CCXCR1 (XCR1) (NM_005283) Human Untagged Clone

CAT#: SC116839

XCR1 (untagged)-Human chemokine (C motif) receptor 1 (XCR1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CCXCR1
• Synonyms: CCXCR1; GPR5
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116839 sequence for NM_005283 edited (data generated by NextGen Sequencing)
  ATGGAGTCCTCAGGCAACCCAGAGAGCACCACCTTTTTTTACTATGACCTTCAGAGCCAG
  CCGTGTGAGAACCAGGCCTGGGTCTTTGCTACCCTCGCCACCACTGTCCTATACTGCCTG
  GTGTTTCTCCTCAGCCTAGTGGGCAACAGCCTGGTCCTGTGGGTCCTGGTGAAGTATGAG
  AGCCTGGAGTCCCTCACCAACATCTTCATCCTCAACCTGTGCCTCTCAGACCTGGTGTTC
  GCCTGCTTGTTGCCTGTGTGGATCTCCCCATACCACTGGGGCTGGGTGCTGGGAGACTTC
  CTCTGCAAACTCCTCAATATGATCTTCTCCATCAGCCTCTACAGCAGCAGCTTCTTCCTG
  ACCATCATGACCATCCACCGCTACCTGTCGGTAGTGAGCCCCCTCTCCACCCTGCGCGTC
  CCCACCCTCCGCTGCCGGGTGCTGGTGACCATGGCTGTGTGGGTAGCCAGCATCCTGTCC
  TCCATCCTCGACACCATCTTCCACAAGGTGCTTTCTTCGGGCTGTGATTATTCCGAACTC
  ACGTGGTACCTCACCTCCGTCTACCAGCACAACCTCTTCTTCCTGCTGTCCCTGGGGATT
  ATCCTGTTCTGCTACGTGGAGATCCTCAGGACCCTGTTCCGCTCACGCTCCAAGCGGCGC
  CACCGCACGGTCAAGCTCATCTTCGCCATCGTGGTGGCCTACTTCCTCAGCTGGGGTCCC
  TACAACTTCACCCTGTTTCTGCAGACGCTGTTTCGGACCCAGATCATCCGGAGCTGCGAG
  GCCAAACAGCAGCTAGAATACGCCCTGCTCATCTGCCGCAACCTCGCCTTCTCCCACTGC
  TGCTTTAACCCGGTGCTCTATGTCTTCGTGGGGGTCAAGTTCCGCACACACCTGAAACAT
  GTTCTCCGGCAGTTCTGGTTCTGCCGGCTGCAGGCACCCAGCCCAGCCTCGATCCCCCAC
  TCCCCTGGTGCCTTCGCCTATGAGGGCGCCTCCTTCTACTGA
  
  Clone variation with respect to NM_005283.2
  350 t=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005283 unedited
  TTTGGGCCAATTACGGGATTTGTNAAACGATTTACTATAGGCGGCCGCCAGTCGTGATGG
  AATCTGCAGAATCGCCCTTATGGAGTCCTCAGGCAACCCAGAGAGCACCACCTTTTTTTA
  CTATGACCTTCAGAGCCAGCCGTGTGAGAACCAGGCCTGGGTCTTTGCTACCCTCGCCAC
  CACTGTCCTATACTGCCTGGTGTTTCTCCTCAGCCTAGTGGGCAACAGCCTGGTCCTGTG
  GGTCCTGGTGAAGTATGAGAGCCTGGAGTCCCTCACCAACATCTTCATCCTCAACCTGTG
  CCTCTCAGACCTGGTGTTCGCCTGCTTGTTGCCTGTGTGGATCTCCCCATACCACTGGGG
  CTGGGTGCTGGGAGACTTCCTCTGCAAACTCCTCAATATGATCTTCTCCATCAGCCTCTA
  CAGCAGCAGCTTCTTCCTGACCATCATGACCATCCACCGCTACCTGTCGGTAGTGAGCCC
  CCTCTCCACCCTGCGCGTCCCCACCCTCCGCTGCCGGGTGCTGGTGACCATGGCTGTGTG
  GGTAGCCAGCATCCTGTCCTCCATCCTCGACACCATCTTCCACAAGGTGCTTTCTTCGGG
  CTGTGATTATTCCGAACTCACGTGGTACCTCACCTCCGTCTACCAGCACAACCTCTTCTT
  CCTGCTGTCCCTGGGGATTATCCTGTTCTGCTACGTGGAGATCCTCANGACCCTGTTCCG
  CTCACGCTCCAAGCGGCGCCACCGCACGGTCAAGCTCATCTTCGACATCGTGGTGGCCTA
  CTTCCTCAGCTGGGTCCCTACAACTTCACCCTGTTTCTGCAGACGCTGTTTCGGGACCCA
  GATCATCCCGGAGCTGCG
  
• Restriction Sites: Please inquire
• ACCN: NM_005283
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005283.2, NP_005274.1
• RefSeq Size: 1373 bp
• RefSeq ORF: 1002 bp
• Locus ID: 2829
• UniProt ID: P46094
• Cytogenetics: 3p21.31
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction
• Gene Summary: The protein encoded by this gene is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Several alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2020]
  Transcript Variant: This variant (1) represents the longer transcript.