ALDH3B1 (NM_000694) Human Untagged Clone

CAT#: SC119707

ALDH3B1 (untagged)-Human aldehyde dehydrogenase 3 family, member B1 (ALDH3B1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ALDH3B1
• Synonyms: ALDH4; ALDH7
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119707 sequence for NM_000694 edited (data generated by NextGen Sequencing)
  ATGGACCCCCTTGGGGACACGCTGCGGCGACTGCGGGAGGCCTTCCACGCGGGGCGCACG
  CGGCCAGCTGAGTTCCGGGCTGCGCAGCTCCAAGGCCTGGGCCGCTTCCTGCAAGAAAAC
  AAGCAGCTTCTGCACGACGCACTGGCCCAGGACCTGCACAAGTCAGCCTTCGAGTCGGAG
  GTGTCTGAGGTTGCCATCAGCCAGGGCGAGGTCACCCTGGCCCTCAGGAACCTCCGGGCC
  TGGATGAAGGACGAGCGTGTGCCCAAGAACCTGGCCACGCAGCTGGACTCCGCCTTCATC
  CGGAAGGAGCCCTTTGGCCTGGTCCTCATCATTGCGCCCTGGAACTATCCGCTGAACCTG
  ACGCTGGTGCCCCTCGTGGGAGCCCTCGCTGCAGGGAACTGTGTGGTGCTGAAGCCATCG
  GAGATTAGCAAGAACGTCGAGAAGATCCTGGCCGAGGTGCTGCCCCAATACGTGGACCAG
  AGCTGCTTTGCTGTGGTGCTGGGCGGGCCCCAGGAGACGGGGCAGCTGCTAGAGCACAGG
  TTCGACTACATCTTCTTCACAGGGAGCCCTCGTGTGGGCAAGATTGTTATGACTGCTGCC
  GCCAAGCACCTGACACCTGTCACCCTGGAGCTGGGGGGCAAGAACCCTTGCTACGTGGAC
  GACAACTGCGACCCCCAGACCGTGGCCAACCGCGTGGCCTGGTTCCGCTACTTCAACGCC
  GGCCAGACCTGCGTGGCCCCCGACTATGTCCTATGCAGCCCTGAGATGCAGGAGAGGCTG
  CTGCCTGCCCTGCAGAGCACCATCACCCGTTTCTATGGCGACGACCCCCAGAGCTCCCCA
  AACCTGGGCCGCATCATCAACCAGAAACAGTTCCAGCGGCTGCGGGCATTGCTGGGCTGC
  GGCCGTGTGGCCATTGGGGGCCAGAGCGATGAGAGCGATCGCTACATCGCCCCCACGGTG
  CTGGTGGATGTGCAGGAGATGGAGCCTGTGATGCAGGAGGAGATCTTCGGGCCCATCCTG
  CCCATCGTGAACGTGCAGAGCTTGGACGAGGCCATCGAGTTCATCAACCGGCGGGAGAAG
  CCCCTGGCCCTGTACGCCTTCTCCAACAGCAGCCAGGTGGTCAAGCGGGTGCTGACCCAG
  ACCAGCAGTGGGGGCTTCTGTGGGAACGACGGCTTCATGCACATGACCCTGGCCAGCCTG
  CCTTTTGGAGGAGTGGGTGCCAGTGGGATGGGCCGGTACCATGGCAAGTTCTCCTTCGAC
  ACCTTCTCCCACCATCGCGCCTGCCTCCTGCGCAGCCCGGGGATGGAGAAGCTCAACGCC
  CTCCGCTACCCGCCGCAATCGCCGCGCCGCCTGAGGATGCTGCTGGTGGCCATGGAGGCC
  CAAGGCTGCAGCTGCACACTGCTCTGA
  
  Clone variation with respect to NM_000694.2
  747 c=>t;1149 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000694 unedited
  GGGGGGGGGGNNNNNNNNCNNNNNNNNNNTGTTCAGATTTGTATACGACTCACTATAGGC
  GGCCGCGAATTCGCACCAGCTTGGCAGAGCCTCAGGATGGACCCCCTTGGGGACACGCTG
  CGGCGACTGCGGGAGGCCTTCCACGCGGGGCGCACGCGGCCAGCTGAGTTCCGGGCTGCG
  CAGCTCCAAGGCCTGGGCCGCTTCCTGCAAGAAAACAAGCAGCTTCTGCACGACGCACTG
  GCCCAGGACCTGCACAAGTCAGCCTTCGAGTCGGAGGTGTCTGAGGTTGCCATCAGCCAG
  GGCGAGGTCACCCTGGCCCTCAGGAACCTCCGGGCCTGGATGAAGGACGAGCGTGTGCCC
  AAGAACCTGGCCACGCAGCTGGACTCCGCCTTCATCCGGAAGGAGCCCTTTGGCCTGGTC
  CTCATCATTGCGCCCTGGAACTATCCGCTGAACCTGACGCTGGTGCCCCTCGTGGGAGCC
  CTCGCTGCAGGGAACTGTGTGGTGCTGAAGCCATCGGAGATTAGCAAGAACGTCGAGAAG
  ATCCTGGCCGAGGTGCTGCCCCAATACGTGGACCAGAGCTGCTTTGCTGTGGTGCTGGGC
  GGGCCCCAGGAGACGGNGCAGCTGCTAGAGCACAGGTTCGACTACATCTTCTTCACAGGG
  AGCCCTCGTGTGGGCAAGATTGTTATGACTGCTGCCGCCAAGCACCTGACACCTGTCACC
  CTGGAGCTGGGNGGGCAAGAACCCTTGCTACGTGGACGACAACTGCGACCCCCAGACCGT
  GCCAACCGCGTGGGCCTGGTTCCGCTACTTCAACGCCGGCCAGACCTGCGTGGCCCCCGA
  CTATGTCCTATGCACCCCTGAAATGCANNGAAAGGCTGCTGCCTGCCCTGCAGAGCACAT
  CACCCGTTTCTAGGGCGACGACCCCCAAAGCTNCCCCAACT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000694
• Insert Size: 2750 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000694.2, NP_000685.1
• RefSeq Size: 2857 bp
• RefSeq ORF: 1407 bp
• Locus ID: 221
• UniProt ID: P43353
• Cytogenetics: 11q13.2
• Domains: aldedh
• Protein Families: Druggable Genome
• Protein Pathways: Drug metabolism - cytochrome P450, Glycolysis / Gluconeogenesis, Histidine metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Phenylalanine metabolism, Tyrosine metabolism
• Gene Summary: This gene encodes a member of the aldehyde dehydrogenase protein family. Aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The encoded protein is able to oxidize long-chain fatty aldehydes in vitro, and may play a role in protection from oxidative stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
  Transcript Variant: This variant (1) encodes the longest isoform (a). Variants 1 and 3 encode the same isoform.