ALDH1B1 (NM_000692) Human Untagged Clone

SKU SC119705

ALDH1B1 (untagged)-Human aldehyde dehydrogenase 1 family, member B1 (ALDH1B1), nuclear gene encoding mitochondrial protein

Product Data

• Type: Human Untagged Clone
• Target Symbol: ALDH1B1
• Synonyms: ALDH5; ALDHX
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119705 sequence for NM_000692 edited (data generated by NextGen Sequencing); ATGCTGCGCTTCCTGGCACCCCGGCTGCTTAGCCTCCAGGGCAGGACCGCCCGCTACTCC; TCGGCAGCAGCCCTCCCAAGCCCCATTCTGAACCCAGACATCCCCTACAACCAGCTGTTC; ATCAACAATGAATGGCAAGATGCAGTCAGCAAGAAGACCTTCCCGACGGTCAACCCTACC; ACCGGGGAGGTCATCGGGCACGTGGCTGAAGGTGACCGGGCTGATGTGGATCGGGCCGTG; AAAGCAGCCCGGGAAGCCTTCCGCCTGGGGTCCCCATGGCGCCGGATGGATGCCTCTGAG; CGGGGCCGGCTGCTGAACCGCCTGGCAGACCTAGTGGAGCGGGATCGAGTCTACTTGGCC; TCACTCGAGACCTTGGACAATGGGAAGCCTTTCCAAGAGTCTTACGCCTTGGACTTGGAT; GAGGTCATCAAGGTGTATCGGTACTTTGCTGGCTGGGCTGACAAGTGGCATGGCAAGACC; ATCCCCATGGATGGCCAGCATTTCTGCTTCACCCGGCATGAGCCCGTTGGTGTCTGTGGC; CAGATCATCCCGTGGAACTTCCCCTTGGTCATGCAAGGTTGGAAACTTGCCCCGGCACTC; GCCACAGGCAACACTGTGGTTATGAAGGTGGCAGAGCAGACCCCCCTCTCTGCCCTGTAT; TTGGCCTCCCTCATCAAGGAGGCAGGCTTTCCCCCTGGGGTGGTGAACATCATCACGGGG; TATGGCCCAACAGCAGGTGCGGCCATCGCCCAGCACATGGATGTTGACAAAGTTGCCTTC; ACCGGTTCCACCGAGGTGGGCCACCTGATCCAGAAAGCAGCTGGCGATTCCAACCTCAAG; AGAGTCACCCTGGAGCTGGGTGGTAAGAGCCCCAGCATCGTGCTGGCCGATGCTGACATG; GAGCATGCCGTGGAGCAGTGCCACGAAGCCCTGTTCTTCAACATGGGCCAGTGCTGCTGT; GCTGGCTCCCGGACCTTCGTGGAAGAATCCATCTACAATGAGTTTCTCGAGAGAACCGTG; GAGAAAGCAAAGCAGAGGAAAGTGGGGAACCCCTTTGAGCTGGACACCCAGCAGGGGCCT; CAGGTGGACAAGGAGCAGTTTGAACGAGTCCTAGGCTACATCCAGCTTGGCCAGAAGGAG; GGCGCAAAACTCCTCTGTGGCGGAGAGCGTTTCGGGGAGCGTGGTTTCTTCATCAAGCCT; ACTGTCTTTGGTGGCGTGCAGGATGACATGAGAATTGCCAAAGAGGAGATCTTTGGGCCT; GTGCAGCCCCTGTTCAAGTTCAAGAAGATTGAGGAGGTGGTTGAGAGGGCCAACAACACC; AGGTATGGCCTGGCTGCGGCTGTGTTCACCCGGGATCTGGACAAGGCCATGTACTTCACC; CAGGCACTCCAGGCCGGGACCGTGTGGGTAAACACCTACAACATCGTCACCTGCCACACG; CCATTTGGAGGGTTTAAGGAATCTGGAAACGGGAGGGAGCTGGGTGAGGATGGGCTTAAG; GCCTACACAGAGGTAAAGACGGTCACCATCAAGGTTCCTCAGAAGAACTCGTAA; ; Clone variation with respect to NM_000692.4; 195 t=>c;576 g=>a;757 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000692 