PAG608 (ZMAT3) (NM_022470) Human Untagged Clone

SKU SC112489

ZMAT3 (untagged)-Human zinc finger, matrin-type 3 (ZMAT3), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: PAG608
• Synonyms: PAG608; WIG-1; WIG1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC112489 sequence for NM_022470 edited (data generated by NextGen Sequencing); ATGATCCTCTTGCAACACGCCGTGCTTCCTCCACCTAAGCAGCCCTCACCCTCGCCTCCT; ATGTCAGTGGCCACCAGGTCTACAGGAACCTTGCAGCTTCCACCACAGAAGCCTTTTGGG; CAGGAGGCTTCCTTGCCTCTTGCAGGGKAAGAAGAGTTATCGAAGGGAGGGGAGCAAGAC; TGTGCCCTGGAGGAGCTATGTAAGCCCCTGTACTGCAAACTCTGCAATGTCACCTTGAAC; TCTGCACAGCAAGCCCAGGCTCATTATCAGGGTAAAAATCATGGTAAGAAACTCCGAAAT; TACTATGCAGCAAATAGCTGTCCTCCTCCTGCTAGAATGAGCAATGTGGTCGAGCCTGCA; GCTACTCCAGTTGTTCCAGTCCCTCCGCAGATGGGCTCCTTTAAGCCAGGAGGCCGAGTG; ATCCTGGCCACGGAGAATGATTACTGTAAGCTCTGTGATGCCTCCTTCAGTTCCCCAGCT; GTGGCTCAGGCTCACTATCAAGGGAAGAATCATGCCAAGAGGCTGCGGCTGGCGGAAGCT; CAGAGTAACTCATTCTCGGAATCCTCAGAGCTGGGTCAACGGCGGGCCAGGAAAGAAGGG; AATGAGTTTAAGATGATGCCTAACAGGAGAAATATGTATACAGTACAGAATAATTCAGCA; GGTCCTTACTTCAATCCCCGCTCTCGGCAGAGAATTCCACGTGATCTGGCCATGTGTGTT; ACTCCAAGTGGCCAGTTTTACTGCTCAATGTGTAATGTTGGAGCTGGCGAAGAGATGGAA; TTCCGGCAGCATTTAGAGAGCAAGCAACATAAGAGCAAGGTGTCTGAACAGCGGTACAGG; AATGAGATGGAGAATCTGGGATATGTATAG; ; Clone variation with respect to NM_022470.3; 148 g=>k
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_022470 unedited; NGTTCAAATTTTGTAATACGACTCACTTATAGGGCGGCCGCGAATTCGCACGAGGCGGCG; GCCGGCGGAGAAGTTGCTCCGAGAAGAGCTGGGTCGAGCTGGGCCGAGCCGGGCGCGCAG; GGCGGGCGTCGCGGGCGTCCCGGGCGGACGCGGCGCGGAGACTGCCGGCGCGTCCCGGGG; GTTCCGATTTGAAGACCTTGCTTCTCATCACCCACTGGATTATGCCCCAGGCTTTCCTAC; CCAATGATCCTCTTGCAACACGCCGTGCTTCCTCCACCTAAGCAGCCCTCACCCTCGCCT; CCTATGTCAGTGGCCACCAGGTCTACAGGAACCTTGCAGCTTCCACCACAGAAGCCTTTT; GGGCAGGAGGCTTCCTTGCCTCTTGCAGGGGAAGAAGAGTTATCGAAGGGAGGGGAGCAA; GACTGTGCCCTGGAGGAGCTATGTAAGCCCCTGTACTGCAAACTCTGCAATGTCACCTTG; AACTCTGCACAGCAAGCCCAGGCTCATTATCAGGGTAAAAATCATGGTAAGAAACTCCGA; AATTACTATGCAGCAAATAGCTGTCCTCCTCCTGCTAGAATGAGCAATGTGGTCGAGCCT; GCAGCTACTCCAGTTGTTCCAGTCCCTCCGCAGATGGGCTCCTTTAAGCCAGGAGGCCNG; AGTGATCCTGGCCACGGAGAATGATTACTGGTAGCTCTGTGATGCCTCCTTCAGTTCCCC; AGCTGTGGCTCANGCTCACTATCAAGGGAAGAATCATGCCAAGAGGCTGCGGCTGGCGGA; AAGCTCAGAGTACTCATTCTCGGAATCCTCANAGCTGGGTCAACGGCGGGCCAGNNAAGA; ANGGNNATGAGT;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_022470 unedited; NTTTACTCTGGACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTT; TTTTTTTTTTTTTTTTTTTTTTGAAACAGAGTCTCGCTTTGTCACCCAAGCTGGAGTGCA; ATGGCGCCAACTCGGGTTATTGGAAGCTCCCCCTCCCGGGTTCACCCCATTTTCCTGCCT; CAACCTCCAAAGAAACTGGGACTACAGGGACCCACCACCACCCCCGGGTAAAGGTTTGGA; TTTTTAATAAAAAAGGGGGTTCACTGGGTTAACCAAGAAGAACTCGACCTCCTGACCTCG; GGAACCCCCTGGTTTGGCCTCCCAAAAGGCTGGGATTACAGGCGTGAGCCACCCCGCCCG; GCCCTATTTTTTGAAAACATATCCCTCTTAAACCCATTGAATATTCAAATATGAGGCTTG; GAAAACCCACAGCACAACTGGGGCATGAAAAAGGGCTTGGTAAACAAACTGATTCAACTA; GGGGGGAAAAAAAAAGAGGGAAAAAAGGGGCAATTATATGTGTGAAATCCACAACTGGAA; AACAAGTTTAACTGGTTGGAAGTATACAAGCCCATTGGGAGTATTTGAATTCAAAAAAAC; TTGCGCTTCAATGGTGGGGAGACCTGATACCAAAAAAAAAATGTCCCGGGAAAGACCCCA; ACAGGTTTTAATAATGGATCCCTACCGACAATGCCTTGAAGTGGGGGGTCTGGTTAAACC; CCTGGAAACTGAAAACTCTGGTGACCTATTTTAACTCTGAACTAAAAAGAAATCCATACA; CATTCTTTTACAGGACCTAAAACCACCACTTGGCAAAGAGAATGGCAGAAAAAAATGCCC; CGGGAAAAACCCTAACACGTTTTATTATGTATTCTACTACAAAGCCTTGAGGGGCCGGTT; CGTTAACACCTGGGAACCTGAAATTTGCCACACTATTTTCCTGGGACTCAAAGAATA;
• Restriction Sites: NotI-NotI
• ACCN: NM_022470
• Insert Size: 2450 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_022470.2, NP_071915.1
• RefSeq Size: 2432 bp
• RefSeq ORF: 870 bp
• Locus ID: 64393
• UniProt ID: Q9HA38
• Cytogenetics: 3q26.32
• Domains: zf-C2H2, ZnF_U1
• Protein Families: Transcription Factors
• Protein Pathways: p53 signaling pathway
• Summary: This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid. [provided by RefSeq, Jul 2008]; Transcript Variant: This variant (1) lacks an alternate exon in the 5' UTR and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The resulting isoform (1) includes one extra residue in the C-terminal region, compared to isoform 2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.