beta Catenin(CTNNB1) (NM_001904) Human Untagged Clone

CAT#: SC107921

CTNNB1 (untagged)-Human catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), transcript variant 1

USD 196.00


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Size
    • 10 ug

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Specifications

Product Data
Product Name beta Catenin(CTNNB1) (NM_001904) Human Untagged Clone
Symbol CTNNB1
Synonyms armadillo; CTNNB; MRD19
Vector pCMV6-XL5
Sequence Data
Fully Sequenced ORF
>OriGene ORF sequence for NM_001904 edited
GCGAATTCGCACGAGGCCTCGTGCCGAATTCGGCACGAGGCGGGAGCGGAGAGCGAGGGG
AGGCGGAGACGGAGGAAGGTCTGAGGAGCAGCTTCAGTCCCCGCCGAGCCGCCACCGCAG
GTCGAGGACGGTCGGACTCCCGCGGCGGGAGGAGCCTGTTCCCCTGAGGGTATTTGAAGT
ATACCATACAACTGTTTTGAAAATCCAGCGTGGACAATGGCTACTCAAGCTGATTTGATG
GAGTTGGACATGGCCATGGAACCAGACAGAAAAGCGGCTGTTAGTCACTGGCAGCAACAG
TCTTACCTGGACTCTGGAATCCATTCTGGTGCCACTACCACAGCTCCTTCTCTGAGTGGT
AAAGGCAATCCTGAGGAAGAGGATGTGGATACCTCCCAAGTCCTGTATGAGTGGGAACAG
GGATTTTCTCAGTCCTTCACTCAAGAACAAGTAGCTGATATTGATGGACAGTATGCAATG
ACTCGAGCTCAGAGGGTACGAGCTGCTATGTTCCCTGAGACATTAGATGAGGGCATGCAG
ATCCCATCTACACAGTTTGATGCTGCTCATCCCACTAATGTCCAGCGTTTGGCTGAACCA
TCACAGATGCTGAAACATGCAGTTGTAAACTTGATTAACTATCAAGATGATGCAGAACTT
GCCACACGTGCAATCCCTGAACTGACAAAACTGCTAAATGACGAGGACCAGGTGGTGGTT
AATAAGGCTGCAGTTATGGTCCATCAGCTTTCTAAAAAGGAAGCTTCCAGACACGCTATC
ATGCGTTCTCCTCAGATGGTGTCTGCTATTGTACGTACCATGCAGAATACAAATGATGTA
GAAACAGCTCGTTGTACCGCTGGGACCTTGCATAACCTTTCCCATCATCGTGAGGGCTTA
CTGGCCATCTTTAAGTCTGGAGGCATTCCTGCCCTGGTGAAAATGCTTGGTTCACCAGTG
GATTCTGTGTTGTTTTATGCCATTACAACTCTCCACAACCTTTTATTACATCAAGAAGGA
GCTAAAATGGCAGTGCGTTTAGCTGGTGGGCTGCAGAAAATGGTTGCCTTGCTCAACAAA
ACAAATGTTAAATTCTTGGCTATTACGACAGACTGCCTTCAAATTTTAGCTTATGGCAAC
CAAGAAAGCAAGCTCATCATACTGGCTAGTGGTGGACCCCAAGCTTTAGTAAATATAATG
AGGACCTATACTTACGAAAAACTACTGTGGACCACAAGCAGAGTGCTGAAGGTGCTATCT
GTCTGCTCTAGTAATAAGCCGGCTATTGTAGAAGCTGGTGGAATGCAAGCTTTAGGACTT
CACCTGACAGATCCAAGTCAACGTCTTGTTCAGAACTGTCTTTGGACTCTCAGGAATCTT
TCAGATGCTGCAACTAAACAGGAAGGGATGGAAGGTCTCCTTGGGACTCTTGTTCAGCTT
CTGGGTTCAGATGATATAAATGTGGTCACCTGTGCAGCTGGAATTCTTTCTAACCTCACT
TGCAATAATTATAAGAACAAGATGATGGTCTGCCAAGTGGGTGGTATAGAGGCTCTTGTG
