Cyclin G2 (CCNG2) (NM_004354) Human Untagged Clone

CAT#: SC117452

CCNG2 (untagged)-Human cyclin G2 (CCNG2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Cyclin G2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117452 sequence for NM_004354 edited (data generated by NextGen Sequencing)
  ATGAAGGATTTGGGGGCAGAGCACTTGGCAGGTCATGAAGGGGTCCAACTTCTCGGGTTG
  TTGAACGTCTACCTGGAACAAGAAGAGAGATTCCAACCTCGAGAAAAAGGGCTGAGTTTG
  ATTGAGGCTACCCCGGAGAATGATAACACTTTGTGTCCAGGATTGAGAAATGCCAAAGTT
  GAAGATTTAAGGAGTTTAGCCAACTTTTTTGGATCTTGCACTGAAACTTTTGTCCTGGCT
  GTCAATATTTTGGACAGGTTCTTGGCTCTTATGAAGGTGAAACCTAAACATTTGTCTTGC
  ATTGGAGTCTGTTCTTTTTTGCTGGCTGCTAGAATAGTTGAAGAAGACTGCAATATTCCA
  TCCACTCATGATGTGATCCGGATTAGTCAGTGTAAATGTACTGCTTCTGACATAAAACGG
  ATGGAAAAAATAATTTCAGAAAAATTGCACTATGAATTGGAAGCTACTACTGCCTTAAAC
  TTTTTGCACTTATACCATACTATTATACTTTGTCATACTTCAGAAAGGAAAGAAATACTG
  AGCCTTGATAAACTAGAAGCTCAGCTGAAAGCTTGCAACTGCCGACTCATCTTTTCAAAA
  GCAAAACCATCTGTATTAGCCTTGTGCCTTCTCAATTTGGAAGTGGAAACTTTGAAATCT
  GTTGAATTACTGGAAATTCTCTTGCTAGTTAAAAAACATTCCAAGATTAATGACACTGAG
  TTCTTCTACTGGAGAGAGTTGGTTTCTAAATGCCTAGCCGAGTATTCTTCTCCTGAATGT
  TGCAAACCAGATCTTAAGAAGTTGGTTTGGATCGTTTCAAGGCGCACAGCCCAGAACCTC
  CACAACAGCTACTATAGTGTTCCTGAGCTGCCAACGATACCTGAGGGGGGTTGTTTTGAT
  GAAAGTGAAAGTGAGGACTCTTGTGAAGATATGAGTTGTGGAGAGGAGAGTCTCAGCAGC
  TCTCCTCCCAGTGATCAAGAGTGCACCTTCTTTTTCAACTTCAAAGTGGCACAAACACTG
  TGCTTTCCATCTTAG
  
  Clone variation with respect to NM_004354.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004354 unedited
  AACATTTGTATACGACTCACTATAGGCGGCCCGCGAATTCGCACGAGGGTCGGATGCCGG
  ACCGGGGGCACCGCTGAGGCGGTGGGTCCCCGACCTGCGAGACAGGTTTGGAAGCCCCCG
  CTGCGCCCAGTCCGTGCGGACCGCGAGGCCGCGGGCGGGTGGAGGCGCGTCTCCGGCACG
  ATGAAGGATTTGGGGGCAGAGCACTTGGCAGGTCATGAAGGGGTCCAACTTCTCGGGTTG
  TTGAACGTCTACCTGGAACAAGAAGAGAGATTCCAACCTCGAGAAAAAGGGCTGAGTTTG
  ATTGAGGCTACCCCGGAGAATGATAACACTTTGTGTCCAGGATTGAGAAATGCCAAAGTT
  GAAGATTTAAGGAGTTTAGCCAACTTTTTTGGATCTTGCACTGAAACTTTTGTCCTGGCT
  GTCAATATTTTGGACAGGTTCTTGGCTCTTATGAAGGTGAAACCTAAACATTTGTCTTGC
  ATTGGAGTCTGTTCTTTTTTGCTGGCTGCTAGAATAGTTGAAGAAGACTGCAATATTCCA
  TCCACTCATGATGTGATCCGGATTAGTCAGTGTAAATGTACTGCTTCTGACATAAAACGG
  ATGGAAAAAATAATTTCAGAAAAATTGCACTATGAATTGGAAGCTACTACTGCCTTANAC
  TTTNTGCACTTATACCATACTATTATACTTTGNNCATACTTCAGAAAGGAAAGAAATACC
  TGAGCCTTGATAAACTAGAAGCTCAGCTGANAGCTTNGCACTGCCGACTCATCTTTTCAA
  AGCAAACCATCTGTATTAGCCTTGTGCCTTCTCATNNTGGAGTGGGAACTTTTGAATCTG
  TTGAATACTGGNAATTCTCTTGCTANTAAANA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004354 unedited
  GTACGCGGCCGCAATCTAGAGTCGAGCCCTTCTTTTTTTTTTTTTTTTTTTTTTGAGAAT
  TCATTAATAATTTTATTTTGAATTACAATCTATTATCACTTCAAAAAGAGCCACTTCAGA
  AAACATTCAACGGATGTTGACTTACCAGTAAAAATGTAAGTCATCAATGTATGATTTATA
  CTACAGAATACATAATAAATTATATTTACATGCAATGACTAGACTATCACACACAAGGGA
  AAAAAATACAGCATTTTATGTACATTTTAAAAGATTTACATGTTCATATACAATTTATAA
  AGTTAAAAATTNTTTGTACAAAATCTTACATGTACAGAGTTTATATAAGCCCCATTCTTA
  TGGCTGTATCACCACACAGATTTGCTTAAAACTATAATACTACAAACACTCGGGTTCTTT
  ATATTCAATCTTGGCACCCATATAGCAATACACTATTCTGAAATGCAAATTACAAAGGAA
  ATAAAATGTAATCATGCAGACATTTTTTAATATAAGAAAATGCGATAAAATATACCTACA
  CCAGATCAACATTTATCAATCCCATAGACACTGAGTTTTCAACTTACTGCACTGTTTTCA
  TACTAGTCCCTGCAAAACTAGCAGATTATGGATTTTTAAACGAACACTTAAAATAATTCC
  CCTATTTTTGACAATACCTGGGCCATTAGGCAATGAAACCTAAAAGCCCTTACCCAATTA
  TTTCTTGCCTTAACCAGAATNTTTATTTAAGACTTTCCCTCATTTANAAAGACCGGCATG
  TGCCACATTATAATTTCCAATTTTTAAGATATTGGTTACCATCAAAAAAACTGATTATTT
  AAAAAACACACCACCCACAGGGTTTGAATTTAAGACCTACTCACTTTTTGTAAGGGGGCA
  GGTGAATCTGTATACCCTTCGATTTCCCTGTCCTGGTAGAAGACTTGCACCTCAACTGCT
  AAAAATTTGAAGTTTTAAAGCTACAAACCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004354
• Insert Size: 2560 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004354.1, NP_004345.1
• RefSeq Size: 2044 bp
• RefSeq ORF: 1035 bp
• Locus ID: 901
• UniProt ID: Q16589
• Cytogenetics: 4q21.1
• Domains: CYCLIN, cyclin
• Protein Families: Druggable Genome
• Protein Pathways: p53 signaling pathway
• Gene Summary: The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle. [provided by RefSeq, Jul 2008]