UNC93B (UNC93B1) (NM_030930) Human Untagged Clone

CAT#: SC111446

UNC93B1 (untagged)-Human unc-93 homolog B1 (C. elegans) (UNC93B1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UNC93B
• Synonyms: IIAE1; Unc-93B1; UNC93; UNC93B
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC111446 sequence for NM_030930 edited (data generated by NextGen Sequencing)
  ATGGAGGCGGAGCCGCCGCTCTACCCGATGGCGGGGGCTGCGGGGCCGCAGGGCGACGAG
  GACCTGCTCGGGGTCCCGGACGGGCCCGAGGCCCCGCTGGACGAGCTGGTGGGCGCGTAC
  CCCAACTACAACGAGGAGGAGGAGGAGCGCCGCNNNNNNCGCCGCAAGCGCCTGGGCGTG
  CTCAAGAACGTGCTGGCTGCCAGCGCCGGGGGCATGCTCACCTACGGCGTCTACCTGGGC
  CTCCTGCAGATGCAGCTGATCCTGCACTACGACGAGACCTACCGCGAGGTGAAGTATGGC
  AACATGGGGCTGCCCGACATCGACAGCAAAATGCTGATGGGCATCAACGTGACTCCCATC
  GCCGCCCTGCTCTACACACCTGTGCTCATCAGGTTTTTTGGAACGAAGTGGATGATGTTC
  CTCGCTGTGGGCATCTACGCCCTCTTTGTCTCCACCAACTACTGGGAGCGCTACTACACG
  CTTGTGCCCTCGGCTGTGGCCCTGGGCATGGCCATCGTGCCTCTTTGGGCTTCCATGGGC
  AACTACATCACCAGGATGGCGCAGAAGTACCATGAGTACTCCCACTACAAGGAGCAGGAT
  GGGCAGGGGATGAAGCAGCGGCCTCCGCGGGGCTCCCACGCGCCCTATCTCCTGGTCTTC
  CAAGCCATCTTCTACAGCTTCTTCCATCTGAGCTTCGCCTGCGCCCAGCTGCCCATGATT
  TATTTCCTGAACCACTACCTGTATGACCTGAACCACACGCTGTACAATGTGCAGAGCTGC
  GGCACCAACAGCCACGGGATCCTCAGCGGCTTCAACAAGACGGTTCTGCGGACGCTCCCG
  CGGAGCGGAAACCTCATTGTGGTGGAGAGCGTGCTCATGGCAGTGGCCTTCCTGGCCATG
  CTGCTGGTGCTGGGTTTGTGCGGAGCCGCTTACCGGCCCACGGAGGAGATCGATCTGCGC
  AGCGTGGGCTGGGGCAACATCTTCCAGCTGCCCTTCAAGCACGTGCGTGACTACCGCCTG
  CGCCACCTCGTGCCTTTCTTTATCTACAGCGGCTTCGAGGTGCTCTTTGCCTGCACTGGT
  ATCGCCTTGGGCTATGGCGTGTGCTCGGTGGGGCTGGAGCGGCTGGCTTACCTCCTCGTG
  GCTTACAGCCTGGGCGCCTCAGCCGCCTCACTCCTGGGCCTGCTGGGCCTGTGGCTGCCA
  CGCCCGGTGCCCCTGGTGGCCGGAGCAGGGGTGCACCTGCTGCTCACCTTCATCCTCTTT
  TTCTGGGCCCCTGTGCCTCGGGTCCTGCAACACAGCTGGATCCTCTATGTGGCAGCTGCC
  CTTTGGGGTGTGGGCAGTGCCCTGAACAAGACTGGACTCAGCACACTCCTGGGAATCTTG
  TACGAAGACAAGGAGAGACAGGACTTCATCTTCACCATCTACCACTGGTGGCAGGCTGTG
  GCCATCTTCACCGTGTACCTGGGCTCGAGCCTGCACATGAAGGCTAAGCTGGCGGTGCTG
  CTGGTGACGCTGGTGGCGGCCGCGGTCTCCTACCTGCGGATGGAGCAGAAGCTGCGSCGG
  GGCGTGGCCCCGCGCCAGCCCCGCATCCCGCGGCCCCAGCACAAGGTGCGCGGTTACCGC
  TACTTGGAGGAGGACAACTCGGACGAGAGCGACGCGGAGGGCGAGCATGGGGACGGCGCG
  GAGGAGGAGGCGCCGCCCGCAGGGCCCAGGCCTGGCCCCGAGCCCGCTGGACTCGGCCGC
  CGGCCCTGCCCGTACGAACAGGCGCAGGGGGGAGACGGGCCGGAGGAGCAGTGA
  
