UVRAG (NM_003369) Human Untagged Clone

CAT#: SC117982

UVRAG (untagged)-Human UV radiation resistance associated gene (UVRAG)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UVRAG
• Synonyms: DHTX; p63; VPS38
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117982 sequence for NM_003369 edited (data generated by NextGen Sequencing)
  ATGAGCGCCTCCGCGTCGGTCGGGGGCCCCGTCCCCCAGCCACCCCCGGGCCCGGCCGCT
  GCTCTGCCTCCCGGTTCTGCCGCGCGGGCCCTGCATGTGGAGCTGCCGTCTCAGCAGCGG
  CGTCTTCGACATCTTCGGAACATTGCTGCCCGGAACATTGTTAATAGAAATGGCCATCAG
  CTCCTTGATACCTACTTTACACTTCACTTGTGTAGTACTGAAAAGATATATAAAGAATTT
  TATAGAAGTGAAGTGATTAAGAATTCCTTGAATCCCACGTGGCGAAGTCTCGATTTTGGA
  ATTATGCCAGACCGTCTTGATACATCTGTGTCTTGTTTCGTGGTGAAGATATGGGGTGGA
  AAGGAGAACATCTACCAGCTGTTGATTGAATGGAAAGTCTGTTTGGATGGGCTGAAATAC
  TTGGGTCAGCAGATTCATGCCCGAAACCAAAATGAAATAATTTTTGGGCTGAATGATGGA
  TACTATGGTGCTCCATTTGAACATAAGGGTTATTCAAATGCTCAGAAGACTATTCTTCTG
  CAGGTGGATCAGAACTGTGTTCGCAATTCTTACGATGTCTTCTCTTTGCTACGGCTTCAT
  AGAGCCCAGTGTGCAATTAAACAGACTCAGGTAACTGTTCAGAAAATTGGAAAGGAAATT
  GAAGAAAAACTAAGACTCACATCTACAAGCAATGAACTGAAAAAAAAAAGTGAATGCCTG
  CAGTTAAAAATTTTGGTGCTTCAGAATGAACTGGAACGGCAGAAGAAAGCTTTGGGACGG
  GAGGTGGCATTACTGCATAAGCAACAAATTGCATTACAAGACAAAGGAAGTGCATTTTCA
  GCTGAGCACCTCAAACTTCAACTCCAGAAGGAATCCCTAAATGAGCTGAGGAAGGAGTGC
  ACTGCAAAAAGAGAACTCTTCTTGAAGACTAATGCTCAGTTGACAATTCGTTGCAGGCAG
  TTACTCTCTGAGCTTTCCTACATTTACCCTATTGATTTGAATGAACATAAGGATTACTTT
  GTATGCGGTGTCAAGTTGCCTAATTCTGAGGACTTCCAAGCAAAAGATGATGGAAGCATT
  GCTGTTGCCCTTGGTTATACTGCACATCTGGTCTCCATGATTTCCTTTTTCCTACAAGTG
  CCCCTCAGATATCCTATAATTCATAAGGGGTCTAGATCAACAATCAAAGACAATATCAAT
  GACAAACTGACGGAAAAGGAGAGAGAGTTTCCACTGTATCCAAAAGGAGGGGAGAAGTTG
  CAGTTTGATTATGGTGTCTATCTTCTGAACAAAAATATAGCACAGCTAAGATATCAACAT
  GGACTAGGGACTCCAGACTTGCGGCAAACCCTTCCCAACCTGAAAAACTTCATGGAGCAT
  GGACTAATGGTCAGGTGTGACAGACATCACACCTCCAGTGCAATCCCTGTTCCTAAGAGA
  CAAAGCTCCATATTTGGGGGTGCAGATGTAGGCTTCTCTGGGGGGATCCCTTCACCAGAC
  AAAGGACATCGAAAACGGGCCAGCTCTGAGAATGAGAGACTTCAGTACAAAACCCCTCCT
  CCCAGTTACAACTCAGCATTAGCCCAGCCTGTGACCACCGTCCCCTCCATGGGAGAGACC
  GAGAGAAAGATAACATCTCTATCCTCCTCCTTGGATACCTCCTTGGACTTCTCCAAAGAA
  AACAAGAAAAAAGGAGAGGATCTAGTTGGCAGCTTAAACGGAGGCCACGCGAATGTGCAC
  CCTAGCCAAGAACAAGGAGAAGCCCTCTCCGGGCACCGGGCCACAGTCAATGGCACTCTC
  CTACCCAGCGAGCAGGCCGGGTCCGCCAGTGTCCAGCTTCCAGGCGAGTTCCACCCAGTC
  TCAGAAGCTGAGCTCTGCTGTACTGTGGAGCAAGCAGAAGAAATCATCGGGCTGGAAGCC
  ACAGGTTTCGCCTCAGGTGATCAGCTAGAAGCATTTAACTGCATCCCAGTGGACAGTGCT
  GTGGCAGTAGAGTGTGACGAACAAGTTCTGGGAGAATTTGAAGAGTTCTCCCGAAGGATC
  TATGCACTGAATGAAAACGTATCCAGCTTCCGCCGGCCGCGCAGGAGTTCCGATAAGTGA
  
