MMP7 (NM_002423) Human Untagged Clone

CAT#: SC122627

MMP7 (untagged)-Human matrix metallopeptidase 7 (matrilysin, uterine) (MMP7)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MMP7
• Synonyms: MMP-7; MPSL1; PUMP-1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002423 edited
  GTCCAAGAACAATTGTCTCTGGACGGCAGCTATGCGACTCACCGTGCTGTGTGCTGTGTG
  CCTGCTGCCTGGCAGCCTGGCCCTGCCGCTGCCTCAGGAGGCGGGAGGCATGAGTGAGCT
  ACAGTGGGAACAGGCTCAGGACTATCTCAAGAGATTTTATCTCTATGACTCAGAAACAAA
  AAATGCCAACAGTTTAGAAGCCAAACTCAAGGAGATGCAAAAATTCTTTGGCCTACCTAT
  AACTGGAATGTTAAACTCCCACGTCATAGAAATAATGCAGAAGCCCAGATGTGGAGTGCC
  AGATGTTGCAGAATACTCACTATTTCCAAATAGCCCAAAATGGACTTCCAAAGTGGTCAC
  CTACAGGATCGTATCATATACTCGAGACTTACCGCATATTACAGTGGATCGATTAGTGTC
  AAAGGCTTTAAACATGTGGGGCAAAGAGATCCCCCTGCATTTCAGGAAAGTTGTATGGGG
  AACTGCTGACATCATGATTGGCTTTGCGCGAGGAGCTCATGGGGACTCCTACCCATTTGA
  TGGGCCAGGAAACACGCTGGCTCATGCCTTTGCGCCTGGGACAGGTCTCGGAGGAGATGC
  TCACTTCGATGAGGATGAACGCTGGACGGATGGTAGCAGTCTAGGGATTAACTTCCTGTA
  TGCTGCAACTCATGAACTTGGCCATTCTTTGGGTATGGGACATTCCTCTGATCCTAATGC
  AGTGATGTATCCAACCTATGGAAATGGAGATCCCCAAAATTTTAAACTTTCCCAGGATGA
  TATTAAAGGCATTCAGAAACTATATGGAAAGAGAAGTAATTCAAGAAAGAAATAGAAACT
  TCAGGCAGAACATCCATTCATTCATTCATTGGATTGTATATCATTGTTGCACAATCAGAA
  TTGATAAGCACTGTTCTTCCACTCCATTTAGCAATTATGTCACCCTTTTTTATTGCAGTT
  GGTTTTTGAATGTCTTTCACTCCTTTTAAGGATAAACTCCTTTATGGTGTGACTGTGTCT
  TATTCATCTATACTTGCAGTGGGTAGATGTCAATAAATGTTACATACACAAATAAATAAA
  ATGTTTATTCCATGGTAAATTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002423 unedited
  NNTTCTGTCAGAATTGTATACGACTCACTATAGGCGGCCGCGATTCGGCACGAGGGTCCA
  AGAACAATTGTCTCTGGACGGCAGCTATGCGACTCACCGTGCTGTGTGCTGTGTGCCTGC
  TGCCTGGCAGCCTGGCCCTGCCGCTGCCTCAGGAGGCGGGAGGCATGAGTGAGCTACAGT
  GGGAACAGGCTCAGGACTATCTCAAGAGATTTTATCTCTATGACTCAGAAACAAAAAATG
  CCAACAGTTTAGAAGCCAAACTCAAGGAGATGCAAAAATTCTTTGGCCTACCTATAACTG
  GAATGTTAAACTCCCACGTCATAGAAATAATGCAGAAGCCCAGATGTGGAGTGCCAGATG
  TTGCAGAATACTCACTATTTCCAAATAGCCCAAAATGGACTTCCAAAGTGGTCACCTACA
  GGATCGTATCATATACTCGAGACTTACCGCATATTACAGTGGATCGATTAGTGTCAAAGG
  CTTTAAACATGTGGGGCAAAGAGATCCCCCTGCATTTCANGAAAGTTGTATGGGGAACTG
  CTGACATCATGATTGGCTTTGCGCGAGGAGCTCATGGGGACTCCTACCCATTTGATGGGC
  CAGGAAACACGCTGGCTCATGCCTTTGCGCCTGGGACAGGTCTCGGAGGAGATGCTCACT
  TCGATGAGGATGAACGCTGGACGGATGGTAGCAGTCTAGGGATTAACTTCCTGTATGCTG
  CAACTCATGAACTTGGCCATTCTTTGGGTATGGGACATTCCTCTGATCCTAATGCAGTGA
  TGTATCCAACCTATGGAAATGGAGATCCCCANAATTTTAAAACTTTCCAGGATGATATTA
  AAGGCATTCAGAAACTATATGGGAAAGAGAAGTATTCAAGAAAGAATAGNAA
  
• Restriction Sites: Please inquire
• ACCN: NM_002423
• Insert Size: 1140 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002423.2, NP_002414.1
• RefSeq Size: 1127 bp
• RefSeq ORF: 804 bp
• Locus ID: 4316
• UniProt ID: P09237
• Cytogenetics: 11q22.2
• Protein Families: Druggable Genome, Protease
• Protein Pathways: Wnt signaling pathway
• Gene Summary: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers. [provided by RefSeq, Jan 2016]