PIGR (NM_002644) Human Untagged Clone

CAT#: SC118484

PIGR (untagged)-Human polymeric immunoglobulin receptor (PIGR)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PIGR
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002644 edited
  GAATTCGGCACGAGCAACTGGCCAGCAGGCTGTGTCCCTGAAGTCAGATCAACGGGAGAG
  AAGGAAGTGGCTAAAACATTGCACAGGAGAAGTCGGCCTGAGTGGTGCGGCGCTCGGGAC
  CCACCAGCAATGCTGCTCTTCGTGCTCACCTGCCTGCTGGCGGTCTTCCCAGCCATCTCC
  ACGAAGAGTCCCATATTTGGTCCCGAGGAGGTGAATAGTGTGGAAGGTAACTCAGTGTCC
  ATCACGTGCTACTACCCACCCACCTCTGTCAACCGGCACACCCGGAAGTACTGGTGCCGG
  CAGGGAGCTAGAGGTGGCTGCATAACCCTCATCTCCTCGGAGGGCTACGTCTCCAGCAAA
  TATGCAGGCAGGGCTAACCTCACCAACTTCCCGGAGAACGGCACATTTGTGGTGAACATT
  GCCCAGCTGAGCCAGGATGACTCCGGGCGCTACAAGTGTGGCCTGGGCATCAATAGCCGA
  GGCCTGTCCTTTGATGTCAGCCTGGAGGTCAGCCAGGGTCCTGGGCTCCTAAATGACACT
  AAAGTCTACACAGTGGACCTGGGCAGAACGGTGACCATCAACTGCCCTTTCAAGACTGAG
  AATGCTCAAAAGAGGAAGTCCTTGTACAAGCAGATAGGCCTGTACCCTGTGCTGGTCATC
  GACTCCAGTGGTTATGTAAATCCCAACTATACAGGAAGAATACGCCTTGATATTCAGGGT
  ACTGGCCAGTTACTGTTCAGCGTTGTCATCAACCAACTCAGGCTCAGCGATGCTGGGCAG
  TATCTCTGCCAGGCTGGGGATGATTCCAATAGTAATAAGAAGAATGCTGACCTCCAAGTG
  CTAAAGCCCGAGCCCGAGCTGGTTTATGAAGACCTGAGGGGCTCAGTGACCTTCCACTGT
  GCCCTGGGCCCTGAGGTGGCAAACGTGGCCAAATTTCTGTGCCGACAGAGCAGTGGGGAA
  AACTGTGACGTGGTCGTCAACACCCTGGGGAAGAGGGCCCCAGCCTTTGAGGGCAGGATC
  CTGCTCAACCCCCAGGACAAGGATGGCTCATTCAGTGTGGTGATCACAGGCCTGAGGAAG
  GAGGATGCAGGGCGCTACCTGTGTGGAGCCCATTCGGATGGTCAGCTGCAGGAAGGCTCG
  CCTATCCAGGCCTGGCAACTCTTCGTCAATGAGGAGTCCACGATTCCCCGCAGCCCCACT
  GTGGTGAAGGGGGTGGCAGGAGGCTCTGTGGCCGTGCTCTGCCCCTACAACCGTAAGGAA
  AGCAAAAGCATCAAGTACTGGTGTCTCTGGGAAGGGGCCCAGAATGGCCGCTGCCCCCTG
  CTGGTGGACAGCGAGGGGTGGGTTAAGGCCCAGTACGAGGGCCGCCTCTCCCTGCTGGAG
  GAGCCAGGCAACGGCACCTTCACTGTCATCCTCAACCAGCTCACCAGCCGGGACGCCGGC
  TTCTACTGGTGTCTGACCAACGGCGATACTCTCTGGAGGACCACCGTGGAGATCAAGATT
  ATCGAAGGAGAACCAAACCTCAAGGTACCAGGGAATGTCACGGCTGTGCTGGGAGAGACT
  CTCAAGGTCCCCTGTCACTTTCCATGCAAATTCTCCTCGTACGAGAAATACTGGTGCAAG
  TGGAATAACACGGGCTGCCAGGCCCTGCCCAGCCAAGACGAAGGCCCCAGCAAGGCCTTC