  Clone variation with respect to NM_003369.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003369 unedited
  ATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGTGCCCGCCCCGCCGCTTGG
  CGGCCCCTGGATCGAGATGAGCGCCTCCGCGTCGGTCGGGGGCCCCGTCCCCCAGCCACC
  CCCGGGCCCGGCCGCTGCTCTGCCTCCCGGTTCTGCCGCGCGGGCCCTGCATGTGGAGCT
  GCCGTCTCAGCAGCGGCGTCTTCGACATCTTCGGAACATTGCTGCCCGGAACATTGTTAA
  TAGAAATGGCCATCAGCTCCTTGATACCTACTTTACACTTCACTTGTGTAGTACTGAAAA
  GATATATAAAGAATTTTATAGAAGTGAAGTGATTAAGAATTCCTTGAATCCCACGTGGCG
  AAGTCTCGATTTTGGAATTATGCCAGACCGTCTTGATACATCTGTGTCTTGTTTCGTGGT
  GAAGATATGGGGTGGAAAGGAGAACATCTACCAGCTGTTGATTGAATGGAAAGTCTGTTT
  GGATGGGCTGAAATACTTGGGTCAGCAGATTCATGCCCGAAACCAAAATGAAATAATTTT
  TGGGCTGAATGATGGATACTATGGTGCTCCATTTGAACATAGGGTTATTCANATGCTCAG
  AAGACTATTCTTCTGCAGGTGGATCAGAACTGTNGTCGCAATTCTTACGATGTCTTCTCT
  TTGCTACGGCTTCATAGAGCCCAGTGTGCAATAAACAGACTCANNGTACTGNTCANAANA
  TNGNAAGGNAANNNTGAGANNNACTAGACTCACATCTACCNAGCATGAACTGAAAAAAAA
  AGTGAATGCTGCAGTAAAAATNTTTGTGCTTCANAATGAACTGGACGCAAANAAAGCTTG
  GNACGGGNAGTGGCATACTGCCATAGCACAATGCCTACAGACAAGGAGTGCATTTAGCTG
  ACACCTAACTCACTCAGAAGATCCCTATGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003369 unedited
  GCACGCAATCTAAAGTCGAGTTTTTTTTTTTTTTTTTTTTTGAAGTAAACTCAATTTTTA
  TTCTTCTATATAATACATGGATATATGGATAAATTTTCCTTTAAAGAGTTTGCAACCCTG
  AGGCAATGTCCTTGGGTACGTAACGTATAAAGCAACAGCAAATGAAATCTGAATGCGGGA
  ATGACAACTGGACTTCGAAACATAATTTAATATTCATGAAATTGCACACATACCAATAGT
  ATTCTATGTCTCGTCTAGCCTCTTAATCCAACTATCTCAACTGCCTTGCAGTTTGCCTAC
  CAGACACCCCAACTCTCTACATACATTCTGTCATGTAAATGCTGACCTTCTGACTGAAAT
  TTAATAAATTAACATGGGATTTACATCAAGGGATTTTTGTCTGGTGAGTGCATTGCCAGA
  AAGCATGCCTAGTTCCTGACCACAGCATCTGCCCACATAAAAACTTTGGCCCCCACAGGG
  GATGAGATGGCATCTGACTGCAGTAACCTCGAGGTCCTTGAAGGTCCCTTGGGATCCACC
  AGGAGCAAGTTTTTCATCTAATCTGAAGGCCGCATTAAGGGTATGGCAAAAGAGGGGAAG
  GCCATGGCTGGTTATAAGAGATGGAACGTCACAGCTCCTGGGTTACAGAACCAGTGAATC
  TGATGTCCTGTTTTCAGGACGCATGGCCCATCCACGGAAATATGGGGCGACAGTATGGTT
  ATAAGTGGACTGTGGTACCCGGGGCCAGAAAGGGAAGTTAGCCTAATGTAAGAGACCCTT
  TGCTGCTTCTTATTACCTAAAAGGCCCAAACTTTAGTCTGGCGGAACTTTTTGATTTTCC
  TTTCCAAATTTTTACCTGGGAGGCAAGCCTTAAAACAGGGGGGCACTAATATTTATAATA
  TCTCCCTGAGGAAAAAAGGGAAATAACCCCAAGCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003369
• Insert Size: 3370 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_003369.2, NP_003360.2
• RefSeq Size: 3515 bp
• RefSeq ORF: 2100 bp
• Locus ID: 7405
• UniProt ID: Q9P2Y5
• Cytogenetics: 11q13.5
• Domains: C2
• Gene Summary: This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008]