Folate Binding Protein (FOLR1) (NM_016725) Human Untagged Clone

CAT#: SC122853

FOLR1 (untagged)-Human folate receptor 1 (adult) (FOLR1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Folate Binding Protein
• Synonyms: FBP; FOLR; FRalpha; NCFTD
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_016730 edited
  CCAATCCCAGGCTCCACTCCTGGGCTCCATTCCCACTCCCTGCCTGTCTCCTAGGCCACT
  AAACCACAGCTGTCCCCTGGAATAAGGCAAGGGGGAGTGTAGAGCAGAGCAGAAGCCTGA
  GCCAGACGGAGAGCCACCTCCTCTCCCAGGGACAGACATGGCTCAGCGGATGACAACACA
  GCTGCTGCTCCTTCTAGTGTGGGTGGCTGTAGTAGGGGAGGCTCAGACAAGGATTGCATG
  GGCCAGGACTGAGCTTCTCAATGTCTGCATGAACGCCAAGCACCACAAGGAAAAGCCAGG
  CCCCGAGGACAAGTTGCATGAGCAGTGTCGACCCTGGAGGAAGAATGCCTGCTGTTCTAC
  CAACACCAGCCAGGAAGCCCATAAGGATGTTTCCTACCTATATAGATTCAACTGGAACCA
  CTGTGGAGAGATGGCACCTGCCTGCAAACGGCATTTCATCCAGGACACCTGCCTCTACGA
  GTGCTCCCCCAACTTGGGGCCCTGGATCCAGCAGGTGGATCAGAGCTGGCGCAAAGAGCG
  GGTACTGAACGTGCCCCTGTGCAAAGAGGACTGTGAGCAATGGTGGGAAGATTGTCGCAC
  CTCCTACACCTGCAAGAGCAACTGGCACAAGGGCTGGAACTGGACTTCAGGGTTTAACAA
  GTGCGCAGTGGGAGCTGCCTGCCAACCTTTCCATTTCTACTTCCCCACACCCACTGTTCT
  GTGCAATGAAATCTGGACTCACTCCTACAAGGTCAGCAACTACAGCCGAGGGAGTGGCCG
  CTGCATCCAGATGTGGTTCGACCCAGCCCAGGGCAACCCCAATGAGGAGGTGGCGAGGTT
  CTATGCTGCAGCCATGAGTGGGGCTGGGCCCTGGGCAGCCTGGCCTTTCCTGCTTAGCCT
  GGCCCTAATGCTGCTGTGGCTGCTCAGCTGACCTCCTTTTACCTTCTGATACCTGGAAAT
  CCCTGCCCTGTTCAGCCCCACAGCTCCCAACTATTTGGTTCCTGCTCCATGGTCGGGCCT
  CTGACAGCCACTTTGAATAAACCAGACACCGCAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016725 unedited
  NNAATGTCAAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCCAATC
  CCAGGCTCCACTCCTGGGCTCCATTCCCACTCCCTGCCTGTCTCCTAGGCCACTAAACCA
  CAGCTGTCCCCTGGAATAAGGCAAGGGGGAGTGTATAGCATAGCAGATGCCTGAGCCAGA
  CGGAGAGCCACCTCCTCTCCCATGGACAGACATGGCTCAGCGGATGACAACACAGCTGCT
  GCTCCTTCTAGTGTGGGTGGCTGTAGTAGGGGAGGCTCACACAAGGATTGCATGGGCCAG
  GACTGAGCTTCTCAATGTCTGCATGAACGCCAAGCACCACAAGGAAAAGCCAGGCCCCGA
  GGACAAGTTGCATGAGCAGTGTCGACCCTGGAGGAAGAATGCCTGCTGTTCTACCAACAC
  CAGCCAGGAAGCCCATAAGGATGTTTCCTACCTATATAGATTCAACTGGAACCACTGTGG
  AGAGATGGCACCTGCCTGCAAACGGCATTTCATCCAGGACACCTGCCTCTACGAGTGCTC
  CCCCAACTTGAGGCCCTGGATCCAGCAGGTGGATCAGAGCTGGCGCATAGAGCGGGTACT
  GAACGTGCCCCTGTGCAAAGAGGACTGTGAGCAATGGTGGGAAGATTGTCGCACCTCCTA
  CACCTGCAAGAGCAACTGGCACAAGGGCTGGAACTGGACTTCAGGGTCTAACAAGTGCGC
  AGTGNGAGCTGCCTGCCAACCTGTTCATTTCTACTTCCNCACACCCACGGTTCTGTGCAT
  TGAAATCTGGACTCACTCCTACAAGGTCAGCAACTACAGCCCGAGGAGTGGCCGCTGCAT
  CCAGATGTGGTTCGACCCAGCCCAGGGCAACCCCATGAGGGAGTGCCGAGGT
  
• Restriction Sites: Please inquire
• ACCN: NM_016725
• Insert Size: 1000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_016725.1, NP_057937.1
• RefSeq Size: 1104 bp
• RefSeq ORF: 774 bp
• Locus ID: 2348
• UniProt ID: P15328
• Cytogenetics: 11q13.4
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Gene Summary: The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]
  Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 7. Variants 1, 2, 4 and 7 all encode the same protein.