VMAT2 (SLC18A2) (NM_003054) Human Untagged Clone

CAT#: SC118200

SLC18A2 (untagged)-Human solute carrier family 18 (vesicular monoamine), member 2 (SLC18A2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: VMAT2
• Synonyms: PKDYS2; SVAT; SVMT; VAT2; VMAT2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC118200 sequence for NM_003054 edited (data generated by NextGen Sequencing)
  ATGGCCCTGAGCGAGCTGGCGCTGGTCCGCTGGCTGCAGGAGAGCCGCCGCTCGCGGAAG
  CTCATCCTGTTCATCGTGTTCCTGGCGCTGCTGCTGGACAACATGCTGCTCACTGTCGTG
  GTCCCCATCATCCCAAGTTATCTGTACAGCATTAAGCATGAGAAGAATGCTACAGAAATC
  CAGACGGCCAGGCCAGTGCACACTGCCTCCATCTCAGACAGCTTCCAGAGCATCTTCTCC
  TATTATGATAACTCGACTATGGTCACCGGGAATGCTACCAGAGACCTGACACTTCATCAG
  ACCGCCACACAGCACATGGTGACCAACGCGTCCGCTGTTCCTTCCGACTGTCCCAGTGAA
  GACAAAGACCTCCTGAATGAAAACGTGCAAGTTGGTCTGTTGTTTGCCTCGAAAGCCACC
  GTCCAGCTCATCACCAACCCTTTCATAGGACTACTGACCAACAGAATTGGCTATCCAATT
  CCCATATTTGCGGGATTCTGCATCATGTTTGTCTCAACAATTATGTTTGCCTTCTCCAGC
  AGCTATGCCTTCCTGCTGATTGCCAGGTCGCTGCAGGGCATCGGCTCGTCCTGCTCCTCT
  GTGGCTGGGATGGGCATGCTTGCCAGTGTCTACACAGATGATGAAGAGAGAGGCAACGTC
  ATGGGAATCGCCTTGGGAGGCCTGGCCATGGGGGTCTTAGTGGGCCCCCCCTTCGGGAGT
  GTGCTCTATGAGTTTGTGGGGAAGACGGCTCCGTTCCTGGTGCTGGCCGCCCTGGTACTC
  TTGGATGGAGCTATTCAGCTCTTTGTGCTCCAGCCGTCCCGGGTGCAGCCAGAGAGTCAG
  AAGGGGACACCCCTAACCACGCTGCTGAAGGACCCGTACATCCTCATTGCTGCAGGCTCC
  ATCTGCTTTGCAAACATGGGCATCGCCATGCTGGAGCCAGCCCTGCCCATCTGGATGATG
  GAGACCATGTGTTCCCGAAAGTGGCAGCTGGGCGTTGCCTTCTTGCCAGCTAGTATCTCT
  TATCTCATTGGAACCAATATTTTTGGGATACTTGCACACAAAATGGGGAGGTGGCTTTGT
  GCTCTTCTGGGAATGATAATTGTTGGAGTCAGCATTTTATGTATTCCATTTGCAAAAAAC
  ATTTATGGACTCATAGCTCCGAACTTTGGAGTTGGTTTTGCAATTGGAATGGTGGATTCG
  TCAATGATGCCTATCATGGGCTACCTCGTAGACCTGCGGCACGTGTCCGTCTATGGGAGT
  GTGTACGCCATTGCGGATGTGGCATTTTGTATGGGGTATGCTATAGGTCCTTCTGCTGGT
  GGTGCTATTGCAAAGGCAATTGGATTTCCATGGCTCATGACAATTATTGGGATAATTGAT
  ATTCTTTTTGCCCCTCTCTGCTTTTTTCTTCGAAGTCCACCTGCCAAAGAAGAAAAAATG
  GCTATTCTCATGGATCACAACTGCCCTATTAAAACAAAAATGTACACTCAGAATAATATC
  CAGTCATATCCGATAGGTGAAGATGAAGAATCTGAAAGTGACTGA
  
