SLC26A3 (NM_000111) Human Untagged Clone

CAT#: SC122548

SLC26A3 (untagged)-Human solute carrier family 26, member 3 (SLC26A3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SLC26A3
• Synonyms: CLD; DRA
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_000111 edited
  CCTGAGTGGATGGACACTGCCTCTTAGAACTAGAACTTAGAACTTTATCTTGAAAATGTA
  CCACTGTTGCAGAAGCTCCTCACAGAGTATGTGTCAGGCATTTTTAACCTGCTAAAGGCA
  AGAAGAAGTGTTCACCACATAGTTGCAAAGGTCTTCAACTTGCCACAGCCAACAGAAAAA
  TCAAAATGATTGAACCCTTTGGGAATCAGTATATTGTGGCCAGGCCAGTGTATTCTACAA
  ATGCTTTTGAGGAAAATCATAAAAAGACAGGAAGACATCATAAGACATTTCTGGATCATC
  TCAAAGTGTGTTGTAGCTGTTCCCCACAAAAGGCCAAGAGAATTGTCCTCTCTTTGTTCC
  CCATAGCATCTTGGTTGCCAGCATACCGGCTTAAAGAATGGTTGCTCAGTGATATTGTTT
  CTGGTATCAGCACAGGGATTGTGGCCGTACTACAAGGTTTAGCATTTGCTCTGCTGGTCG
  ACATTCCCCCAGTCTATGGGTTGTATGCATCCTTTTTCCCAGCCATAATCTACCTTTTCT
  TCGGCACTTCCAGACACATATCCGTGGGTCCGTTTCCGATTCTGAGTATGATGGTGGGAC
  TAGCAGTTTCAGGAGCAGTTTCAAAAGCAGTCCCAGATCGCAATGCAACTACTTTGGGAT
  TGCCTAACAACTCGAATAATTCTTCACTACTGGATGACGAGAGGGTGAGGGTGGCGGCGG
  CGGCATCAGTCACAGTGCTTTCTGGAATCATCCAGTTGGCTTTTGGGATTCTGCGGATTG
  GATTTGTAGTGATATACCTGTCTGAGTCCCTCATCAGTGGCTTCACTACTGCTGCTGCTG
  TTCATGTTTTGGTTTCCCAACTCAAATTCATTTTTCAGTTGACAGTCCCGTCACACACTG
  ATCCAGTTTCAATTTTCAAAGTACTATACTCTGTATTCTCACAAATAGAGAAGACTAATA
  TTGCAGACCTGGTGACAGCTCTGATTGTCCTTTTGGTTGTATCCATTGTTAAAGAAATAA
  ATCAGCGCTTCAAAGACAAACTTCCAGTGCCCATTCCAATCGAATTCATTATGACCGTGA
  TTGCAGCAGGTGTATCCTACGGCTGTGACTTTAAAAACAGGTTTAAAGTGGCTGTGGTTG
  GGGACATGAATCCTGGATTTCAGCCCCCTATTACACCTGACGTGGAGACTTTCCAAAACA
  CCGTAGGAGATTGCTTCGGCATCGCAATGGTTGCATTTGCAGTGGCCTTTTCAGTTGCCA
  GCGTCTATTCCCTCAAATACGATTATCCACTTGATGGCAATCAGGAGTTAATAGCCTTGG
  GACTGGGTAACATAGTCTGTGGAGTATTCAGAGGATTTGCTGGGAGTACTGCCCTCTCCA
  GATCAGCAGTTCAGGAGAGCACAGGAGGCAAAACACAGATTGCTGGGCTTATTGGTGCCA
  TCATCGTGCTGATTGTCGTTCTAGCCATTGGATTTCTCCTGGCGCCTCTACAAAAGTCCG
  TCCTGGCAGCTTTAGCATTGGGAAACTTAAAGGGAATGCTGATGCAGTTTGCTGAAATAG
  GCAGATTGTGGCGAAAGGACAAATATGATTGTTTAATTTGGATCATGACCTTCATCTTCA
  CCATTGTCCTGGGACTCGGGTTAGGCCTGGCAGCTAGTGTGGCATTTCAACTGCTAACCA
  TCGTGTTCAGGACCCAATTTCCAAAATGCAGCACGCTGGCTAATATTGGAAGAACCAACA
  TCTATAAGAATAAAAAAGATTATTATGATATGTATGAGCCAGAAGGAGTGAAAATTTTCA
  GATGTCCATCTCCTATCTACTTTGCAAACATTGGTTTCTTTAGGCGGAAACTTATCGATG
  CTGTTGGCTTTAGTCCACTTCGAATTCTACGCAAGCGCAACAAAGCTTTGAGGAAAATCC
  GAAAACTGCAGAAGCAAGGCTTGCTACAAGTGACACCAAAAGGATTTATATGTACTGTTG
