FCGRT (NM_004107) Human Untagged Clone

CAT#: SC117595

FCGRT (untagged)-Human Fc fragment of IgG, receptor, transporter, alpha (FCGRT), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FCGRT
• Synonyms: alpha-chain; FCRN
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117595 sequence for NM_004107 edited (data generated by NextGen Sequencing)
  ATGGGGGTCCCGCGGCCTCAGCCCTGGGCGCTGGGGCTCCTGCTCTTTCTCCTTCCTGGG
  AGCCTGGGCGCAGAAAGCCACCTCTCCCTCCTGTACCACCTTACCGCGGTGTCCTCGCCT
  GCCCCGGGGACTCCTGCCTTCTGGGTGTCCGGCTGGCTGGGCCCGCAGCAGTACCTGAGC
  TACAATAGCCTGCGGGGCGAGGCGGAGCCCTGTGGAGCTTGGGTCTGGGAAAACCAGGTG
  TCCTGGTATTGGGAGAAAGAGACCACAGATCTGAGGATCAAGGAGAAGCTCTTTCTGGAA
  GCTTTCAAAGCTTTGGGGGGAAAAGGTCCCTACACTCTGCAGGGCCTGCTGGGCTGTGAA
  CTGGGCCCTGACAACACCTCGGTGCCCACCGCCAAGTTCGCCCTGAACGGCGAGGAGTTC
  ATGAATTTCGACCTCAAGCAGGGCACCTGGGGTGGGGACTGGCCCGAGGCCCTGGCTATC
  AGTCAGCGGTGGCAGCAGCAGGACAAGGCGGCCAACAAGGAGCTCACCTTCCTGCTATTC
  TCCTGCCCGCACCGCCTGCGGGAGCACCTGGAGAGGGGCCGCGGAAACCTGGAGTGGAAG
  GAGCCCCCCTCCATGCGCCTGAAGGCCCGACCCAGCAGCCCTGGCTTTTCCGTGCTTACC
  TGCAGCGCCTTCTCCTTCTACCCTCCGGAGCTGCAACTTCGGTTCCTGCGGAATGGGCTG
  GCCGCTGGCACCGGCCAGGGTGACTTCGGCCCCAACAGTGACGGATCCTTCCACGCCTCG
  TCGTCACTAACAGTCAAAAGTGGCGATGAGCACCACTACTGCTGCATTGTGCAGCACGCG
  GGGCTGGCGCAGCCCCTCAGGGTGGAGCTGGAATCTCCAGCCAAGTCCTCCGTGCTCGTG
  GTGGGAATCGTCATCGGTGTCTTGCTACTCACGGCAGCGGCTGTAGGAGGAGCTCTGTTG
  TGGAGAAGGATGAGGAGTGGGCTGCCAGCCCCTTGGATCTCCCTTCGTGGAGACGACACC
  GGGGTCCTCCTGCCCACCCCAGGGGAGGCCCAGGATGCTGATTTGAAGGATGTAAATGTG
  ATTCCAGCCACCGCCTGA
  
