ANGPTL2 (NM_012098) Human Untagged Clone

CAT#: SC115544

ANGPTL2 (untagged)-Human angiopoietin-like 2 (ANGPTL2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ANGPTL2
• Synonyms: ARP2; HARP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115544 sequence for NM_012098 edited (data generated by NextGen Sequencing)
  ATGAGGCCACTGTGCGTGACATGCTGGTGGCTCGGACTGCTGGCTGCCATGGGAGCTGTT
  GCAGGCCAGGAGGACGGTTTTGAGGGCACTGAGGAGGGCTCGCCAAGAGAGTTCATTTAC
  CTAAACAGGTACAAGCGGGCGGGCGAGTCCCAGGACAAGTGCACCTACACCTTCATTGTG
  CCCCAGCAGCGGGTCACGGGTGCCATCTGCGTCAACTCCAAGGAGCCTGAGGTGCTTCTG
  GAGAACCGAGTGCATAAGCAGGAGCTAGAGCTGCTCAACAATGAGCTGCTCAAGCAGAAG
  CGGCAGATCGAGACGCTGCAGCAGCTGGTGGAGGTGGACGGCGGCATTGTGAGCGAGGTG
  AAGCTGCTGCGCAAGGAGAGCCGCAACATGAACTCGCGGGTCACGCAGCTCTACATGCAG
  CTCCTGCACGAGATCATCCGCAAGCGGGACAACGCGTTGGAGCTCTCCCAGCTGGAGAAC
  AGGATCCTGAACCAGACAGCCGACATGCTGCAGCTGGCCAGCAAGTACAAGGACCTGGAG
  CACAAGTACCAGCACCTGGCCACACTGGCCCACAACCAATCAGAGATCATCGCGCAGCTT
  GAGGAGCACTGCCAGAGGGTGCCCTCGGCCAGGCCCGTCCCCCAGCCACCCCCCGCTGCC
  CCGCCCCGGGTCTACCAACCACCCACCTACAACCGCATCATCAACCAGATCTCTACCAAC
  GAGATCCAGAGTGACCAGAACCTGAAGGTGCTGCCACCCCCTCTGCCCACTATGCCCACT
  CTCACCAGCCTCCCATCTTCCACCGACAAGCCGTCGGGCCCATGGAGAGACTGCCTGCAG
  GCCCTGGAGGATGGCCACGACACCAGCTCCATCTACCTGGTGAAGCCGGAGAACACCAAC
  CGCCTCATGCAGGTGTGGTGCGACCAGAGACACGACCCCGGGGGCTGGACCGTCATCCAG
  AGACGCCTGGATGGCTCTGTTAACTTCTTCAGGAACTGGGAGACGTACAAGCAAGGGTTT
  GGGAACATTGATGGCGAATACTGGCTGGGCCTGGAGAACATTTACTGGCTGACGAACCAA
  GGCAACTACAAACTCCTGGTGACCATGGAGGACTGGTCCGGCCGCAAAGTCTTTGCAGAA
  TACGCCAGTTTCCGCCTGGAACCTGAGAGCGAGTATTATAAGCTGCGGCTGGGGCGCTAC
  CATGGCAATGCGGGTGACTCCTTTACATGGCACAACGGCAAGCAGTTCACCACCCTGGAC
  AGAGATCATGATGTCTACACAGGAAACTGTGCCCACTACCAGAAGGGAGGCTGGTGGTAT
  AACGCCTGTGCCCACTCCAACCTCAACGGGGTCTGGTACCGCGGGGGCCATTACCGGAGC
  CGCTACCAGGACGGAGTCTACTGGGCTGAGTTCCGAGGAGGCTCTTACTCACTCAAGAAA
  GTGGTGATGATGATCCGACCGAACCCCAACACCTTCCACTAA
  
