LXN (NM_020169) Human Untagged Clone

CAT#: SC113204

LXN (untagged)-Human latexin (LXN)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LXN
• Synonyms: ECI; TCI
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC113204 sequence for NM_020169 edited (data generated by NextGen Sequencing)
  ATGGAAATCCCGCCGACCAACTACCCAGCCTCCAGGGCGGCCTTGGTGGCACAGAACTAC
  ATCAACTACCAGCAGGGGACCCCGCACAGGGTGTTTGAGGTGCAGAAGGTCAAACAAGCC
  AGCATGGAGGATATTCCAGGAAGAGGACATAAGTATCACCTTAAATTTGCTGTTGAAGAA
  ATTATACAAAAACAAGTTAAGGTGAACTGCACAGCTGAAGTACTTTACCCTTCAACGGGA
  CAAGAAACTGCACCAGAAGTCAACTTCACATTTGAAGGAGAAACTGGAAAGAATCCAGAT
  GAAGAAGACAACACATTTTATCAAAGACTTAAGTCCATGAAGGAACCGCTAGAAGCACAA
  AATATTCCAGACAATTTTGGAAATGTATCTCCAGAAATGACGCTCGTTCTACATTTAGCC
  TGGGTTGCCTGTGGTTATATAATATGGCAAAATTCTACTGAAGACACATGGTATAAAATG
  GTAAAAATTCAAACTGTCAAGCAAGTGCAAAGAAATGATGACTTTATTGAATTAGACTAC
  ACCATTCTACTTCATAATATAGCATCTCAGGAGATTATTCCCTGGCAAATGCAAGTTCTC
  TGGCATCCACAATACGGCACTAAAGTAAAACATAATAGCCGTCTGCCAAAGGAAGTACAA
  CTGGAATAA
  
  Clone variation with respect to NM_020169.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020169 unedited
  GGGGGTTGGATTTGTATACGATTCACTATAGGCGGCCGCGAATTCGCACGAGGAGCAGCT
  TCCGGAGTCGGAAGGAGCTGAGGAAGAAGACTGACTGAAGGAGCTTGCGACTTTTCCGCC
  TCGGCAACCGGACCCAGCAGCAAGCAGGACGGGCGGCGCTCTGCTACTGGTCCCGTTAAG
  CCAGAGTAGCCCAAGCCCTGAAGTCACTGCTCATCCGGAATGGAAATCCCGCCGACCAAC
  TACCCAGCCTCCAGGGCGGCCTTGGTGGCACAGAACTACATCAACTACCAGCAGGGGACC
  CCGCACAGGGTGTTTGAGGTGCAGAAGGTCAAACAAGCCAGCATGGAGGATATTCCAGGA
  AGAGGACATAAGTATCACCTTAAATTTGCTGTTGAAGAAATTATACAAAAACAAGTTAAG
  GTGAACTGCACAGCTGAAGTACTTTACCCTTCAACGGGACAAGAAACTGCACCAGAAGTC
  AACTTCACATTTGAAGGAGAAACTGGAAAGAATCCAGATGAAGAAGACAACACATTTTAT
  CAAAGACTTAAGTCCATGAAGGAACCGCTAGAAGCACAAAATATTCCAGACAATTTTGGA
  AATGTATCTCCAGAAATGACGCTCGTTCTACATTTAGCCTGGGTTGCCTGTGGTTATATA
  ATATGGCAAAATTCTACTGAAGACACATGGTATAAAATGGTAAAAATTCAAACTGTCAAG
  CAAGTGCAAAGAAATGATGACTTTATTGAATTAGACTACACCATTCTACTTCATAATATA
  GCATCTCAGGAGATTATNTCCTGGCANATGCAAGTTCTCTGGCATCCACAATACGGCACT
  AAAGTAAAAACATATAGCCGTCTGCCAAAGGAAGTACACTGGAATAAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_020169 unedited
  GAGTCGAGTTTTTTTTTTTTTTTTTTGAGGCTGAAATTGAAGCTTTTTATTTTGGATATA
  CATACCACTATTACTGTTTTAAAGACATTTTTATGTACTGATACTTTGCATTATGGACTC
  TATAAAGCCCTATACTGTAATGAAGACATTCATATAAAGTGACACTTTGGGATTATTTGG
  CCTCATAACCCTACAGGCCGGGAACTAGGGATGCGCATGTTTGCACATGCCAACACTTCT
  ACCGACGGGGGTGGTGCCCATTCGATAAGAACTCGACTTTGTAACACGGCGCTTTTGCCG
  CCCGTCATGCCGCCGTTTTGCGCCCGGCCCCACTGCTTCTTTTTTTTTCCTGACATGTAT
  TAGTGTCACCCACCTTTTTGTTTCTCTCTCCCGCGTTTCGCATTCCGCAACCCGAATCGT
  TTTATATGCAATATGCAAAGCGACCAACAACTTCCACCCCCGTCGTGCCGCGCGAGCGCG
  CCTTGTTTTCACTTTTTTCGCCGTTTCCCCGACCCCACCCCTTTTTTTTGTTTACCATTG
  TGATCTTCGCGGCTCCGCCACCCCCGCCGTGCAGGGGCATCGTCTCTGTTTTCACGCGTT
  TCTCCCCACCTCCGCTTCTTTGTCCCCGCACAACAACCTCCACTCTTTATGTTACCCCTC
  GCCTTCCCCATGCCCACAGTTTTCCTCCCGGCGTTTTTCCCCCCGCCATTTATCACCCGT
  TTCAGCCCTCTCATATAGTGTAAGAACTCGACGCTCGCGGTCGGACGGGCGAGACGAACG
  TAGTTTGACGACGTTCATCTCGTATGCCGGCGTTATCGCCGGCCGCGCGTAATATTTTTA
  TTCCCCCGCCCTACCGGTACGCCCGCCAGATTGTCCCCCCTAGTAATGGACGCTCCCCCC
  CCCCACGACGCATCTAAGTGTACGGTACGGTACGCAAGAGGTCCCGCCATGAGGAGCGCC
  CACCTATCGGTCGCATAACACACATGTTGTTATAATATGCCCTGCCCCAGCGCTGTTTGG
  TGCGCACCCCCGCGCCCCGCCCGTCACAGTTCTGTNGACGCAGCCGGCCGCTCCCCATCC
  ACTTTAATTN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_020169
• Insert Size: 1100 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_020169.2, NP_064554.2
• RefSeq Size: 1144 bp
• RefSeq ORF: 669 bp
• Locus ID: 56925
• UniProt ID: Q9BS40
• Cytogenetics: 3q25.32
• Gene Summary: This gene encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases. The encoded protein, latexin, downregulates the population size of hematopoietic stem cells. This protein is found to be downregulated in cancer cells because of promoter hypermethylation. [provided by RefSeq, Jul 2020]