  Clone variation with respect to NM_004107.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004107 unedited
  NTTGTTCGAATTTTGGTATACGACTCACTATAGGGCGGCCGGCGAATCGGCACGAGCCGC
  AGGCAGGAAGGGAGCGAGGCTGAAGGGAACGTCGTCCTCTCAGCATGGGGGTCCCGCGGC
  CTCAGCCCTGGGCGCTGGGGCTCCTGCTCTTTCTCCTTCCTGGGAGCCTGGGCGCAGAAA
  GCCACCTCTCCCTCCTGTACCACCTTACCGCGGTGTCCTCGCCTGCCCCGGGGACTCCTG
  CCTTCTGGGTGTCCGGCTGGCTGGGCCCGCAGCAGTACCTGAGCTACAATAGCCTGCGGG
  GCGAGGCGGAGCCCTGTGGAGCTTGGGTCTGGGAAAACCAGGTGTCCTGGTATTGGGAGA
  AAGAGACCACAGATCTGAGGATCAAGGAGAAGCTCTTTCTGGAAGCTTTCAAAGCTTTGG
  GGGGAAAAGGTCCCTACACTCTGCAGGGCCTGCTGGGCTGTGAACTGGGCCCTGACACAC
  CTCCTCGTGGCCCACCGCCAAGTTCGCCCTGAACGGCGAGGAGTTCATGAATTTCGACCT
  CAAGCAGGGCCCTGGGGTGGGGGACTGCCCCGAGGCCCTGGCTATCAGTCAGCGGTGGCA
  GCAGCAGGACAAGGCGGCCAACAAGGAGCTCACCTTCCTGCTATTCTCCTGCCCGCACCG
  CCTGCGGGAGCACCTGGAAGAGGGGCCCGCCGGAACCCTGGAGTGGGAAAGGAGCCCCCT
  CCATGCGCCTGAAGGCCCGACCCAGCAGCCCTGGCTTTTTCCGTGCTTACCTGCAGCGCC
  TTCTCCTTCTACCCTNCGGAGCTGCACTTTCGGGTCCTGCGGAATGGGCTGGCCGTTGCA
  CCGGCCAGGGGACTTCGGCCCCACGGGGACGGTCCTTCCCGCTTCGTCGCCCTAACGTCA
  AAGCGGCCGAGATCCCCCTCTGCTGCATTGGCCCCAGGGGGCTTGGCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004107 unedited
  ATGAACCGCGGCACGCAATCTAGTAGTCGAGNNNTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGGGGCCCCAAACTTGT
  GTTTTTTTTTGGGGGGGAAAAACCCCCTTTTTTTTTAGGGGGGGAAATTGGGGCAAACCA
  CAGGACGGGGCTCCAAAGGGAGAAAAATTAGCCCCAAAACCCCTTTTGGAGGCTAAAAAA
  TCCCAGGGTTCCAAAAGGTCTAAAAAAAAAAAAGGGGCCTGACTACTTTCTTTTTTAACA
  ACCAAAATGGCGGATGGCCAGGCGGGGGCGGAAATCAAATTTACTTCCTTAAAAAAAAAA
  TCCGGGCCCCCCCCTGGGGGGGGCAGAAAAACCCCGGGGTCTCCCCCAAAAAGGGAAACC
  CAAGGGGGTGGAACCCCATTCTTTTTTTTTTTCAAAAAAAAAATTCCTCCTAAAGCCCTT
  GCCGGGATTAACAAAACCCCGTTAACAATCCCCCCCCCAACCCCGGAGGATTGGGCTGGA
  AATTCCACCTCCACCCTGAGGGGCTGCCCCACCCCCGGGTGTTGAAAAATGAAAAAGTAG
  GGGGCCTCATCCCCCCTTTTAACTGTAAAGGACAACAAGGCGGGAAAGGACCCGCCCTTG
  GGGGGGCCAAATTCACCCTTGGCGGGGCCAGGGGCCACCCCATTCCGAAGAACCCAATTT
  CCCCCTCCGAAGGAAAAAAGAAAAGGCCCTCCAGGTAACCCGGAAAAACCAGGCTGTTGG
  GTCGGCCCTAAGGCACATGGAGGGGGCCTCCTCCCATCAAGGTTCCGGGCCCCTTCAAAG
  GCTCCCCGGGCGGGGGGGAGAAAATACAGAAGGGGCCTCTTTTGCCCCTTTTCTTTTTTC
  CCCCTTAATAAACCAGGCCTGGGCAACCCCCCCAGGGCCGTGTTAGGGGAATTTAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004107
• Insert Size: 1410 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004107.3, NP_004098.1
• RefSeq Size: 1510 bp
• RefSeq ORF: 1098 bp
• Locus ID: 2217
• UniProt ID: P55899
• Cytogenetics: 19q13.33
• Domains: MHC_I, IGc1
• Protein Families: Transmembrane
• Gene Summary: This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
  Transcript Variant: This variant (2) has an alternate 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.