D Amino Acid Oxidase (DAO) (NM_001917) Human Untagged Clone

SKU SC118941

DAO (untagged)-Human D-amino-acid oxidase (DAO)

Product Data

• Type: Human Untagged Clone
• Target Symbol: D Amino Acid Oxidase
• Synonyms: DAAO; DAMOX; OXDA
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC118941 sequence for NM_001917 edited (data generated by NextGen Sequencing); ATGCGTGTGGTGGTGATTGGAGCAGGAGTCATCGGGCTGTCCACCGCCCTCTGCATCCAT; GAGCGCTACCACTCAGTCCTGCAGCCACTGGACATAAAGGTCTACGCGGACCGCTTCACC; CCACTCACCACCACCGACGTGGCTGCCGGCCTCTGGCAGCCCTACCTTTCTGACCCCAAC; AACCCACAGGAGGCGGACTGGAGCCAACAGACCTTTGACTATCTCCTGAGCCATGTCCAT; TCTCCCAACGCTGAAAACCTGGGCCTGTTCCTAATCTCGGGCTACAACCTCTTCCATGAA; GCCATTCCGGACCCTTCCTGGAAGGACACAGTTCTGGGATTTCGGAAGCTGACCCCCAGA; GAGCTGGATATGTTCCCAGATTACGGCTATGGCTGGTTCCACACAAGCCTAATTCTGGAG; GGAAAGAACTATCTACAGTGGCTGACTGAAAGGTTAACTGAGAGGGGAGTGAAGTTCTTC; CAGCGGAAAGTGGAGTCTTTTGAGGAGGTGGCAAGAGAAGGCGCAGACGTGATTGTCAAC; TGCACTGGGGTATGGGCTGGGGCGCTACAACGAGACCCCCTGCTGCAGCCAGGCCGGGGG; CAGATCATGAAGGTGGACGCCCCTTGGATGAAGCACTTCATTCTCACCCATGACCCAGAG; AGAGGCATCTACAATTCCCCGTACATCATCCCAGGGACCCAGACAGTTACTCTTGGAGGC; ATCTTCCAGTTGGGAAACTGGAGTGAACTAAACAATATCCAGGACCACAACACCATTTGG; GAAGGCTGCTGCAGACTGGAGCCCACACTGAAGAATGCAAGAATTATTGGTGAACGAACT; GGCTTCCGGCCAGTACGCCCCCAGATTCGGCTAGAAAGAGAACAGCTTCGCACTGGACCT; TCAAACACAGAGGTCATCCACAACTATGGCCATGGAGGCTACGGGCTCACCATCCACTGG; GGATGTGCCCTGGAGGCAGCCAAGCTCTTTGGGAGAATCCTGGAAGAAAAGAAATTGTCC; AGAATGCCACCATCCCACCTCTGA; ; Clone variation with respect to NM_001917.4;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001917 unedited; AGGATTTGTATACGACTTCTATAGGGCGGCCGCGAATTCGCACGAGGGAGATCCAGCCTC; TCAAACATCCAGCAGAGAGACCATAGGCTGCTGCAATGCGTGTGGTGGTGATTGGAGCAG; GAGTCATCGGGCTGTCCACCGCCCTCTGCATCCATGAGCGCTACCACTCAGTCCTGCAGC; CACTGGACATAAAGGTCTACGCGGACCGCTTCACCCCACTCACCACCACCGACGTGGCTG; CCGGCCTCTGGCAGCCCTACCTTTCTGACCCCAACAACCCACAGGAGGCGGACTGGAGCC; AACAGACCTTTGACTATCTCCTGAGCCATGTCCATTCTCCCAACGCTGAAAACCTGGGCC; TGTTCCTAATCTCGGGCTACAACCTCTTCCATGAAGCCATTCCGGACCCTTCCTGGAAGG; ACACAGTTCTGGGATTTCGGAAGCTGACCCCCAGAGAGCTGGATATGTTCCCAGATTACG; GCTATGGCTGGTTCCACACAAGCCTAATTCTGGAGGGAAAGAACTATCTACAGTGGCTGA; CTGAAAGGTTAACTGAGAGGGGAGTGAAGTTCTTCCAGCGGAAAGTGGAGTCTTTTGAGG; AGGTGGCAAGAGAAGGCGCAGACGTGATTGTCAACTGCACTGGGGTATGGGCTGGGGCGC; TACAACGAGACCCCCTGCTGCAGCCCAGCCCNGGGGCAGATCATGAAAGTGGACGCCCCT; TGGATGAAGCACTTTATTCTCACCCATGACCCCAGAGAGAAGCATCTACCATTCCCCCGT; ACATCATCCCCAGGACCCAGACAGTTACTCTTGGAGGCATCCTCCAGTTGGGAAACTGGA; GTGAACTAAACATATCCAGGACCACACACCATTTGTGGAAGCTGCTGCAGACTGAAGCCC; AACTGAAGATGCCAGATNTATTGGTGACGAACTGGCTTCCTCCCATCC;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001917 unedited; CGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTGCAGGACTTTTCAGAACCTTT; AATATGTTAGTACAACTTGTAATCAGGTTACTTAGCCTCAATTATCCTCCATTTTCTGTG; GCTCTGGGCAGTTGGCCTCTTTGATTTTCTGAGCTGTCCTTTCTTCTGAAGACTCATGGA; ATGACAGCCTCAGCTGTTCTTTATAATGCCAGACCCAGAGAAGGTAGAGGGATTTCAGTG; ATGAGAGGGGCCCCATGTTGGGCTGAACCCTTCTCCAGGCACTGACTTTGTGGCTTTCTC; TCACCTCATGCTTCTTTGAGGAAAGAAGTGAGGGAGAAGCAATGGCTTATGAAGGAGCAC; ATTGATTCATTGGCTGAGGGGAGAAGGGAGTTCTTGTGGGGGGAGGCAGCAGTCACTGGA; GTCTTCAGAGGTGGGATGGTGGCATTCTGGACAATTTCTTTTCTTCCAGGATTCTCCCAA; AGAGCTTGGCTGCCTCCAGGGCACATCCCCAGTGGATGGTGAGCCCGTAGCCTCCATGGC; CATAGTTGTGGATGACCTCTGTGTTTGAAGGTCCAGTGCGAAGCTGTTCTCTTTCTAGCC; GAATCTGGGGGCGTACTGGCCGGAAGCCAGTTCGTTCACCAATAATTCTTGCATTCTTCA; GTGTGGGCTCCAGTCTGCAGCAGCCTTCCCAAATGGTGTTGTGGTCCTGGATATTGTTTA; GTTCACTCCAGTTTCCCAACTGGAAGATGCCTCCAAGAGTAACTGTCTGGGTCCCTGGGA; TGATGTACGGGGCATTGTAAATGCCTCTCTCTGGCTCATGGGTGAGAATGAAGTGCTTCT; CCCAGGGGCGTCCACCTTCTGATCTGCCCCCGCCTCGCTGANCANGGGGTCTCCGTGTAA; CGCCCCACCCTACCCATGCCAGTGGACATCACTCTGCGCCTCTCTTGCACTCCCAAAAGA; CCCACTTTCGCTGGGAGACTTCCTCCCT;
• Restriction Sites: ECoRI-NOT
• ACCN: NM_001917
• Insert Size: 1590 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001917.3, NP_001908.2
• RefSeq Size: 1576 bp
• RefSeq ORF: 1044 bp
• Locus ID: 1610
• UniProt ID: P14920
• Cytogenetics: 12q24.11
• Domains: DAO
• Protein Families: Druggable Genome
• Protein Pathways: Arginine and proline metabolism, D-Arginine and D-ornithine metabolism, Glycine, Metabolic pathways, serine and threonine metabolism
• Summary: This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq, Jul 2008]