LTBR (NM_002342) Human Untagged Clone

SKU SC118684

LTBR (untagged)-Human lymphotoxin beta receptor (TNFR superfamily, member 3) (LTBR)

Product Data

• Type: Human Untagged Clone
• Target Symbol: LTBR
• Synonyms: D12S370; LT-BETA-R; TNF-R-III; TNFCR; TNFR-RP; TNFR2-RP; TNFR3; TNFRSF3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002342 edited; GAATTCGGCACCAGGGAGCCCTGGAGGCCCGGCCTGGCCGCTCCCGGCCCTGGGGTGCAC; ATCGGCCCTGAGTCCCGTCCCAGGCTCTGGGCTCGGGCAGCCGCCGCCACCGCTGCCCAG; GACGTCGGGCCTCCTGCCTTCCTCCCAGGCCCCCACGTTGCTGGCCGCCTGGCCGAGTGG; CCGCCATGCTCCTGCCTTGGGCCACCTCTGCCCCCGGCCTGGCCTGGGGGCCTCTGGTGC; TGGGCCTCTTCGGGCTCCTGGCAGCATCGCAGCCCCAGGCGGTGCCTCCATATGCGTCGG; AGAACCAGACCTGCAGGGACCAGGAAAAGGAATACTATGAGCCCCAGCACCGCATCTGCT; GCTCCCGCTGCCCGCCAGGCACCTATGTCTCAGCTAAATGTAGCCGCATCCGGGACACAG; TTTGTGCCACATGTGCCGAGAATTCCTACAACGAGCACTGGAACTACCTGACCATCTGCC; AGCTGTGCCGCCCCTGTGACCCAGTGATGGGCCTCGAGGAGATTGCCCCCTGCACAAGCA; AACGGAAGACCCAGTGCCGCTGCCAGCCGGGAATGTTCTGTGCTGCCTGGGCCCTCGAGT; GTACACACTGCGAGCTACTTTCTGACTGCCCGCCTGGCACTGAAGCCGAGCTCAAAGATG; AAGTTGGGAAGGGTAACAACCACTGCGTCCCCTGCAAGGCAGGGCACTTCCAGAATACCT; CCTCCCCCAGCGCCCGCTGCCAGCCCCACACCAGGTGTGAGAACCAAGGTCTGGTGGAGG; CAGCTCCAGGCACTGCCCAGTCCGACACAACCTGCAAAAATCCATTAGAGCCACTGCCCC; CAGAGATGTCAGGAACCATGCTGATGCTGGCCGTTCTGCTGCCACTGGCCTTCTTTCTGC; TCCTTGCCACCGTCTTCTCCTGCATCTGGAAGAGCCACCCTTCTCTCTGCAGGAAACTGG; GATCGCTGCTCAAGAGGCGTCCGCAGGGAGAGGGACCCAATCCTGTAGCTGGAAGCTGGG; AGCCTCCGAAGGCCCATCCATACTTCCCTGACTTGGTACAGCCACTGCTACCCATTTCTG; GAGATGTTTCCCCAGTATCCACTGGGCTCCCCGCAGCCCCAGTTTTGGAGGCAGGGGTGC; CGCAACAGCAGAGTCCTCTGGACCTGACCAGGGAGCCGCAGTTGGAACCCGGGGAGCAGA; GCCAGGTGGCCCACGGTACCAATGGCATTCATGTCACCGGCGGGTCTATGACTATCACTG; GCAACATCTACATCTACAATGGACCAGTACTGGGGGGACCACCGGGTCCTGGAGACCTCC; CAGCTACCCCCGAACCTCCATACCCCATTCCCGAAGAGGGGGACCCTGGCCCTCCCGGGC; TCTCTACACCCCACCAGGAAGATGGCAAGGCTTGGCACCTAGCGGAGACAGAGCACTGTG; GTGCCACACCCTCTAACAGGGGCCCAAGGAACCAATTTATCACCCATGACTGACGGAGTC; TGAGAAAAGGCAGAAGAAGGGGGGCACAAGGGCACCTTCTCCCTTGAGGCTGCCCTGCCC; ACGTGGGATTCACAGGGGCCTGAGTAGGGCCCGGGGAAGCAGAGCCCTAAGGGATTAAGG; CTCAGACACCTCTGAGAGCAGGTGGGCACTGGCTGGGTACGGTGCCCTCCACAGGACTCT; CCCTACTGCCTGAGCAAACCTGAGGCCTCCCGGCAGACCCACCCACCCCCTGGGGCTGCT; CAGCCTCAGGCACGGACAGGGCACATGATACCAACTGCTGCCCACTACGGCACGCCGCAC; CGGAGCACGGCACCGAGGGAGCCGCCACACGGTCACCTGCAAGGACGTCACGGGCCCCTC; TAAAGGATTCGTGGTGCTCATCCCCAAGCTTCAGAGACCCTTTGGGGTTCCACACTTCAC; GTGGACTGAGGTAGACCCTGCATGAAGATGAAATTATAGGGAGGACGCTCCTTCCCTCCC; CTCCTAGAGGAGAGGAAAGGGAGTCATTAACAACTAGGGGGTTGGGTAGGATTCCTAGGT; ATGGGGAAGAGTTTTGGAAGGGGAGGAAAATGGCAAGTGTATTTATATTGTAACCACATG; CAAATAAAAAGAATGGGACCTAGAAAAAAAAAAAAAAAAAACTCGAC;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002342 