CGTACTGTCCTTCGGGCTGGTGACAGGGAAGACATCACTGAGCCTGCCATCTGTGCTCTT
CGTCATCTGACCAGCCGACACCAAGAAGCAGAGATGGCCCAGAATGCAGTTCGCCTTCAC
TATGGACTACCAGTTGTGGTTAAGCTCTTACACCCACCATCCCACTGGCCTCTGATAAAG
GCTACTGTTGGATTGATTCGAAATCTTGCCCTTTGTCCCGCAAATCATGCACCTTTGCGT
GAGCAGGGTGCCATTCCACGACTAGTTCAGTTGCTTGTTCGTGCACATCAAGATACCCAG
CGCCGTACGTCCATGGGTGGGACACAGCAGCAATTTGTGGAGGGGGTCCGCATGGAAGAA
ATAGTTGAAGGTTGTACCGGAGCCCTTCACATCCTAGCTCGGGATGTTCACAACCGAATT
GTTATCAGAGGACTAAATACCATTCCATTGTTTGTGCAGCTGCTTTATTCTCCCATTGAA
AACATCCAAAGAGTAGCTGCAGGGGTCCTCTGTGAACTTGCTCAGGACAAGGAAGCTGCA
GAAGCTATTGAAGCTGAGGGAGCCACAGCTCCTCTGACAGAGTTACTTCACTCTAGGAAT
GAAGGTGTGGCGACATATGCAGCTGCTGTTTTGTTCCGAATGTCTGAGGACAAGCCACAA
GATTACAAGAAACGGCTTTCAGTTGAGCTGACCAGCTCTCTCTTCAGAACAGAGCCAATG
GCTTGGAATGAGACTGCTGATCTTGGACTTGATATTGGTGCCCAGGGAGAACCCCTTGGA
TATCGCCAGGATGATCCTAGCTATCGTTCTTTTCACTCTGGTGGATATGGCCAGGATGCC
TTGGGTATGGACCCCATGATGGAACATGAGATGGGTGGCCACCACCCTGGTGCTGACTAT
CCAGTTGATGGGCTGCCAGATCTGGGGCATGCCCAGGACCTCATGGATGGGCTGCCTCCA
GGTGACAGCAATCAGCTGGCCTGGTTTGATACTGACCTGTAAATCATCCTTTAAGTAAGA
AGTTTTAAAAAGCCAGTTTGGGTAAAATACTTTTACTCTGCCTACAGAACTTCAGAAAGA
CTTGGTTGGTAGGGTGGGAGTGGTTTAGGCTATTTGTAAATCTGCCACAAAAACAGGTAT
ATACTTTGAAAGGAGATGTCTTGGAACATTGGAATGTTCTCAGATTTCTGGTTGTTATGT
GATCATGTGTGGAAGTTATTAACTTTAATGTTTTTTGCCACAGCTTTTGCAACTTAATAC
TCAAATGAGTAACATTTGCTGTTTTAAACATTAATAGCAGCCTTTCTCTCTTTATACAGC
TGTAT
5' Read Nucleotide Sequence
>OriGene 5' read for NM_001904 unedited
CGGATTATGAAACCGCACTTACTATAGGGCGGCCGCGCAATTCGCACGAGGCCTCGTGCC
GAATTCGGCACGAGGCGGGAGCGGAGAGCGAGGGGAGGCGGAGACGGAGGAAGGTCTGAG
GAGCAGCTTCAGTCCCCGCCGAGCCGCCACCGCAGGTCGAGGACGGTCGGACTCCCGCGG
CGGGAGGAGCCTGTTCCCCTGAGGGTATTTTTTTTATACCATACAACTGTTTTGAAAATC
CAGCGTGGACAATGGCTACTCAAGCTGATTTGATGGAGTTGGACATGGCCATGGAACCAG
ACAGAAAAGCGGCTGTTAGTCACTGGCAGCAACAGTCTTACCTGGACTCTGGAATCCATT
CTGGTGCCACTACCACAGCTCCTTCTCTGAGTGGTAAAGGCAATCCTGAGGAAGAGGATG
TGGATACCTCCCAAGTCCTGTATGAGTGGGAACAGGGATTTTCTCAGTCCTTCACTCAAG
AACAAGTAGCTGATATTGATGGACAGTATGCAATGACTCGAGCTCAGAGGGTACGAGCTG
CTATGTTCCCTGAGACATTAGATGAGGGCATGCAGATCCCATCTACACAGTTTGATGCTG
CTCATCCCACTAATGTCCAGCGTTTGGCTGAACCATCACAGATGCTGAAACATGCAGTTG
TAAACTTGATTAACTATCAAGATGATGCAGAACTTGCCACACGTGCAATCCCTGAACTGA
