LTBR (NM_002342) Human Untagged Clone

CAT#: SC118684

LTBR (untagged)-Human lymphotoxin beta receptor (TNFR superfamily, member 3) (LTBR)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LTBR
• Synonyms: D12S370; LT-BETA-R; TNF-R-III; TNFCR; TNFR-RP; TNFR2-RP; TNFR3; TNFRSF3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002342 edited
  GAATTCGGCACCAGGGAGCCCTGGAGGCCCGGCCTGGCCGCTCCCGGCCCTGGGGTGCAC
  ATCGGCCCTGAGTCCCGTCCCAGGCTCTGGGCTCGGGCAGCCGCCGCCACCGCTGCCCAG
  GACGTCGGGCCTCCTGCCTTCCTCCCAGGCCCCCACGTTGCTGGCCGCCTGGCCGAGTGG
  CCGCCATGCTCCTGCCTTGGGCCACCTCTGCCCCCGGCCTGGCCTGGGGGCCTCTGGTGC
  TGGGCCTCTTCGGGCTCCTGGCAGCATCGCAGCCCCAGGCGGTGCCTCCATATGCGTCGG
  AGAACCAGACCTGCAGGGACCAGGAAAAGGAATACTATGAGCCCCAGCACCGCATCTGCT
  GCTCCCGCTGCCCGCCAGGCACCTATGTCTCAGCTAAATGTAGCCGCATCCGGGACACAG
  TTTGTGCCACATGTGCCGAGAATTCCTACAACGAGCACTGGAACTACCTGACCATCTGCC
  AGCTGTGCCGCCCCTGTGACCCAGTGATGGGCCTCGAGGAGATTGCCCCCTGCACAAGCA
  AACGGAAGACCCAGTGCCGCTGCCAGCCGGGAATGTTCTGTGCTGCCTGGGCCCTCGAGT
  GTACACACTGCGAGCTACTTTCTGACTGCCCGCCTGGCACTGAAGCCGAGCTCAAAGATG
  AAGTTGGGAAGGGTAACAACCACTGCGTCCCCTGCAAGGCAGGGCACTTCCAGAATACCT
  CCTCCCCCAGCGCCCGCTGCCAGCCCCACACCAGGTGTGAGAACCAAGGTCTGGTGGAGG
  CAGCTCCAGGCACTGCCCAGTCCGACACAACCTGCAAAAATCCATTAGAGCCACTGCCCC
  CAGAGATGTCAGGAACCATGCTGATGCTGGCCGTTCTGCTGCCACTGGCCTTCTTTCTGC
  TCCTTGCCACCGTCTTCTCCTGCATCTGGAAGAGCCACCCTTCTCTCTGCAGGAAACTGG
  GATCGCTGCTCAAGAGGCGTCCGCAGGGAGAGGGACCCAATCCTGTAGCTGGAAGCTGGG
  AGCCTCCGAAGGCCCATCCATACTTCCCTGACTTGGTACAGCCACTGCTACCCATTTCTG
  GAGATGTTTCCCCAGTATCCACTGGGCTCCCCGCAGCCCCAGTTTTGGAGGCAGGGGTGC
  CGCAACAGCAGAGTCCTCTGGACCTGACCAGGGAGCCGCAGTTGGAACCCGGGGAGCAGA
  GCCAGGTGGCCCACGGTACCAATGGCATTCATGTCACCGGCGGGTCTATGACTATCACTG
  GCAACATCTACATCTACAATGGACCAGTACTGGGGGGACCACCGGGTCCTGGAGACCTCC
  CAGCTACCCCCGAACCTCCATACCCCATTCCCGAAGAGGGGGACCCTGGCCCTCCCGGGC
  TCTCTACACCCCACCAGGAAGATGGCAAGGCTTGGCACCTAGCGGAGACAGAGCACTGTG
  GTGCCACACCCTCTAACAGGGGCCCAAGGAACCAATTTATCACCCATGACTGACGGAGTC
  TGAGAAAAGGCAGAAGAAGGGGGGCACAAGGGCACCTTCTCCCTTGAGGCTGCCCTGCCC
  ACGTGGGATTCACAGGGGCCTGAGTAGGGCCCGGGGAAGCAGAGCCCTAAGGGATTAAGG
  CTCAGACACCTCTGAGAGCAGGTGGGCACTGGCTGGGTACGGTGCCCTCCACAGGACTCT
  CCCTACTGCCTGAGCAAACCTGAGGCCTCCCGGCAGACCCACCCACCCCCTGGGGCTGCT
  CAGCCTCAGGCACGGACAGGGCACATGATACCAACTGCTGCCCACTACGGCACGCCGCAC
  CGGAGCACGGCACCGAGGGAGCCGCCACACGGTCACCTGCAAGGACGTCACGGGCCCCTC
  TAAAGGATTCGTGGTGCTCATCCCCAAGCTTCAGAGACCCTTTGGGGTTCCACACTTCAC
  GTGGACTGAGGTAGACCCTGCATGAAGATGAAATTATAGGGAGGACGCTCCTTCCCTCCC
  CTCCTAGAGGAGAGGAAAGGGAGTCATTAACAACTAGGGGGTTGGGTAGGATTCCTAGGT