  ACACCATAAAAGATTCTGACGAAGAGCTGGACAACAATCAGATAGAAGTACTGGACCAGC
  CAATCAATACCACAGACCTGCCTTTCCACATTGACTGGAATGATGATCTTCCTCTCAACA
  TTGAGGTCCCCAAAATCAGCCTCCACAGCCTCATTCTCGACTTTTCAGCAGTGTCCTTTC
  TTGATGTTTCTTCAGTGAGGGGCCTTAAATCGATTTTGCAAGAATTTATCAGGATCAAGG
  TAGATGTGTATATCGTTGGAACTGATGATGACTTCATTGAGAAGCTTAACCGGTATGAAT
  TTTTTGATGGTGAAGTGAAAAGCTCAATATTTTTCTTAACAATCCATGATGCTGTTTTGC
  ATATTTTGATGAAGAAAGATTACAGTACTTCAAAGTTTAATCCCAGTCAGGAAAAAGATG
  GAAAAATTGATTTTACCATAAATACAAATGGAGGATTACGTAATCGGGTATATGAGGTGC
  CAGTTGAAACAAAATTCTAATCAACATATAATTCAGAAGGATCTTCATCTGACTATGACA
  TAAAAACAACTTTATACCCAGAAAGTTATTGATAAGTTCATACATTGTACGAAGAGTATT
  TTTGACAGAATATGTTTCAAACTTTGGAACAAGATGGTTCTAGCATGGCATATTTTTCAC
  ATATCTAGTATGAAATTATATAAGTATTCTAAATTTTATATCTTGTAGCTTTATCAAAGG
  GTGAAAATTATTTTGTTCATACATATTTTTGTAGCACTGACAGATTTCCATCCTAGTCAC
  TACCTTCATGCATAGGTTTAGCAGTATAGTGGCGCCACTGTTTTGAATCTCATAATTTAT
  ACAGGTCATATTAATATATTTCCATTAAAAAATCAGTTGTACAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000111 unedited
  GGTTTGGTTTTGTATACGACTTATATAGGCGGCCGCGNATTCAGATCTGGTACCGGTCCG
  GAATTCCCGGGATCCTGAGTGGATGGACACTGCCTCTTAGAACTAGAACTTAGAACTTTA
  TCTTGAAAATGTACCACTGTTGCAGAAGCTCCTCACAGAGTATGTGTCAGGCATTTTTAA
  CCTGCTAAAGGCAAGAAGAAGTGTTCACCACATAGTTGCAAAGGTCTTCAACTTGCCACA
  GCCAACAGAAAAATCAAAATGATTGAACCCTTTGGGAATCAGTATATTGTGGCCAGGCCA
  GTGTATTCTACAAATGCTTTTGAGGAAAATCATAAAAAGACAGGAAGACATCATAAGACA
  TTTCTGGATCATCTCAAAGTGTGTTGTAGCTGTTCCCCACAAAAGGCCAAGAGAATTGTC
  CTCTCTTTGTTCCCCATAGCATCTTGGTTGCCAGCATACCGGCTTAAAGAATGGTTGCTC
  AGTGATATTGTTTCTGGTATCAGCACAGGGATTGTGGCCGTACTACAAGGTTTAGCATTT
  GCTCTGCTGGTCGACATTCCCCCAGTCTATGGGTTGTATGCATCCTTTTTCCCAGCCATA
  ATCTACCTTTTCTTCGGCACTTCCAGACACATATCCGTGGGTCCGTTTCCGATTCTGAGT
  ATGATGGTGGGACTAGCAGTTTCAGGAGCAGTTTCAAAAGCAGTCCCAGATCGCAATGCA
  ACTACTTTGGGATTGCCTAACAACTCGAATAATTCTTCACTACTGGATGACNAGAGGGTG
  AGGGTGGCGGCGGCGGCATCAGTCACAGTGCTTTCTGGAATCATCCAGTTGGCTTTTGGG
  ATTCTGCGGATTGGATTTGTAGTGATATACCTGTCTGAGTCCCTCATCAGTGGCTTCACT
  ACTGCTGCTGCTNGTCATGTTTTGGTTN
  
• Restriction Sites: Please inquire
• ACCN: NM_000111
• Insert Size: 2955 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000111.1, NP_000102.1
• RefSeq Size: 2881 bp
• RefSeq ORF: 2295 bp
• Locus ID: 1811
• UniProt ID: P40879
• Cytogenetics: 7q22.3-q31.1
• Protein Families: Druggable Genome, Transcription Factors, Transmembrane
• Gene Summary: The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea. [provided by RefSeq, Oct 2008]