FBXO7 (NM_012179) Human Untagged Clone

CAT#: SC112656

FBXO7 (untagged)-Human F-box protein 7 (FBXO7), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FBXO7
• Synonyms: FBX; FBX07; FBX7; PARK15; PKPS
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC112656 sequence for NM_012179 edited (data generated by NextGen Sequencing)
  ATGAGGCTGCGGGTGCGGCTTCTGAAGCGGACCTGGCCGCTGGAGGTGCCCGAGACGGAG
  CCGACGCTGGGGCATTTGCGCTCGCACCTGAGGCAGTCCCTGCTGTGCACCTGGGGGTAC
  AGTTCTAATACCCGATTTACAATTACATTGAACTACAAGGATCCCCTCACTGGAGATGAA
  GAGACCTTGGCTTCATATGGGATTGTTTCTGGGGACTTGATATGTTTGATTCTTCAAGAT
  GACATTCCAGCGCCTAATATACCTTCATCCACAGATTCAGAGCATTCTTCACTCCAGAAT
  AATGAGCAACCCTCTTTGGCCACCAGCTCCAATCAGACTAGCATACAGGATGAACAACCA
  AGTGATTCATTCCAAGGACAGGCAGCCCAGTCTGGTGTTTGGAATGACGACAGTATGTTA
  GGGCCTAGTCAAAATTTTGAAGCTGAGTCAATTCAAGATAATGCGCATATGGCAGAGGGC
  ACAGGTTTCTATCCCTCAGAACCCATGCTCTGTAGTGAATCGGTGGAAGGGCAAGTGCCA
  CATTCATTAGAGACCTTGTATCAATCAGCTGACTGTTCTGATGCCAATGATGCCTTGATA
  GTGTTGATACATCTTCTCATGTTGGAGTCAGGTTACATACCTCAGGGCACCGAAGCCAAA
  GCACTGTCCATGCCGGAGAAGTGGAAGTTGAGCGGGGTGTATAAGCTGCAGTACATGCAT
  CCTCTCTGCGAGGGCAGCTCCGCTACTCTCACCTGTGTGCCTTTGGGAAACCTGATTGTT
  GTAAATGCTACACTAAAAATCAACAATGAGATTAGAAGTGTGAAAAGATTGCAGCTGCTA
  CCAGAATCTTTTATTTGCAAAGAGAAACTAGGGGAAAATGTAGCCAACATATACAAAGAT
  CTTCAGAAACTCTCTCGCCTCTTTAAAGACCAGCTGGTGTATCCTCTTTTGGCTTTTACC
  CGACAAGCACTGAACCTACCAGATGTATTTGGGTTGGTCGTCCTCCCATTGGAACTGAAA
  CTACGGATCTTCCGACTTCTGGATGTTCGTTCCGTCTTGTCTTTGTCTGCGGTTTGTCGT
  GACCTCTTTACTGCTTCAAATGACCCACTCCTGTGGAGGTTTTTATATCTGCGTGATTTT
  CGAGACAATACTGTCAGAGTTCAAGACACAGATTGGAAAGAACTGTACAGGAAGAGGCAC
  ATACAAAGAAAAGAATCCCCGAAAGGGCGGTTTGTGATGCTCCTGCCATCGTCAACTCAC
  ACCATTCCATTCTATCCCAACCCCTTGCACCCTAGGCCATTTCCTAGCTCCCGCCTTCCT
  CCAGGAATTATCGGGGGTGAATATGACCAAAGACCAACACTTCCCTATGTTGGAGACCCA
  ATCAGTTCACTCATTCCTGGTCCTGGGGAGACGCCCAGCCAGTTTCCTCCACTGAGACCA
  CGCTTTGATCCAGTTGGCCCACTTCCAGGACCTAACCCCATCTTGCCAGGGCGAGGCGGC
  CCCAATGACAGATTTCCCTTTAGACCCAGCAGGGGTCGGCCAACTGATGGCCGGCTGTCA
  TTCATGTGA
  