unedited; NGGTCGCCATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACCAGGAGCCCTGG; AGGCCCGGCCTGGCCGCTCCCGGCCCTGGGGTGCACATCGGCCCTGAGTCCCGTCCCAGG; CTCTGGGCTCGGGCAGCCGCCGCCACCGCTGCCCAGGACGTCGGGCCTCCTGCCTTCCTC; CCAGGCCCCCACGTTGCTGGCCGCCTGGCCGAGTGGCCGCCATGCTCCTGCCTTGGGCCA; CCTCTGCCCCCGGCCTGGCCTGGGGGCCTCTGGTGCTGGGCCTCTTCGGGCTCCTGGCAG; CATCGCAGCCCCAGGCGGTGCCTCCATATGCGTCGGAGAACCAGACCTGCAGGGACCAGG; AAAAGGAATACTATGAGCCCCAGCACCGCATCTGCTGCTCCCGCTGCCCGCCAGGCACCT; ATGTCTCAGCTAAATGTAGCCGCATCCGGGACACAGTTTGTGCCACATGTGCCGAGAATT; CCTACAACGAGCACTGGAACTACCTGACCATCTGCCAGCTGTGCCGCCCCTGTGACCCAG; TGATGGGCCTCGAGGAGATTGCCCCCTGCACAAGCAAACGGAAGACCCAGTGCCGCTGCC; AGCCGGGAATGTTCTGTGCTGCCTGGGCCCTCGAGTGTACACACTGCGAGCTACTTTCTG; ACTGCCCGCCTGGCACTGAAGCCGAGCTCAAAGATGAAGTTGGGAAGGGTAACAACCACT; GCGTCCCCTGCAGGCAGGGCACTTNCAGAATACCTNCTNCCCCAGCGCCCGCTGCCAGCC; CCACACCAGGTGTGAGAACCAAGGTCTGGTGGGAGCAGCTNNCAGCACTGGCCAGTCCGA; CACACCTGCAAAATCCATTANAGCACTGCCCCCAGAGAGTCAGGACCATGCTGATGCTGG; NCCGTCTGCTGCACTGGCCCTCTTCTGCTCTTTGCACGTCTCTC;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002342 unedited; CGAGATCTTTTTNNTTTTTTTTTTTNTCTAGGGTCCCATTCTTTTTATTTGCATGTGGTT; ACAATATAAATACACTTGCCATTTTCCTCCCCTTCCAAAACTCTTCCCCATACCTAGGAA; TCCTACCCAACCCCCTAGTTGTTAATGACTCCCTTTCCTCTCCTCTAGGAGGGGAGGGAA; GGAGCGTCCTCCCTATAATTTCATCTTCATGCAGGGTCTACCTCAGTCCACGTGAAGTGT; GGAACCCCAAAGGTCTCTGAAGCTTGGGGATGAGCACCACGAATCCTTTAGAGGGGCCCG; TGACGTCCTTGCAGGTGACCGTGTGGCGGCTCCCTCGGTGCCGTGCTCCGGTGCGGCGTG; CCGTATTGGGCAGCAGTTGGTATCATGTGCCCTGTCCGTGCCTGAGGCTGAGCAGCCCCA; GGGGGTGGGTGGGTCTGCCGGGAGGCCTCAGGTTTGCTCAGGCAGTAGGGAGAGTCCTGT; GGAGGGCACCGTACCCAGCCAGTGCCCACCTGCTCTCAGAGGTGTCTGAGCCTTAATCCC; TTAGGGCTCTGCTTCCCCGGGCCCTACTCAGGCCCCTGTGAATCCCACGTGGGCAGGGCA; GCCTCAAGGGAGAAGGTGCCCTTGTGCCCCCCTTCTTCTGCCTTTTCTCAGACTCCGTCA; GTCATGGGTGATAAATTGGTTCCTTGGGCCCCTGTTAGAGGGTGTGGCACCACAGTGCTC; TGTCTCCGCTAGGTGCCAAGCCTTGCCATCTTCCTGGTGGGGGGTANAAGACCCCGGNAG; GCCAGGGTCCCCCTCTTCGGAATGGGGTATGGGAGTTCGGGGGTACTTGGGGAGGTCTCA; GGACC;
• Restriction Sites: NotI-NotI
• ACCN: NM_002342
• Insert Size: 2250 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_002342.1, NP_002333.1
• RefSeq Size: 2136 bp
• RefSeq ORF: 1308 bp
• Locus ID: 4055
• UniProt ID: P36941
• Cytogenetics: 12p13.31
• Domains: TNFR
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction
• Summary: This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012]; Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).