IGF2BP2 (NM_006548) Human Untagged Clone

CAT#: SC116032

IGF2BP2 (untagged)-Human insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IGF2BP2
• Synonyms: IMP-2; IMP2; VICKZ2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116032 sequence for NM_006548 edited (data generated by NextGen Sequencing)
  ATGATGAACAAGCTTTACATCGGGAACCTGAGCCCCGCCGTCACCGCCGACGACCTCCGG
  CAGCTCTTTGGGGACAGGAAGCTGCCCCTGGCGGGACAGGTCCTGCTGAAGTCCGGCTAC
  GCCTTCGTGGACTACCCCGACCAGAACTGGGCCATCCGCGCCATCGAGACCCTCTCGGGT
  AAAGTGGAATTGCATGGGAAAATCATGGAAGTTGATTACTCAGTCTCTAAAAAGCTAAGG
  AGCAGGAAAATTCAGATTCGAAACATCCCTCCTCACCTGCAGTGGGAGGTGTTGGATGGA
  CTTTTGGCTCAATATGGGACAGTGGAGAATGTGGAACAAGTCAACACAGACACAGAAACC
  GCCGTTGTCAACGTCACATATGCAACAAGAGAAGAAGCAAAAATAGCCATGGAGAAGCTA
  AGCGGGCATCAGTTTGAGAACTACTCCTTCAAGATTTCCTACATCCCGGATGAAGAGGTG
  AGCTCCCCTTCGCCCCCTCAGCGAGCCCAGCGTGGGGACCACTCTTCCCGGGAGCAAGGC
  CACGCCCCTGGGGGCACTTCTCAGGCCAGACAGATTGATTTCCCGCTGCGGATCCTGGTC
  CCCACCCAGTTTGTTGGTGCCATCATCGGAAAGGAGGGCTTGACCATAAAGAACATCACT
  AAGCAGACCCAGTCCCGGGTAGATATCCATAGAAAAGAGAACTCTGGAGCTGCAGAGAAG
  CCTGTCACCATCCATGCCACCCCAGAGGGGACTTCTGAAGCATGCCGCATGATTCTTGAA
  ATCATGCAGAAAGAGGCAGATGAGACCAAACTAGCCGAAGAGATTCCTCTGAAAATCTTG
  GCACACAATGGCTTGGTTGGAAGACTGATTGGAAAAGAAGGCAGAAATTTGAAGAAAATT
  GAACATGAAACAGGGACCAAGATAACAATCTCATCTTTGCAGGATTTGAGCATATACAAC
  CCGGAAAGAACCATCACTGTGAAGGGCACAGTTGAGGCCTGTGCCAGTGCTGAGATAGAG
  ATTATGAAGAAGCTGCGTGAGGCCTTTGAAAATGATATGCTGGCTGTTAACCAACAAGCC
  AATCTGATCCCAGGGTTGAACCTCAGCGCACTTGGCATCTTTTCAACAGGACTGTCCGTG
  CTATCTCCACCAGCAGGGCCCCGCGGAGCTCCCCCCGCTGCCCCCTACCACCCCTTCACT
  ACCCACTCCGGATACTTCTCCAGCCTGTACCCCCATCACCAGTTTGGCCCGTTCCCGCAT
  CATCACTCTTATCCAGAGCAGGAGATTGTGAATCTCTTCATCCCAACCCAGGCTGTGGGC
  GCCATCATCGGGAAGAAGGGGGCACACATCAAACAGCTGGCGAGATTCGCCGGAGCCTCT
  ATCAAGATTGCCCCTGCGGAAGGCCCAGACGTCAGCGAAAGGATGGTCATCATCACCGGG
  CCACCGGAAGCCCAGTTCAAGGCCCAGGGACGGATCTTTGGGAAACTGAAAGAGGAAAAC
  TTCTTTAACCCCAAAGAAGAAGTGAAGCTGGAAGCGCATATCAGAGTGCCCTCTTCCACA
  GCTGGCCGGGTGATTGGCAAAGGTGGCAAGACCGTGAACGAACTGCAGAACTTAACCAGT
  GCAGAAGTCATCGTGCCTCGTGACCAAACGCCAGATGAAAATGAGGAAGTGATCGTCAGA
  ATTATCGGGCACTTCTTTGCTAGCCAGACTGCACAGCGCAAGATCAGGGAAATTGTACAA
  CAGGTGAAGCAGCAGGAGCAGAAATACCCTCAGGGAGTCGCCTCACAGCGCAGCAAGTGA
  
