Amphiregulin (AREG) (NM_001657) Human Untagged Clone

CAT#: SC122605

AREG (untagged)-Human amphiregulin (AREG)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Amphiregulin
• Synonyms: AR; AREGB; CRDGF; SDGF
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001657 edited
  GGGGAGACGTTCGCACACCTGGGTGCCAGCGCCCCAGAGGTCCCGGGACAGCCCGAGGCG
  CCGCGCCCGCCGCCCCGAGCTCCCCAAGCCTTCGAGAGCGGCGCACACTCCCGGTCTCCA
  CTCGCTCTTCCAACACCCGCTCGTTTTGGCGGCAGCTCGTGTCCCAGAGACCGAGTTGCC
  CCAGAGACCGAGACGCCGCCGCTGCGAAGGACCAATGAGAGCCCCGCTGCTACCGCCGGC
  GCCGGTGGTGCTGTCGCTCTTGATACTCGGCTCAGGCCATTATGCTGCTGGATTGGACCT
  CAATGACACCTACTCTGGGAAGCGTGAACCATTTTCTGGGGACCACAGTGCTGATGGATT
  TGAGGTTACCTCAAGAAGTGAGATGTCTTCAGGGAGTGAGATTTCCCCTGTGAGTGAAAT
  GCCTTCTAGTAGTGAACCGTCCTCGGGAGCCGACTATGACTACTCAGAAGAGTATGATAA
  CGAACCACAAATACCTGGCTATATTGTCGATGATTCAGTCAGAGTTGAACAGGTAGTTAA
  GCCCCCCCAAAACAAGACGGAAAGTGAAAATACTTCAGATAAACCCAAAAGAAAGAAAAA
  GGGAGGCAAAAATGGAAAAAATAGAAGAAACAGAAAGAAGAAAAATCCATGTAATGCAGA
  ATTTCAAAATTTCTGCATTCACGGAGAATGCAAATATATAGAGCACCTGGAAGCAGTAAC
  ATGCAAATGTCAGCAAGAATATTTCGGTGAACGGTGTGGGGAAAAGTCCATGAAAACTCA
  CAGCATGATTGACAGTAGTTTATCAAAAATTGCATTAGCAGCCATAGCTGCCTTTATGTC
  TGCTGTGATCCTCACAGCTGTTGCTGTTATTACAGTCCAGCTTAGAAGACAATACGTCAG
  GAAATATGAAGGAGAAGCTGAGGAACGAAAGAAACTTCGACAAGAGAATGGAAATGTACA
  TGCTATAGCATAACTGAAGATAAAATTACAGGATATCACATTGGAGTCACTGCCAAGTCA
  TAGCCATAAATGATGAGTCGGTCCTCTTTCCAGTGGATCATAAGACAATGGACCCTTTTT
  GTTATGATGGTTTTAAACTTTCAATTGTCACTTTTTATGCTATTTCTGTATATAAAGGTG
  CACGAAGGTAAAAAGTATTTTTTCAAGTTGTAAATAATTTATTTAATATTTAATGGAAGT
  GTATTTATTTTACAGCTCATTAAACTTTTTTAACCAAACAGATCAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001657 unedited
  CCGCAAGTTCGGGATTTGNTATACGACTTCACTATAGGGCGGCGCGCGATTCGGCCATTA
  CGGCCGGGGAGACGTTCGCACACCTGGGTGCCAGCGCCCCAGAGTCCCGGGACAGCCCGA
  GGCGCCGCGCCCGCCGCCCCGAGCTCCCCAAGCCTTCGAGAGCGGCGCACACTCCCGGTC
  TCCACTCGCTCTTCCAACACCCGCTCGTTTTGGCGGCAGCTCGTGTCCCAGAGACCGAGT
  TGCCCCAGAGACCGAGACGCCGCCGCTGCGAAGGACCAATGAGAGCCCCGCTGCTACCGC
  CGGCGCCGGTGGTGCTGTCGCTCTTGATACTCGGCTCAGGCCATTATGCTGCTGGATTGG
  ACCTCAATGACACCTACTCTGGGAAGCGTGAACCATTTTCTGGGGACCACAGTGCTGATG
  GATTTGAGGTTACCTCAAGAAGTGAGATGTCTTCAGGGAGTGAGATTTCCCCTGTGAATG
  AAATGCCTTCTAGTAGTGAACCGTCCTCGGGAGCCGACTATGACTACTCAGAAAAGTATG
  ATAACGAACCACAAATACCTGGCTATATTGGACATGATTCAGTCATAATTGAACAGGTTG
  TTAAGCCCCCCCAAAACAAGGCCGGGAGGTGAAAATACTTCAGATAAACCCAACAAAAAG
  AAAAGGGGGGCCAATATGGCGCGAAATGGCGGAAACCGTAGGAAGAAAAATCCCTGGAGG
  GCGGAAATTGAAGATTTCTGGCTTCCCGGGGAATGCCAATATTTTGGGCCCCGGGGAGAG
  GGACCTTGCCGAGTGGGGCAGAAAAATTTCGGGGAGCGGGGTGGGGAAAAGTCCCACAGA
  ACTCCAACCAGGTTGGACGGTGTTTGACCAGAAATTGGTTGAGCGAGCCTAGGCTGCCTT
  GAGGGCGCN
  
• Restriction Sites: Please inquire
• ACCN: NM_001657
• Insert Size: 1300 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001657.2, NP_001648.1
• RefSeq Size: 1270 bp
• RefSeq ORF: 759 bp
• Locus ID: 374
• UniProt ID: P15514
• Cytogenetics: 4q13.3
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: ErbB signaling pathway
• Gene Summary: The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014]