  Clone variation with respect to NM_012098.2
  1032 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012098 unedited
  GTCANGATTTGTATACGACTTATATAGGGCGGCCGCGAATTCGCACGAGGAGCATGTGAG
  GAGCCGCCCCGNGACCAAGCAGGAGGGAAGAGGCTTTCATAGATTCTATTCACAAAGAAT
  AACCACCATTTTGCAAGGACCATGAGGCCACTGTGCGTGACATGCTGGTGGCTCGGACTG
  CTGGCTGCCATGGGAGCTGTTGCAGGCCAGGAGGACGGTTTTGAGGGCACTGAGGAGGGC
  TCGCCAAGAGAGTTCATTTACCTAAACAGGTACAAGCGGGCGGGCGAGTCCCAGGACAAG
  TGCACCTACACCTTCATTGTGCCCCAGCAGCGGGTCACGGGTGCCATCTGCGTCAACTCC
  AAGGAGCCTGAGGTGCTTCTGGAGAACCGAGTGCATAAGCAGGAGCTAGAGCTGCTCAAC
  AATGAGCTGCTCAAGCAGAAGCGGCAGATCGAGACGCTGCAGCAGCTGGTGGAGGTGGAC
  GGCGGCATTGTGAGCGAGGTGAAGCTGCTGCGCAAGGAGAGCCGCAACATGAACTCGCGG
  GTCACGCAGCTCTACATGCAGCTCCTGCACGAGATCATCCGCAAGCGGGACAACGCGTTG
  GAGCTCTCCCAGCTGGAGAACAGGATCCTGAACCAGACAGCCGACATGCTGCAGCTGGCC
  AGCAAGTACAAGGACCTGGAGCACAAGTACCAGCACCTGGCCACACTGGCCCACAACCAA
  TCAGAGATCATCGCGCAGCTTGAGGAGCACTGCCAGAGGGTGCCCTCGGCCAGGGCCCCG
  TCCCCCAGCCACCCCCCGCTTGCCCCGCCCCCGGGTCTACCAACCACCCACCTACCACCG
  CATCATCAACCAGATCTCTACCAACGAGATTCAGAGTGACCAAACCCGGGAAGGTGCTGC
  CCCCCCCTCTGGCCCACTATTGCCACTTTCACCA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_012098 unedited
  CGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTACATCCAAATAGCACTGATGG
  CTTTTATTGCAGATTCGTGTCATTACAAGGATAATCTGGGAATATATTTTTAAAAAAACC
  CTCCCTTTTATATACACAAAACATGCTACATGGTACACTTTGTGAGAAATGCTGAGGTAA
  TAGGCACACACCCAGACATGGACAGTACCAAACATCCAACATCTCACACAGCCTGGCCCA
  CGTGCCCACCGGGAAGGGTCTCACCTTCTTGACTCATCCCTTGCCCCTTCTTGGCAATAG
  TTCCGGGAGTGCTGAGGCTGACACTTGGTGGCCAACAGGACTCAGAAAGCCACCATGCTG
  CAGTGCATCAACCAAGGGGTCCGGTGACCCCTGATTATTCAACTCCTGAGAAGTGGCCTG
  TTTTCATTTTTGTGGCACTTGTTCTCCAGGGAAGTGTAGTTTGGAGATGAGATGCGGACT
  CTAGTCAGCCTGAGAGCGTGGAATCTCTGGTCTGTAGCCATCTGGGGGCTCTGATGATCT
  GATGACTTCTGTTCTGAGATAATTCTCCTGGCCAGATAGGTTATTATTTGTGCGAAGACT
  CAAATGACCTGTAGGTTAAAGTATGAATGGAAGATACAAAACTGCGAGTACATTATCTAT
  ACGGCCGGTGGAGCCTTTGGGCTGCCCTCTCCTTCCCACCAGAAACCTGCAGCCCGGAGT
  GTTTCCTACTTAGAAGCTGAGGAATCTCCCCTGGAAAGAAGGGCTGTGCGACAGAATACG
  CAAGGAGTACGTACGCGAGGATACAACACCACGGAAGGGGGCCCTGACATGCATGAGTGC
  CCCCGCACTGACCCACACAAGCACCTAATGAATGGCGTCAATGAACGATAANGGGTGAAG
  GAGGCGAAACANTCCCAAATGGGAATAGTCACATGTGGGGCCGGTTTCAACTTTTATGTC
  CCAAGCGTCT
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_012098
• Insert Size: 3100 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_012098.2, NP_036230.1
• RefSeq Size: 3572 bp
• RefSeq ORF: 1482 bp
• Locus ID: 23452
• UniProt ID: Q9UKU9
• Cytogenetics: 9q33.3
• Domains: FBG
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
• Gene Summary: Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. ANGPTL2 protein is a secreted glycoprotein with homology to the angiopoietins and may exert a function on endothelial cells through autocrine or paracrine action. [provided by RefSeq, Jul 2008]