  ATGGGGAAGAGTTTTGGAAGGGGAGGAAAATGGCAAGTGTATTTATATTGTAACCACATG
  CAAATAAAAAGAATGGGACCTAGAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002342 unedited
  NGGTCGCCATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACCAGGAGCCCTGG
  AGGCCCGGCCTGGCCGCTCCCGGCCCTGGGGTGCACATCGGCCCTGAGTCCCGTCCCAGG
  CTCTGGGCTCGGGCAGCCGCCGCCACCGCTGCCCAGGACGTCGGGCCTCCTGCCTTCCTC
  CCAGGCCCCCACGTTGCTGGCCGCCTGGCCGAGTGGCCGCCATGCTCCTGCCTTGGGCCA
  CCTCTGCCCCCGGCCTGGCCTGGGGGCCTCTGGTGCTGGGCCTCTTCGGGCTCCTGGCAG
  CATCGCAGCCCCAGGCGGTGCCTCCATATGCGTCGGAGAACCAGACCTGCAGGGACCAGG
  AAAAGGAATACTATGAGCCCCAGCACCGCATCTGCTGCTCCCGCTGCCCGCCAGGCACCT
  ATGTCTCAGCTAAATGTAGCCGCATCCGGGACACAGTTTGTGCCACATGTGCCGAGAATT
  CCTACAACGAGCACTGGAACTACCTGACCATCTGCCAGCTGTGCCGCCCCTGTGACCCAG
  TGATGGGCCTCGAGGAGATTGCCCCCTGCACAAGCAAACGGAAGACCCAGTGCCGCTGCC
  AGCCGGGAATGTTCTGTGCTGCCTGGGCCCTCGAGTGTACACACTGCGAGCTACTTTCTG
  ACTGCCCGCCTGGCACTGAAGCCGAGCTCAAAGATGAAGTTGGGAAGGGTAACAACCACT
  GCGTCCCCTGCAGGCAGGGCACTTNCAGAATACCTNCTNCCCCAGCGCCCGCTGCCAGCC
  CCACACCAGGTGTGAGAACCAAGGTCTGGTGGGAGCAGCTNNCAGCACTGGCCAGTCCGA
  CACACCTGCAAAATCCATTANAGCACTGCCCCCAGAGAGTCAGGACCATGCTGATGCTGG
  NCCGTCTGCTGCACTGGCCCTCTTCTGCTCTTTGCACGTCTCTC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002342 unedited
  CGAGATCTTTTTNNTTTTTTTTTTTNTCTAGGGTCCCATTCTTTTTATTTGCATGTGGTT
  ACAATATAAATACACTTGCCATTTTCCTCCCCTTCCAAAACTCTTCCCCATACCTAGGAA
  TCCTACCCAACCCCCTAGTTGTTAATGACTCCCTTTCCTCTCCTCTAGGAGGGGAGGGAA
  GGAGCGTCCTCCCTATAATTTCATCTTCATGCAGGGTCTACCTCAGTCCACGTGAAGTGT
  GGAACCCCAAAGGTCTCTGAAGCTTGGGGATGAGCACCACGAATCCTTTAGAGGGGCCCG
  TGACGTCCTTGCAGGTGACCGTGTGGCGGCTCCCTCGGTGCCGTGCTCCGGTGCGGCGTG
  CCGTATTGGGCAGCAGTTGGTATCATGTGCCCTGTCCGTGCCTGAGGCTGAGCAGCCCCA
  GGGGGTGGGTGGGTCTGCCGGGAGGCCTCAGGTTTGCTCAGGCAGTAGGGAGAGTCCTGT
  GGAGGGCACCGTACCCAGCCAGTGCCCACCTGCTCTCAGAGGTGTCTGAGCCTTAATCCC
  TTAGGGCTCTGCTTCCCCGGGCCCTACTCAGGCCCCTGTGAATCCCACGTGGGCAGGGCA
  GCCTCAAGGGAGAAGGTGCCCTTGTGCCCCCCTTCTTCTGCCTTTTCTCAGACTCCGTCA
  GTCATGGGTGATAAATTGGTTCCTTGGGCCCCTGTTAGAGGGTGTGGCACCACAGTGCTC
  TGTCTCCGCTAGGTGCCAAGCCTTGCCATCTTCCTGGTGGGGGGTANAAGACCCCGGNAG
  GCCAGGGTCCCCCTCTTCGGAATGGGGTATGGGAGTTCGGGGGTACTTGGGGAGGTCTCA
  GGACC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002342
• Insert Size: 2250 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002342.1, NP_002333.1
• RefSeq Size: 2136 bp
• RefSeq ORF: 1308 bp
• Locus ID: 4055
• UniProt ID: P36941
• Cytogenetics: 12p13.31
• Domains: TNFR
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction
• Gene Summary: This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).