  Clone variation with respect to NM_030930.2
  154 t=>n;155 a=>n;156 c=>n;157 t=>n;158 a=>n;159 c=>n;1557 c=>s
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_030930 unedited
  AGAATTTTGTAATACGACTCACTATAGGGGCGGCCGCGATTCGGCACGAGCCGCCGCGAG
  TCCGCAGTAGTTCGGGCCATGGAGGCGGAGCCGCCGCTCTACCCGATGGCGGGGGCTGCG
  GGGCCGCAGGGCGACGAGGACCTGCTCGGGGTCCCGGACGGGCCCGAGGCCCCGCTGGAC
  GAGCTGGTGGGCGCGTACCCCAACTACAACGAGGAGGAGGAGGAGCGCCGCTACTACCGC
  CGCAAGCGCCTGGGCGTGCTCAAGAACGTGCTGGCTGCCAGCGCCGGGGGCATGCTCACC
  TACGGCGTCTACCTGGGCCTCCTGCAGATGCAGCTGATCCTGCACTACGACGAGACCTAC
  CGCGAGGTGAAGTATGGCAACATGGGGCTGCCCGACATCGACAGCAAAATGCTGATGGGC
  ATCAACGTGACTCCCATCGCCGCCCTGCTCTACACACCTGTGCTCATCAGGTTTTTTGGA
  ACGAAGTGGATGATGTTCCTCGCTGTGGGCATCTACGCCCTCTTTGTCTCCACCAACTAC
  TGGGAGCGCTACTACACGCTTGTGCCCTCGGCTGTGGCCCTGGGCATGGCCATCGTGCCT
  CTTTGGGCTTCCATGGGCAACTACATCACCAGGATGGCGNCAGAAGTACCATGAGTACTC
  CCACTACAGGGGAGCANGATGGGCAGGGGGATGAAGCAGCGGCTNNCCGCGGGGCTCCCA
  CGCGCCCTATCTNNCTGGNTCTTCCAAGCCATCTTCTACAGCTTCTTCCATCTGAGCTTT
  CGCTGCGCCAGCTGCCATGAATTTATTTCCTGACCACTACCTGTATGACCCTGACACACC
  TGTACATTGTGCAGAGCTGCGCACACGCNCCACGGATCCTCACGTCCAANAAAAGGGTTT
  TGCGACCTCGGGGGACGACTCCTTTGGGGGGGGGAAGCGTTAAGGGAAAGCCTCGCCCTN
  CGNNNGNGNNNNTTTNTTTGCCAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_030930 unedited
  AGCCAATCCCTGCCCCGCCGCCCCCAATATAGGCANGGATTTTTCTTTTTTTTTTTGACG
  GCCCCCCAATTTTTTTATTGTTCATTTTATGTTCAAAAAGTGGATCTCGGCGGACCCTGG
  GGATCGGAGGGGCAAAGAGCGCTCACACGCGGCCCGGGTCCGCGGCCGAGAGATGAGGGG
  ATCTGGCGCCGGCCGGCCCGCAAGAAGACCCTGACCGCGCTTCTTTTTTCTGGGGCGCGC
  GCTAAGGGCCCGCGGGGCCTAAACTGCATTTTTTAAACCCTGTGCTTGGCCGAGGGGCTC
  CCAAGGTTTCACTTATACTTGCAGGGGGCTGCGGAAGCCCGGCAGCGACCTGGGCTATGG
  GAGGGGCGTACCCAACGTGGGGGAGGGGAGACAGGGGCCTTTAAAAACAGCGTACCACTC
  GCAGGGGGCCCTCCCGACCTCACCCTGGTCACCTGAGGCCCGAGAGGAAGGAGGCTGAGT
  CCGGGGACCACGCGGCACTTCACTGCTCTTACGGTCTGTATCTCCCTTGATTCTGTCTTT
  TATGTAATGGCCGGCGTCCGTATTTCCGGCCTCCGCGTCAAACTTGGGCCTTGGTGGTGG
  ACTAATCTACATTCTGGCCGTCCCCATGATTGACATACGCGTAACTATACCCTCGCAATG
  CCCTCTTCTAACTTACTGAACCATACACACCTATAGACTGTGTCCCCTCTAATCACAACC
  TTGAACCGGGGTCACCACCACAGGAGTAACCTCTGCTCATTTCGAAGTCCAAAAACCCGG
  GTCGCCCACCAAAGTATCCCAGACCCGTAATACTTATTTTTTTTGTCTTTGTCTTTAAAT
  TCGGTCTATTCGTTAATTGATACCTTTTGCCTTCAATTTTTATGTGTTAATCTCCCCCGT
  TTATCTTTTTGCTACTTCACGCGCCCCCCCCCTTCTC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_030930
• Insert Size: 2370 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_030930.2, NP_112192.2
• RefSeq Size: 2334 bp
• RefSeq ORF: 1794 bp
• Locus ID: 81622
• UniProt ID: Q9H1C4
• Cytogenetics: 11q13.2
• Protein Families: Transmembrane
• Gene Summary: This gene encodes a protein that is involved in innate and adaptive immune response by regulating toll-like receptor signaling. The encoded protein traffics nucleotide sensing toll-like receptors to the endolysosome from the endoplasmic reticulum. Deficiency of the encoded protein has been associated with herpes simplex encephalitis. [provided by RefSeq, Feb 2014]