATCATGACTGTCATTCTCTCCCAA
  GTTTCATTCTGGCTTAACAGAGAATCTGTGCCTGCAAGAACTGTGTTTGGAGTAACAACT
  GTCCTAACAATGACAACTCTAAGCATCAGTGCTCGGAATTCTCTCCCCAAAGTGGCTTAT
  GCAACTGCCATGGACTGGTTTATTGCTGTTTGTTATGCATTTGTGTTCTCTGCCCTAATT
  GAATTTGCAACTGTTAATTACTTCACCAAAAGAGGATGGGCTTGGGATGGGAAGAGTGTA
  GTAAATGACAAGGTAAGTGAGAGCTTCCGTGTTATCATTATTAAGAAAATACCCTAATGA
  ATTCCGCTTGTAACAGATATGTTTCTAAAATCCTGACATTAAAGACATCCATATATATAT
  GAATTTGAATCATATCAATTTCTTTTAAAGTGTTCTTGCCTGAAATCCTTTAGGAGTTCT
  TGTAGTACTAATACTTCCATTAAAACCACTCCGTAGCATCTGTTGAGCTGTATGTGTCAG
  GCACTGTGCTAAGTGTTTTACATATGCTCTCTCACATAATCTTTATAGCATCCTTATGAC
  TAGACTGCCTTCTTATTCTTATTTTTACTCATGAAGAATCTGAAGCAGTAAAGTTATTTT
  CTTGCCCAAGCTTACACAACTTGTTAGTAAGTATACTTGAACTCCGATCTACCTGTCTGA
  CTGTTAAGTTCATGGTTTTAACACCACACTGCATTATTATAAAGAGATTAGAAAAAGAAA
  ATGGGCATTAATTTTACTTATTATAGAATTCCAGGCTCTATCAATGAATTGAATCCTCTT
  CACCTGTTCCAGTCTCTGCTGATTTATTGTAAAAGCCCGGATAGCATTTTTTTAAAATCT
  TTCCCATGTTGCATGGAATAAATATGTCGGTGCTGGAATGCTTAGGAATTTTAAATTGTT
  CATATGGTCTAAAAGGGAAAAGTTATTTGTTTTTAAGATTAACTTCTTTTGAGATTATTG
  CTGTCCATATTTAGGTTTCAAGTACTGAATCTAATGGGAGATTTGTGCATTGATATAACA
  GCTGTTTCCTTTCATACTCTGTAGATTATGTATCTGCCTAAAGGGAGGCTTTGAATGTAT
  CATAATCATCTATATTCTTAATAATGGTAAAAAGTTGTATTCAGAGGATATCTTTAACAT
  TGTATCAACCTAAATGCTTCTTTTATTAAATTTGGATTAACATACTTGCAGATTTGATTT
  CTTTTTCAGTTATTTGAATATATTTTTTCATTTCTATGACCATGTTACAGTTTAAATATA
  CAAGCAGTAAATGTTATAGTTTAAAAGTCTTGGTCTTTTTCCTTAATTTTGTAAGCCATA
  GAAATTTTAATAAGACTGATTATTTATTTCATTTTATAAGTTGTGTTTTCCCTACTAACG
  GAGCCAACAAATAAATATTAAAAGGAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC022488 unedited
  GCCATCCGGTTTGATAAACACTCATGATGGGTGCGGCAAAAAACCTCGNCCCTTCCCGGN
  ACCATGACTTTTGAGCCTCCACACCAAAGCGGAAGGGCGGGCCCTACTGCATAAGATCCA
  AGGGAACGAGCTGGAGCCCCTGAACCGTCCGCAGCTCAAGATCCCCCTGGAGCGGCCCCT
  GGGCGAGGTGTACCTGGACAGCAGCAAGCCCGCCGTGTACTTTTTTTTCGAGGGCGCCGC
  CTACGAGTTGGGGGCGGCGGCCGCATAATTTCGTATAGCATACATTATACGAAGTTATGG
  ATCAGGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGAAGCGGCCTCGGGGAGCAGC
  CCGAGGCTGCGCGTGGGCTCCGCTCCTCCGGCGAGGTGTGGGCGAGGGGAGCGGCGCTCC
  GAGCGCACCCAGGCGCCCGACGCCGCCCGGGTCTGCGCCGCTGCTAGTGCCAGGCGGGCG
  ACGAGCGGCGGTGATGAAGACAAAATTGAACATCTACAACATGCAGTTCCTGCTTTTTGT
  TTTCTTGGTGTGGGACCCTGCCAGGTTGGTGCTGGCTAACATCCAAGAAGATGAGGCTAA
  AAATAACATTACCCATCTGTACGAAAATTCTTGAACAGACTTTTGGGTGGTTACGATAAT
  TCGGTTAGAACAGGACTGGGGAGAAAGTATAACTGGAGTTCTTTCCTAAACACTACGTGG
  ACCCGGTTTTGGCCCTGGTTTTCAGAAACCGAATTTGGGAAATTACAAATTGATGGGTTT
  TCTTTCGCCACAAAAGGGGGAGAAAGAGCCGTTTAAAAATTAAAGGCGCCCTAGAAAATC
  CCTCTCGACAAAAACAATTTATGGGGTGGAGAAAATTTGGGGCGCCCGATAACCTTTTTT
  TCAAAAGGGGAGAAAAATCCCGGCCT
  
• Restriction Sites: Please inquire
• ACCN: BC022488
• Insert Size: 2381 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC022488.1, AAH22488.1
• RefSeq Size: 2381 bp
• RefSeq ORF: 1101 bp
• Locus ID: 2555
• Cytogenetics: 4p12
• Protein Families: Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction
• Gene Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]