ALDH1A3 (NM_000693) Human Untagged Clone

SKU SC119706

ALDH1A3 (untagged)-Human aldehyde dehydrogenase 1 family, member A3 (ALDH1A3)

Product Data

• Type: Human Untagged Clone
• Target Symbol: ALDH1A3
• Synonyms: ALDH1A6; ALDH6; MCOP8; RALDH3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_000693 edited; ATGGCCACCGCTAACGGGGCCGTGGAAAACGGGCAGCCGGACAGGAAGCCGCCGGCCCTG; CCGCGCCCCATCCGCAACCTGGAGGTCAAGTTCACCAAGATATTTATCAACAATGAATGG; CACGAATCCAAGAGTGGGAAAAAGTTTGCTACATGTAACCCTTCAACTCGGGAGCAAATA; TGTGAAGTGGAAGAAGGAGATAAGCCCGACGTGGACAAGGCTGTGGAGGCTGCACAGGTT; GCCTTCCAGAGGGGCTCGCCATGGCGCCGGCTGGATGCCCTGAGTCGTGGGCGGCTGCTG; CACCAGCTGGCTGACCTGGTGGAGAGGGACCGCGCCACCTTGGCCGCCCTGGAGACGATG; GATACAGGGAAGCCATTTCTTCATGCTTTTTTCATCGACCTGGAGGGCTGTATTAGAACC; CTCAGATACTTTGCAGGGTGGGCAGACAAAATCCAGGGCAAGACCATCCCCACAGATGAC; AACGTCGTGTGCTTCACCAGGCATGAGCCCATTGGTGTCTGTGGGGCCATCACTCCATGG; AACTTCCCCCTGCTGATGCTGGTGTGGAAGCTGGCACCCGCCCTCTGCTGTGGGAACACC; ATGGTCCTGAAGCCTGCGGAGCAGACACCTCTCACCGCCCTTTATCTCGGCTCTCTGATC; AAAGAGGCCGGGTTCCCTCCAGGAGTGGTGAACATTGTGCCAGGATTCGGGCCCACAGTG; GGAGCAGCAATTTCTTCTCACCCTCAGATCAACAAGATCGCCTTCACCGGCTCCACAGAG; GTTGGAAAACTGGTTAAAGAAGCTGCGTCCCGGAGCAATCTGAAGCGGGTGACGCTGGAG; CTGGGGGGGAAGAACCCCTGCATCGTGTGTGCGGACGCTGACTTGGACTTGGCAGTGGAG; TGTGCCCATCAGGGAGTGTTCTTCAACCAAGGCCAGTGTTGCACGGCAGCCTCCAGGGTG; TTCGTGGAGGAGCAGGTCTACTCTGAGTTTGTCAGGCGGAGCGTGGAGTATGCCAAGAAA; CGGCCCGTGGGAGACCCCTTCGATGTCAAAACAGAACAGGGGCCTCAGATTGATCAAAAG; CAGTTCGACAAAATCTTAGAGCTGATCGAGAGTGGGAAGAAGGAAGGGGCCAAGCTGGAA; TGCGGGGGCTCAGCCATGGAAGACAAGGGGCTCTTCATCAAACCCACTGTCTTCTCAGAA; GTCACAGACAACATGCGGATTGCCAAAGAGGAGATTTTCGGGCCAGTGCAACCAATACTG; AAGTTCAAAAGTATCGAAGAAGTGATAAAAAGAGCGAATAGCACCGACTATGGACTCACA; GCAGCCGTGTTCACAAAAAATCTCGACAAAGCCCTGAAGTTGGCTTCTGCCTTAGAGTCT; GGAACGGTCTGGATCAACTGCTACAACGCCCTCTATGCACAGGCTCCATTTGGTGGCTTT; AAAATGTCAGGAAATGGCAGAGAACTAGGTGAATACGCTTTGGCCGAATACACAGAAGTG; AAAACTGTCACCATCAAACTTGGCGACAAGAACCCCTGA;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000693 