  GTGAACTGTGACGAGAACAGCCGGCTTGTCTCCCTGACCCTGAACCTGGTGACCAGGGCT
  GATGAGGGCTGGTACTGGTGTGGAGTGAAGCAGGGCCACTTCTATGGAGAGACTGCAGCC
  GTCTATGTGGCAGTTGAAGAGAGGAAGGCAGCGGGGTCCCGCGATGTCAGCCTAGCGAAG
  GCAGACGCTGCTCCTGATGAGAAGGTGCTAGACTCTGGTTTTCGGGAGATTGAGAACAAA
  GCCATTCAGGATCCCAGGCTTTTTGCAGAGGAAAAGGCGGTGGCAGATACAAGAGATCAA
  GCCGATGGGAGCAGAGCATCTGTGGATTCCGGCAGCTCTGAGGAACAAGGTGGAAGCTCC
  AGAGCGCTGGTCTCCACCCTGGTGCCCCTGGGCCTGGTGCTGGCAGTGGGAGCCGTGGCT
  GTGGGGGTGGCCAGAGCCCGGCACAGGAAGAACGTCGACCGAGTTTCAATCAGAAGCTAC
  AGGACAGACATTAGCATGTCAGACTTCGAGAACTCCAGGGAATTTGGAGCCAATGACAAC
  ATGGGAGCCTCTTCGATCACTCAGGAGACATCCCTCGGAGGAAAAGAAGAGTTTGTTGCC
  ACCACTGAGAGCACCACAGAGACCAAAGAACCCAAGAAGGCAAAAAGGTCATCCAAGGAG
  GAAGCCGAGATGGCCTACAAAGACTTCCTGCTCCAGTCCAGCACCGTGGCCGCCGAGGCC
  CAGGACGGCCCCCAGGAAGCCTAGACGGTGTCGCCGCCTGCTCCCTGCACCCATGACAAT
  CACCTTCAGAATCATGTCGATCCTGGGGCCCTCAGCTCCTGGGGACCCCACTCCCTGCTC
  TAACACCTGCCTAGGTTTTTCCTACTGTCCTCAGAGGCGTGCTGGTCCCCTCCTCAGTGA
  CATCAAAGCCTGGCCTAATTGTTCCTATTGGGGATGAGGGTGGCATGAGGAGGTCCCACT
  TGCAACTTCTTTCTGTTGAGAGAACCTCAGGTACGGAGAAGAATAGAGGTCCTCATGGGT
  CCCTTGAAGGAAGAGGGACCAGGGTGGGAGAGCTGATTGCAGAAAGGAGAGACGTGCAGC
  GCCCCTCTGCACCCTTATCATGGGATGTCAACAGAATTTTTCCCTCCACTCCATCCCTCC
  CTCCCGTCCTTCCCCTCTTCTTCTTTCCTTCCATCAAAAGATGTATTTGAATTCATACTA
  GAATTCAGGTGCTTTGCTAGATGCTGTGACAGGTATGCCACCAACACTGCTCACAGCCTT
  TCTGAGGACACCAGTGAAAGAAGCCACAGCTCTTCTTGGCGTATTTATACTCACTGAGTC
  TTAACTTTTCACCXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002644 unedited
  GAATTTGTAATACGAACTCACTATAGGGCGGCCGCGAATTCGCACGAGCAACTGGCCAGC
  AGGCTGTGTCCCTGAAGTCAGATCAACGGGAGAGAAGGAAGTGGCTAAAACATTGCACAG
  GAGAAGTCGGCCTGAGTGGTGCGGCGCTCGGGACCCACCAGCAATGCTGCTCTTCGTGCT
  CACCTGCCTGCTGGCGGTCTTCCCAGCCATCTCCACGAAGAGTCCCATATTTGGTCCCGA
  GGAGGTGAATAGTGTGGAAGGTAACTCAGTGTCCATCACGTGCTACTACCCACCCACCTC
  TGTCAACCGGCACACCCGGAAGTACTGGTGCCGGCAGGGAGCTAGAGGTGGCTGCATAAC
  CCTCATCTCCTCGGAGGGCTACGTCTCCAGCAAATATGCAGGCAGGGCTAACCTCACCAA
  CTTCCCGGAGAACGGCACATTTGTGGTGAACATTGCCCAGCTGAGCCAGGATGACTCCGG