CAAAACTGCTAAATGACGAGGACCAGGTGGTGGTTAATAAGGCTGCAGTTATGGTCCATC
AGCTTTCTAAAAGGAAGCTTCCAGACACGCTATCATGCGTNCTCCTCAGATGGTGTCTGC
TATTGTACGTACCATGCCAGATACAAATGATGTAGAAACAGCTCGTTGTACCCGCTGGGA
CCTTGCATNACCTTNTCCCANCATGCGTGAGGGCTTACTGGNCCATTTTTAANTCTGGAA
GCATTCCTGCCCTTTGTTGAAATGCTG
3' Read Nucleotide Sequence
>OriGene 3' read for NM_001904 unedited
CGGCACGCAATCTAGTGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
AAAGAATAAAAAGTTTAATTCTGAACCATTTTTTATAACCGCATTTTCTCTTGAAGCATC
GTATCACAGCAGGTTACAACAACTTTGGGATAAAAGGCAACTGGTAAACTGTCCAAAACA
AGGTTCCAAATAACACCTCTTACTGATTTACCCTACCCATACATATCCCAAATAGTTTTT
GATCAAAAACATGAAATAGATCCACCTGCTTATTTTAAGCATATTAAAAAGGAAACTAAT
TGGACCATTTTCTATTTGTCTATTTTATACAAAAAGGCTACACAATTGTTACACTTTATT
CAAATTACAATTAATTAGAGGGATTATGAATTAGGGTTCTACACCATTACTCAATTCTTA
AAAATTAAAAATTGCTGTAGCAGTATTCACTATAACTTAACACTACGAGAGACTTAAAAA
ACAGTTACTGCAAAAAAAAAAAAAAAAAAAAAAAAGGAGCTTCTTCAAAGCAAGCAAAGT
CAGTACCATTACAGATATTCTTAAAAAAAAAAAAAAAAAAAAATTTAACAAGCAAGGCTA
GGGTTTGATAAATTCCATCTTGAGATCCATTCTTGGGCATTCTTCACTTCTTGAGTCACT
CCCAAAATCCATTTGTATTGTTACTCCTCCACCAAAAAGGACCAGAACAAAAAGTTTACT
TCAATTGTTCCCATAGGAAACTCACCTTGGTTAGTGTGTCAACCACTTTTTGAGAACCAA
CCCCACCCTTGAGCCCTCTTAGNAACTCTACAGGCCAATCACAATGGCAGTTCAGAAAAT
ACAGCTGTATAAAAAAGAAAGCTGCCTTTAATGTTTATAACAGCAGTGTTCTCATTGGAT
TTTAAGTGCAAAGCCGGGCGAAAACCTTAAGTTATAACTTCCACTGATCCCTATCACCGT
ATTGGGACCTTCATGTCCG
Restriction Sites NotI-NotI     
Tag Tag Free
ACCN NM_001904
ORF Size 2346 bp
Insert Size 4000
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reference Data
RefSeq NM_001904.2, NP_001895
RefSeq Size 3697
Locus ID 1499
Cytogenetics 3p22.1
Domains ARM
Protein Families ES Cell Differentiation/IPS, Transcription Factors, Druggable Genome
Protein Pathways Wnt signaling pathway, Focal adhesion, Adherens junction, Tight junction, Leukocyte transendothelial migration, Melanogenesis, Pathogenic Escherichia coli infection, Pathways in cancer, Colorectal cancer, Endometrial cancer, Prostate cancer, Thyroid cancer, Basal cell carcinoma, Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Gene Summary The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein.
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Citations