CBR3 (NM_001236) Human Untagged Clone

CAT#: SC119368

CBR3 (untagged)-Human carbonyl reductase 3 (CBR3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CBR3
• Synonyms: hCBR3; HEL-S-25; SDR21C2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119368 sequence for NM_001236 edited (data generated by NextGen Sequencing)
  ATGTCGTCCTGCAGCCGCGTGGCGCTGGTGACCGGGGCCAACAGGGGCATCGGCTTGGCC
  ATCGCGCGCGAACTGTGCCGACAGTTCTCTGGGGATGTGGTGCTCACCGCGCGGGACGTG
  GCGCGGGGCCAGGCGGCCGTGCAGCAGCTGCAGGCGGAGGGCCTGAGCCCGCGCTTCCAC
  CAACTGGACATCGACGACTTGCAGAGCATCCGCGCCCTGCGCGACTTCCTGCGCAAGGAG
  TACGGGGGGCTCAATGTACTGGTCAACAACGCGGCCGTCGCCTTCAAGAGTGATGATCCA
  ATGCCCTTTGACATTAAAGCTGAGATGACACTGAAGACAAATTTTTTTGCCACTAGAAAC
  ATGTGCAACGAGTTACTGCCGATAATGAAACCTCATGGGAGAGTGGTGAATATCAGTAGT
  TTGCAGTGTTTAAGGGCTTTTGAAAACTGCAGTGAAGATCTGCAGGAAAGGTTCCACAGT
  GAGACACTCACAGAAGGAGACCTGGTGGATCTCATGAAAAAGTTTGTGGAGGACACAAAA
  AATGAGGTGCATGAGAGGGAAGGCTGGCCCAACTCACCTTATGGGGTGTCCAAGTTGGGG
  GTCACAGTCTTATCGAGGATCCTGGCCAGGCGTCTGGATGAGAAGAGGAAAGCTGACAGG
  ATTCTGGTGAATGCGTGCTGCCCAGGACCAGTGAAGACAGACATGGATGGGAAAGACAGC
  ATCAGGACTGTGGAGGAGGGGGCTGAGACCCCTGTCTACTTGGCCCTCTTGCCTCCAGAT
  GCCACTGAGCCACAAGGCCAGTTGGTCCATGACAAAGTTGTGCAAAACTGGTAA
  
  Clone variation with respect to NM_001236.3
  255 c=>t;606 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001236 unedited
  CCGCAACTCGTTAATTGTAAACGATTTACTATAGGCGGCCGCGNAATTCGCACGAGGACA
  CTAGCTGGGCTCCTCGGGGCGCGCCCCAGTGGTCCGAAGCCCGGTCCGCCCTCCACGCAG
  GTGCCCCGCGCTCCCCGCTCAGCCATGTCGTCCTGCAGCCGCGTGGCGCTGGTGACCGGG
  GCCAACAGGGGCATCGGCTTGGCCATCGCGCGCGAACTGTGCCGACAGTTCTCTGGGGAT
  GTGGTGCTCACCGCGCGGGACGTGGCGCGGGGCCAGGCGGCCGTGCAGCAGCTGCAGGCG
  GAGGGCCTGAGCCCGCGCTTCCACCAACTGGACATCGACGACTTGCAGAGCATCCGCGCC
  CTGCGCGACTTCCTGCGCAAGGAGTACGGGGGGCTCAATGTACTGGTCAACAACGCGGCC
  GTCGCCTTCAAGAGTGATGATCCAATGCCCTTTGACATTAAAGCTGAGATGACACTGAAG
  ACAAATTTTTTTGCCACTAGAAACATGTGCAACGAGTTACTGCCGATAATGAAACCTCAT
  GGGAGAGTGGTGAATATCAGTAGTTTGCAGTGTTTAAGGGCTTTTGAAAACTGCAGTGAA
  GATCTGCAGGAAAGGTTCCACAGTGAGACACTCACAGAAGGAGACCTGGTGGATCTCATG
  AAAAAGTTTGTGGAGGACACAAAAAATGAGGTGCATGAGAGGGAAGGCTGGCCCAACTCA
  CCTTATGGGGTGTCCAAGTTGGGGGTCACAGNTCTTATCGAGATCCTGGGCCAGCGTCTG
  GATGAGAAGAGGAAAGCTGACAGGATTCTGGTGAATGCGTGCTGCCCAGGACCAGTGAAG
  ACAGACATGGATGGGAAAGACACTCGNGCCCTTGTGGAGGAAGGGGGCTGAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001236
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001236.3, NP_001227.1
• RefSeq Size: 1128 bp
• RefSeq ORF: 834 bp
• Locus ID: 874
• UniProt ID: O75828
• Cytogenetics: 21q22.12
• Protein Families: Druggable Genome
• Protein Pathways: Arachidonic acid metabolism, Metabolic pathways
• Gene Summary: Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq, Jul 2008]