  GCGCTACAAGTGTGGCCTGGGCATCAATAGCCGAGGCCTGTCCTTTGATGTCAGCCTGGA
  GGTCAGCCAGGGTCCTGNGCTCCTAAATGACACTAAAGTCTACACAGTGGACCTGGGCAG
  AACGGTGACCATCAACTGCCCTTTCAAGACTGAGAATGCTCAAAAGAGGAAGTCCTTGTA
  CAAGCAGATAGGCCTGTACCCTGTGCTGGTCATCGACTCCAGTGGTTATGTAAATCCCAA
  CTATACAGGAAAGATACGCNCTGATATTCAGGNTACTGGCCAGTTACTGTTCAGCGTTGT
  CATCACCAAACTCAGCTCAGCGATGCTGGGCAGTATCTCTGCCCAGCTGGGGATGATNCC
  AANTAGTATAGAAGATGCTGACCTNCAAGTGCTAAAGCCCGAGCCGAGCTGGNTTATGAA
  GACCTGAGGGCTCAGTGACCTTCACTGTGCCCCTGGCCCCTGAGTGCAAACGTGGCCAAT
  TTCTGTGCCGACGAGCANTGGGGAAAACTGTGACATNGTCGTAACACC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002644 unedited
  AAAAAGGTCNCGGGCGTTCTGCTCAGTATTACAAGTACGGATCTNCTGAACTCGTGTGAC
  CTAGAGCCATGCTGGCGAGTCTGGTTGAAAACAGCAGTGATAGGATAAAAAAAATAAATT
  GTACCTGTCTGGAGAGCAGCCCCTTTATGGGACCATAAAACACTAAATTGTATCCCTTAA
  ACTCGGAACTGTGCCAACATAATGTGTAGAGAAGGCCCGGCCATTCTTTTATATGGACAC
  CATGTGAGTGACAGAAAGAGGCAGACTAGAAAAGATCTCGCTGCTTAACATTTTCTATTC
  TCACTACTTCTGCTTATTATAAAACCGCGCCTATCAACAAATGGGCAAGGGCTCTCAGCA
  CATAGATCCCTGAACAAGGACAGGAGATGCGCAAACTAATAAATCTCACTGAGGGCCTTA
  GAGAAAAACGCTTCCAGACCACGCTCAGTGGCTCATGCCTATCTAATACCAGTACTCTGA
  AAACCTGATGCGGCATATCACTTGATGCCAAAAGTTCGAGACCAGTCTCGTAACATGGCA
  AAACCCTGTCTCTACANNNAANANAAAAAAAAAAAAATTAGCCAGACATGGTGGCCCACA
  TCTGTAGTCCCACCTACTTGAGAGGCTGAGGCATGAGAATACCTTGAACCTGGAAAGCAC
  AAGTTTCAGTGACCCGAGATTGGCTCACTGCATTCCAGGCTGGGTGACACAGGGAGACTT
  TGTCTTCACACAAAGGAAAAGAAAAAAAGAAGCCCGGACCCGGTGGCTCCCGCCCTGTAA
  TCCCAACCCTTTTGTGGAGGCCAACGCAGGCGGGTCCACCAAGGCAGGAGATCGAAACCA
  TTCTGGTTAACCCGGGGCAACCCTGTCTTTTCTAAAAACCAGAAAATTTTCAAGGCTTTC
  TTGCAAGGGCATTAAAAACA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002644
• Insert Size: 4350 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002644.2, NP_002635.2
• RefSeq Size: 4266 bp
• RefSeq ORF: 2295 bp
• Locus ID: 5284
• UniProt ID: P01833
• Cytogenetics: 1q32.1
• Domains: ig, IGv, IG
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Gene Summary: This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.[provided by RefSeq, Sep 2009]