  Clone variation with respect to NM_003054.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003054 unedited
  ACCATTTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGCCCACTGCGGTGC
  GGGCGTTGGCGCGGGCACGGAGGACCCGGGCAGGCATCGCAAGCGACCCCGAGCGGAGCC
  CCGGAGCCATGGCCCTGAGCGAGCTGGCGCTGGTCCGCTGGCTGCAGGAGAGCCGCCGCT
  CGCGGAAGCTCATCCTGTTCATCGTGTTCCTGGCGCTGCTGCTGGACAACATGCTGCTCA
  CTGTCGTGGTCCCCATCATCCCAAGTTATCTGTACAGCATTAAGCATGAGAAGAATGCTA
  CAGAAATCCAGACGGCCAGGCCAGTGCACACTGCCTCCATCTCAGACAGCTTCCAGAGCA
  TCTTCTCCTATTATGATAACTCGACTATGGTCACCGGGAATGCTACCAGAGACCTGACAC
  TTCATCAGACCGCCACACAGCACATGGTGACCAACGCGTCCGCTGTTCCTTCCGACTGTC
  CCAGTGAAGACAAAGACCTCCTGAATGAAAACGTGCAAGTTGGTCTGTTGTTTGCCTCGA
  AAGCCACCGTCCAGCTCATCACCAACCCTTTCATAGGACTACTGACCAACAGAATTGGCT
  ATCCAATTCCCATATTTGCGGGATTCTGCATCATGTTTGTCTCAACAATTATGTTTGCCT
  TCTCCAGCAGCTATGCCTTCCTGCTGATTGCCAGGTCGCTGCAGGGCATCGGCTCGTCCT
  GCTCCTCTGTGGCTGGGATGGGCATGCTTGCCAGTGTCTACACAGATGATGAAGAGAGAG
  GGCACGTCATGGGGATCGNNCTTGGGAGCCTGCCATGGNGGTTCTANTGGCCCCCCCCTT
  CGGNAGTGTGCTCTATGAGTTTTGTGGGGAAAGACGGGCTTCGTCCTGGTGCTGGGCGNC
  CTGGTACCCTGGNATGGAGCATTTCACCTCTTTGTGCTCCACCCGGTCCCGGGTGCAGCC
  AGAAAGTCANAAGGGCCACCCCTTACCACCCTGCTGAAGGAN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003054 unedited
  GCTATTTTCAAGTATACTTGCTAAAATATGGACAGCTACACTTAGCAGTCAAACAGTTGA
  ATATTCATTGCTACCTCATTAAAGTTTTTGTATCTGTATTACCAGGTCCAAACATAAAAA
  CCACCTCTGTTCAAAAAATAAATGTTCAGAGAGCTGTATGTTCTTTGTTCTGGTATGTAC
  ATTTTAAAAAAACACCTCTTTCCAGTCTTGCTAACCAAGAATATTAGTCATATAAAAGAA
  CTTAGAATTTTTTTCCCCAAGTACAAGCTATCTTTTGCTCCAAAACAGTTCTGAAGGCCC
  TATTTATATTCCATCTTATCCCGAGGGACCAACAGCAGGCCTACCTTTTTCAGGTTTCCT
  CGCACCATTACCCATAGCCCCTTATGCCAATATCACCTTGCCCCAATATCTCACTCCTTG
  CCGTCATGGTTCACTCTATCCTTTCCCATTCACCCTACCTTCCCCCATAACTTTTTTACT
  GCTTTCCCCTTCCCTCCCCTTACCCCCGCTTTCCTTCCACCCCTCCTCTTCTTTCCTCCC
  CCCCTTCTTCATTTTTTCCTTCCCTTTTCTTTCTCTCTCCGTTTTCTTCCTTTTCTTTCC
  CTCTTCCCTTCCTTACTCCTTTGACTTTTCCACCTCCCCTTACTATTGTTTTCTCTCCCC
  TTTATTCCCCATCTTCCCCTTCCCTCTCCCTCCCTTATCCCCACCACTTAATTCATTATC
  TTTTTATATTTTTTTCTCCTATACTCCTTCCCCCTTCTCTTTACTACTTTTCTCCTCTTC
  CTTTTCTCTCTTTTACCCTTCATATCTCCCGCGCTACCCCCTTTCTTTCTTATCGCTCNC
  TACTTCCATATCACTCTCCTCCTCCTCCTCCTCTTCTCGTCTCTCTCTTCTTGCTTTCGT
  CTTCGCTCCCCCTCCCCCCGCTCCACTTCTCTCTCCATCTCGCCTTTTGTCTGCTCACTA
  CATTTCTAACCCTCATTCCTCCGTCTTTCGATCTATCCATTNTTATATCCTCGCGCTCAC
  TCACTACTTCTCTTCTCATTATCTCTTACCTTACTAGTTCTTATCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003054
• Insert Size: 3890 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003054.2, NP_003045.2
• RefSeq Size: 1898 bp
• RefSeq ORF: 1545 bp
• Locus ID: 6571
• UniProt ID: Q05940
• Cytogenetics: 10q25.3
• Protein Families: Transmembrane
• Protein Pathways: Parkinson's disease
• Gene Summary: This gene encodes an transmembrane protein that functions as an ATP-dependent transporter of monoamines, such as dopamine, norepinephrine, serotonin, and histamine. This protein transports amine neurotransmitters into synaptic vesicles. Polymorphisms in this gene may be associated with schizophrenia, bipolar disorder, and other neurological/psychiatric ailments. [provided by RefSeq, Jun 2018]