  Clone variation with respect to NM_012179.3
  345 g=>a;949 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012179 unedited
  CTCTACTTTGATTTACTATAGGGCGGCCGCGAATTCGGCACGAGGCTGTGGCGGGTTTCT
  TTCCCCGTTTCGCCTCAGCTACCCCTCAGCTCCGGTAGTCGCCAGTCCGGGGTCGTCGCC
  GTTTGGGGCGGGAGCTGCTCGGCCCCGCCGCCGTCCCCGTCGCCGCTTCCGGGTCCAGGC
  CCCTCGGGCCGCCTGCCGCCGTCATGAGGCTGCGGGTGCGGCTTCTGAAGCGGACCTGGC
  CGCTGGAGGTGCCCGAGACGGAGCCGACGCTGGGGCATTTGCGCTCGCACCTAGAGCAGT
  CCCTGCTGTGCACCTGGGGGTACAGTTCTAATACCCGATTTACAATTACATTGAACTACA
  AGGATCCCCTCACTGGAGATGAAGAGACCTTGGCTTCATATGGGATTGTTTCTGGGGACT
  TGATATGTTTGATTCTTCAAGATGACATTCCAGCGCCTAATATACCTTCATCCACAGATT
  CAGAGCATTCTTCACTCCAGAATAATGAGCAACCCTCTTTGGCCACCAGCTCCAATCAGA
  CTAGCATACAGGATGAACAACCAAGTGATTCATTCCAAGGACAGGCAGCCCAGTCTTGTG
  TTTGGAATGACGACAGTATGTTATGGCCTATTCAATATTTTGAAGCTGAGTCAATTCAAG
  ATAATGCGCATATGGCAGAGGGCACAGGTTTTTATCCCTCAAAACCCATGCTCTGNAATG
  AATTGGTGGGAACGCCACGCGGCACATTCATTATAGACCCTTGATTAAATCAGCTGACTG
  TCTTGAGCCCATGATGCCCTGGATAGGGTGAACCACCCTCTCATGTTGGAAGTCAGGGTT
  CATATCCTCAGGGCCCCCAAACCAAAGCCCTGGTCATTCCCGAGNAAATGGTAATTGGCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_012179 unedited
  ACCGCGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTAATTAACA
  CTTTTTTTTAATCTGGTAAGAACAGCATCAGAAAACAAACTTCAATCTAGAGGAGAACCA
  AGAGCAGGGAGATTGGCAGCCAACTATTCCCAAGGCCAACCTTGTCACAGAGGAACCTTT
  GGGTCATACCACCCCTAGGGCTATAAATGTATCTCTTAAAAGGTTTCTGGGAGTGCAACT
  CTCAACACCACAATCAGAAAATAACACTCGAGATCAGCACCCCAAGGAGTTGACATCTGT
  AGTTTAAAAACAAAAACAAATGGAGCTCCAGAAATGAAATTACAAATCAATCACATGAAT
  GACAGCCGGCCATCAGTTGGCCGACCCCTGCTGGGTCTAAAGGGAAATCTGTCATTGGGG
  CCGCCTCGCCCTGGCAAGATGGGGTTAGGTCCTGGAAGTGGGCCAACTGGATCAAAGCGT
  GGTCTCAGTGGAGGAAACTGGCTGGGCGTCTCCCCAGGACCAGGAATGAGTGAACTGATT
  GGGTCTCCAACATAGGGAAGTGTTGGTCTTTGGTCATATTCACCCCCGATAATTCCTGGA
  GGAAGGCGGGAGCTAGGAAATGGCCTAGGGTGCAAGGGGTTGGGATAGAATGGAATGGTG
  TGAGTTGACGATGGCAGGAGCATCACAAACCGCCCTTTCGGGGATTCTTTTCTTGTATGT
  GCCTCTCCTGTACGNTCTTTCCATCTGTGTCTTGACTCTGACGTTTGTCTCGAAAATACG
  CAGATATAAAACCTNCACAGGAGTGGGTCATTTGAGCAGTAAAGAGTCCCGACAAACGCA
  GACAAGAAAGACGGACGAACATCAGAGTCGAAGACCGTATTTCAGTCCATGGGAGAACAC
  AACCAATACATTGGTAGTCACGCTGTCGGTAAAACCAAGAGGACACCACTTTCTAAAAGC
  AAAAAGTTGAAATCTGATAGTGGCCCATTCCCTATTTCTTGA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_012179
• Insert Size: 2040 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_012179.3, NP_036311.3
• RefSeq Size: 2153 bp
• RefSeq ORF: 1569 bp
• Locus ID: 25793
• UniProt ID: Q9Y3I1
• Cytogenetics: 22q12.3
• Domains: F-box
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript and it encodes the longer protein (isoform 1).