  Clone variation with respect to NM_006548.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006548 unedited
  GCATTTTGTAATACGACTCACTATAGGGCGGCCCGCGAATTCGCACGAGGGCGGAGGAGG
  AGGAGAGACGAGGGCAGCGGAGGAGGCGAGGAGCGCCGGGTACCGGGCCGGGGGAGCCGC
  GGGCTCTCGGGGAAGAGACGGATGATGAACAAGCTTTACATCGGGAACCTGAGCCCCGCC
  GTCACCGCCGACGACCTCCGGCAGCTCTTTGGGGACAGGAAGCTGCCCCTGGCGGGACAG
  GTCCTGCTGAAGTCCGGCTACGCCTTCGTGGACTACCCCGACCAGAACTGGGCCATCCGC
  GCCATCGAGACCCTCTCGGGTAAAGTGGAATTGCATGGGAAAATCATGGAAGTTGATTAC
  TCAGTCTCTAAAAAGCTAAGGAGCAGGAAAATTCAGATTCGAAACATCCCTCCTCACCTG
  CAGTGGGAGGTGTTGGATGGACTTTTGGCTCAATATGGGACAGTGGAGAATGTGGAACAA
  GTCAACACAGACACAGAAACCGCCGTTGTCAACGTCACATATGCAACAAGAGAAGAAGCA
  AAAATAGCCATGGAGAAGCTAAGCGGGCATCAGTTTGAGAACTACTCCTTCAAGATTTCC
  TACATCCCGGATGAAGAGGTGAGCTCCCCTTCGCCCCCTCAGCGAGCCCAGCGTGGGGAC
  CACTCTTCCCGGGAGCAAGGCCACGCCCCTGGGGGCACTTCTCAGGCCAGACAGATTGAT
  TTCCCGCTGCGGATCCTGGTCCCCACCCAGTTNGTTGGTGCCATCATCNGAAAGGGAGGC
  TTGACCATAAAGAACATCACTAAGCAGACCCAGTCCCGGGTAGATATCCATAGAAAAGAA
  GACTCTGGAGCTGCAGAGAAGCCTGTCACCATCCATGCCACCCCAGAGGGGGACTCTGAA
  GCATGCCGCATGATTCTTGAAATCTGCCGAAGAGGCAGAGAGACCCACTAGCCGAGAGAT
  CCTCTGAANATCTGCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006548 unedited
  TTCCTCTGCNACCGCGGCCGCAATCTAGNAGTCGAGTTTTTTTTTTTTTTTTTTAAATAA
  ACATTTTCAAGGTTTGTCCAAAAGAAGCCATATAGGTTCTTGGCTAGCGGAAGACAATTC
  AGAACAGCTGTTGCACACTTGGACTGCCACCTTCTCCAGGCTGGCAGTTGATATCTTATT
  TTTTTTCCAACTCATTTTTATTAAAAAAATAAAAAAATGCTCCAACTATCAGCTTCACAA
  AATCTCTAAGGGAAACACAAGAGCAAGGCGCTGAGGTAAAAACACCTGAGGCAGCTTCTT
  CTGTGTGTTTTTCTCGTTAAAAAAATCTGTGAATTTAACGCCCTGGGCCAACAACCTTGG
  CCACCTTCTACTTTCCTCCCCACTCTCTTTCCCTATCGAAAGGCCCCACTCTGCTGAACC
  TCGACGGCTTATCCCCCACTACGCACCTCCACCCCTCCACTCCCTCCTTTTGGCCATTCT
  TCTTTGCTCCGCTGCACCCCCGCCTCTCCCCTCCCCCCCCCCCCCCTACTCATCATACTT
  TTTCCATCACTATACTTCTCTCTCTCCCCCTTTTCCCCCTCCCCCCTCCTCCTTTTTCTT
  CCCTCTTTTCCCTTCTCCCTTTCCTCCCCCCCCATCAAAATAAAATAGAACGTTTACCTT
  ATCCCTCTACACCCCCTCCCTTCCCCCTCCCCACCACCAATTTTAATTTTCAATCCCTCC
  CCTTTCTTTCACCTTCCCATCACGACCGTTAATCTCCCCTCTAACACCCCCTTCCTAATT
  TTCACCCCCTCCTTCTCTCCACCTCCTCCTCCATCTCTCCTTCCCCTCTTCGTCTACCCT
  ATCCCCCCCCCGCCCCCTCCTCCCATTCCCCCTCCCCTCCACCCCCCCCATTTATATTTT
  TCCACCCCTCCCCCGCTCCCCCTCCCCCCCCCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006548
• Insert Size: 3520 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006548.4, NP_006539.3
• RefSeq Size: 3676 bp
• RefSeq ORF: 1800 bp
• Locus ID: 10644
• UniProt ID: Q9Y6M1
• Cytogenetics: 3q27.2
• Domains: RRM, KH
• Gene Summary: This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative splicing and promoter usage results in multiple transcript variants. Related pseudogenes are found on several chromosomes. [provided by RefSeq, Sep 2016]