unedited; GCCGCGAATTCGGCACGAGAGCCGGTGCGCCGCAGACTAGGGCGCCTCGGGCCAGGGAGC; GCGGAGGAGCCATGGCCACCGCTAACGGGGCCGTGGAAAACGGGCAGCCGGACAGGAAGC; CGCCGGCCCTGCCGCGCCCCATCCGCAACCTGGAGGTCAAGTTCACCAAGATATTTATCA; ACAATGAATGGCACGAATCCAAGAGTGGGAAAAAGTTTGCTACATGTAACCCTTCAACTC; GGGAGCAAATATGTGAAGTGGAAGAAGGAGATAAGCCCGACGTGGACAAGGCTGTGGAGG; CTGCACAGGTTGCCTTCCAGAGGGGCTCGCCATGGCGCCGGCTGGATGCCCTGAGTCGTG; GGCGGCTGCTGCACCAGCTGGCTGACCTGGTGGAGAGGGACCGCGCCACCTTGGCCGCCC; TGGAGACGATGGATACAGGGAAGCCATTTCTTCATGCTTTTTTCATCGACCTGGAGGGCT; GTATTAGAACCCTCAGATACTTTGCAGGGTGGGCAGACAAAATCCAGGGCAAGACCATCC; CCACAGATGACAANCGTCGTGTGCTTCACCAGGCATGAGCCCATTGGTGTCTGTGGGGCC; ATCACTCCATGGGAACTTCCCCTGCTGATGCTGGTGTGGAAGCTGGCACCCGCCCTCTGC; TGTGGGAACACCATGGTCCTGAAGCCTGCGGAGCAGACACCTCTCACCGCCCTTTATCTC; G;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000693 unedited; AGCTCTGNNACCGCGGCCGCATNCTAGNGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTT; TTTTTTTCTCAAATATCCAATTTTATTTTATCATTCTCGCATTGGGGGATGCGATCTGCA; GCTAGGATCGGAATTCCCAGGCCTATAGATTTTTAAACCACACCACAGGGGTAAACCTTA; AAAAAAGGGAAACCTAACACTATATATATTTCCATTTCTAAATACAGTATATTACAGAAG; TTTAAATATACCACCTTTGGGTACTTACAACTATAAAAAGATACAATAACTCTACCAATT; ATAAATAATGTAGCATTTCATATTAAAGACATTATCGTACAATGGAAAAATAGGAACCCT; CTAACGTATCACTATCAAGGTTAGGGTCTATATCTACTTGAGATAAAATACTGAAAATTC; AGGGTATGAAGCCAAATCCTGATTTAACAAGTTATTGGTAGTATAAGGGATAAGGGTTAG; CTGATGAAGGGAAGGCAAATGTGGTAATTTATATCTCTGACAAGGGTGATAGGCCCATTT; TATACATGGTTTTCGTTATACACACACTGGTTCTGTTACGGGCCCTCATTTTATTATTGC; CCTCCCCAACTTAATTTGCAAACTTAAGCACTACTTTCCCCATAGGAAAGTCCTAGTTAG; TACCCATAAAAGTATCCGCCGGATAACACATTGGTTTTTGTTTTTGAAGCTTTTGGGGAC; CCTTTAAGTTTCCAAGGTAAAACTGAAAATGCCCACATCTTTGGGACCCCCAAGAGAAAA; AAAAATTCCACCCTGCCGGGGAAAATTCGGGCCCTTGGAGAAGACCGAGGCCTCCTAAAA; CCGGGGGTTTTACTACCTCTCAAATTAATTCAAACGGCCTAAAATAACGGGGTGGTTATC; CGCCACCTTTCCCGGGGGCCCCTTCCAAATCAATGG;
• Restriction Sites: NotI-NotI
• ACCN: NM_000693
• Insert Size: 3200 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_000693.1, NP_000684.1
• RefSeq Size: 3442 bp
• RefSeq ORF: 1539 bp
• Locus ID: 220
• UniProt ID: P47895
• Cytogenetics: 15q26.3
• Domains: aldedh
• Protein Families: Druggable Genome
• Protein Pathways: Drug metabolism - cytochrome P450, Glycolysis / Gluconeogenesis, Histidine metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Phenylalanine metabolism, Tyrosine metabolism
• Summary: This gene encodes an aldehyde dehydrogenase enzyme that uses retinal as a substrate. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]; Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).