unedited; TCGGCACCAGCGGAGCCCCAGCCTGCTGCAAAGTGTCAGCATGCTGCGCTTCCTGGCACC; CCGGCTGCTTANCCTCCAGGGCAGGACCGCCCGCTACTCCTCGGCAGCAGCCCTCCCAAG; CCCCATTCTGAACCCAGACATCCCCTACAACCAGCTGTTCATCAACAATGAATGGCAAGA; TGCAGTCANCAAGAAGACCGGTGCCGACGGTCAACCCTACCACCGGGGAGGTCATCGGGC; ACGTGGCTGAAGGTGACCGGGCTGATGTGGATCGGGCCNTGAAAGCGACCCGGGAAGCCT; TCCGCCTGGGGTCCCCATGGCGCCGGATGGATGCCTCTGAGCGGGGCCGGCTGCTGAACC; GCCTGGCAAACCTAGTGGAGCGGGATCGAGTCTACTTGGCCTCACTCNAGACCTGGGACA; ATGGGAACCCTTTCCAAGAATCTTACGCCTTGGACTTGGATGAAGGCATCAAGGGGTATC; GGTACTTTGCTGGCTGGGCTGACAAGGGGCATGGCAAGACCATCCGCATGGATGGGCAGC; ATTTCTGCGTCACCCGGCATGAGCCCGTTGGGTGTCTGGGGCCAAATCAATCCCGTGGAA; CTTTCCCCTGGGTCCATCCAGGGGTNGAAACTTTGGCCCCGGACTCNNCCACAGGCAACA; CTGGGGGGTATTGAAGGGGGCAAACAAACCCCCCCTTTTTGCCTGGATTTTGGCCTCCCT; CTCAAGGAAGGAAGGCTTTCCCCCTGGGGGGGGAACATAATCACGGGGGGATGGCCCAAC; ACGAGGGCGCGGCCTCCCCCAACCATA;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000692 unedited; AACCTGNGTGTTACGTGTATTTTTTAACGGNGTTAATGATGGCCGGGTGTTGTGGCTCCC; ACTCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGATCACCTGAGGTCAGGAGTT; CAAGATCAGCCTGGCCAAAATGGTGAAACCTCATCTCTACTAAAAATACAAAAATTAGCC; AGGTGTGATGGCATGTACCTATAATCCCAGCTACTCAGGAGGCTGAGACAGGAGAATCGC; TTGAATCTGGGAGGCGGAGGTTGCAGTGAGACGAGATCACACCACTGCACTCCAGCCTGG; GCGACAGAGTGAGACTCCGTGTCAAAAAAAAAAAAAAAAAAGAAAAAAAGAAAGAAATTA; ATTCATATACCATAATTAAACAATTCCATAGTTTTTAGTATTTTTACCAAATCATGCAAC; CATTACTATTGTTCAACTCCAGAACATTTTCAAAACCTCCCAAAAACAAATCCCATGCCC; ACTAACAATTACTCCTCTATCCCCTGGCAACCACTAATCTATGTTCCATCTCCATGGATT; TGCCTAGTATGTATATTTCATATAAATGGAATCATACAGTCTGTAGCCTTGTACATCTCT; CTGGCTTGTTTCACTGAGAAGGATGTTTTCAGGGTTCACTGATGTCACAGCATGTGTCAG; TACTTCATTCCTTTTATGGGTGAGTAATCCAAGGATTTTCCATGGGAAACATTTATTAAT; CCACTCTCAATTGACGGCATTTGGGATGTTTGGGCTTTCTTTACAGTGTAAACAGGGAAC; ATATTTTTGGCCTCCCNCTTCCCCAATTAAGGAAATCAATGCCAAGGAAGGGCAGCACTT; AACCACCGCACTGGCCACAAACAGGGAAGCCCCTTGGTTTAAGGTTAACCCAGAAAAATG; GGGCCACGTTTATTTCCCCCCCC;
• Restriction Sites: NotI-NotI
• ACCN: NM_000692
• Insert Size: 3000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_000692.3, NP_000683.3
• RefSeq Size: 3044 bp
• RefSeq ORF: 1554 bp
• Locus ID: 219
• UniProt ID: P30837
• Cytogenetics: 9p13.1
• Domains: aldedh
• Protein Families: Druggable Genome
• Protein Pathways: Arginine and proline metabolism, Ascorbate and aldarate metabolism, beta-Alanine metabolism, Butanoate metabolism, Fatty acid metabolism, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, leucine and isoleucine degradation, Limonene and pinene degradation, Lysine degradation, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Valine
• Summary: This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems. [provided by RefSeq, Jul 2008]