RANTES(CCL5) (AK092450) Human Untagged Clone

CAT#: SC102926

(untagged)-Human cDNA FLJ35131 fis, clone PLACE6008824

USD 618


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In Stock

Size
    • 10 ug

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Specifications

Product Data
Product Name RANTES(CCL5) (AK092450) Human Untagged Clone
Symbol CCL5
Vector pCMV6-XL5
Sequence Data
Fully Sequenced ORF
>NCBI ORF sequence for AK092450, the custom clone sequence may differ by one or more nucleotides


AAGTACTTTATAGATTCAGAAGTAAATGCTGTCCTGTTCTCCATCAGCTGTTCGTTTGTTACAGATTTTG
TATTTCTTTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCACACAGGCTGGAGTACAGTGGTGCGGTCT
CGGCTCCCTGCAACCTCTGCCTCCCGGGTTCAAGCGATTCTTCTGCCTCAGCCTCCTGAGTAGCTGGGAC
TACAGGCGCGTGCCACCACCCCTGGCTAATTTTTGTATTTTTTTTTCTTTTTTTTTTGAGAAGGAGTCTC
TCTCTGTCACCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCAAGCTGCGCCTCCTGGGTTCAC
GCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGAATTACAGGCGTCCGCCACCGTGCCCGGCTAATTTT
TTTGTATTTTTAGTAGAGATGGGGTTTTGCCATATTGGCCAGGCTGGTCTCGAACTCCTGACCTCAAGTG
ATCCACCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCACCTGGCCAGATCTTTG
TATGTCTTAAGTGTTTCAAAGTTATAAGCATTTTTCTGGGGGGATGTCCATTTTGGAGGGATCCATTTTG
ATCCTTTGTACTCTATAATGTGAACTTTCCCCTGTTCCAACACTTAAAAGAGAATTATTAGCACATAATC
TAAAAGATGGAATTTTTTTTTTTTCTTGAGACAGAGTCTCGCTCTGTCGCTAGGCTGGAGTGCAGTGGCG
CGATCTTGGCTCACTGCAACCTCTGCCTCCTGGGTTTAAGCGATTCTCCTGCCTCAGCCTCTGGAGTAGC
TGGGACTACTCGTGCATGCCACCACGCCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCAT
GTTGGCCAGGATGGTCTCGATCTCTTGACCTCGTGATCCACCTGCCTCGGCCTCCCAAATTGCTGGGATT
ACAGCACTGTGCCCTCCTAGGAAATTATTTTTTAAGTGAAATTTTATTTTTATTTTTTTTAGGATTTTGG
TAGAGAATGAGTAGGCCTACTCATCAATATCAAACAGGACATTTAGTTTCTTTCCTTAGAACAGACATAA
ATTTAATTTCATGGTAATATGATAATAAGAAAATGCTTCTATTTTTCTTTAGCACCTCCATGGTTCTCAT
ATACCCATGTCTGTAAAAAGTGACATGAGAATTTTGTTGGGTTACATTTTATTGTATTTATTAGATTCGC
TTATATAGATGACTTAGGCAGAAATAAAGTCATGTCTTTAGAAGGTGAACAAGCCAACTTGTGATGGCCT
GCCTTTTGCTTTTGGCAGTTGGGATGAGAACAATTGACTCTCCCATTGGTTGTTAGATAGTTGAAATGGT
GCGTTGGTGGTCATACTTAGTGTTCTAGGCTGTGAAATCATGGAGTTCTTCCACTTCCAAGAATGACTCA
TTTGCTGTTGGATTCTAGTACAGAATTTAGCAGCCTGATGTGTCCCCAAACTGATTTAATTTCTACTGAA
GTGCCCTTGTGTACATTTGTTTTGTAATTTACCAAAGTACTACCTGAGTGTATAATGACTCCTGCAGTGA
GTTAATGTAATTGCTGCTTTGACCATTGTTTTAAATCTGTGTACTAGAGTAACTGTGAGCAGAATGAAAT
CACATTATCTCAGTGTTCAAAATATCATTCTAATAAAGTACATGCATTAAACAATTTT


5' Read Nucleotide Sequence
>OriGene 5' read for AK092450 unedited
GATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGTATAGGCATAG
TGTAAATTACATTAATGTAGTAAAACATCAATTGTGGTTCGGTTTGTCTTTCATTTATGT
GTAGTATAGAAATCACCTTTCTAATATGTGTTGCCAAACTATTTGCCACCATCTATTTGG
TGAAATATTCATTGTCATTGTGATTTTCCACAAGTATAAGTTCTTAAGTACTTTATAGAT
TCAGAAGTAAATGCTGTCCTGTTCTCCATCAGCTGTTCGTTTGTTACAGATTTTGTATTT
CTTTTTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCACACAGGCTGGAGTACAGTGGT
GCGGTCTCGGCTCCCTGCAACCTCTGCCTCCCGGGTTCAAGCGATTCTTCTGCCTCGGCC
TCCTGAGTAGCTGGGACTGCAGGCGCGTGCCACCACCCCTGGCTAATTTTTGGATTTTTT
TTTCTTTTTTTTTTTGAGAAGGAGTCTCTCTCTGTCACCCAGGCTGGAGTGCAGTGGCAC
GATCTCGGCTCACTGCAAGCTGCGCCTCCTGGGTTCACGCCATTCTCCTGCCTCAGCCTC
CCGAGTAGCTGGAATTACAGGCGTCCGCCACCGTGCCCGGCTAATTTTTTTGTATTTTTA
GTAGAGATGGGGTTTTGCCATATTGGCCAGGCTGGTCTCGAACTCCTGACCTCAAGTGAT
CCACCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCACCTGGCCA
GATCTTTGTATGTCTTAAGTGNTTCAAAGTTATAAGCATNTTTTCTGGGGGGGATGTCCA
TTNNNTGGAGGGATCCCATTNTGATCCCTTTGNNACTCTATATGNGAAACTTTNCCCTGT
TNNCACACTCANNAGAGAAT
3' Read Nucleotide Sequence
>OriGene 3' read for AK092450 unedited
TAAATCTATGNNACCGCGGCCGCAATCTANGATCGAGTTTTTTTTTTTTTTTTTTGTTTA
ATGCATGTACTTTATTAGAATGATATTTTGAACACTGGAGAAATGTGATTTCATTCTGCT
CACAGTTACTCTAGTACACAGATTTAAAACAATGGTCAAAGCAGCAATTACATTAACTCA
CTGCAGGAGTCATTATACACTCAGGTAGTACTTTGGTAAATTACAAAACAAATGTACACA
AGGGCACTTCAGTAGAAATTAAATCAGTTTGGGGACACATCAGGCTGCTAAATTCTGTAC
TAGAATCCAACAGCAAATGAGTCATTCTTGGAAGTGGAAGAACTCCATGATTTCACAGCC
TAGAACACTAAGTATGACCACCAACGCACCATTTCAACTATCTAACAACCAATGGGAGAG
TCAATTGTTCTCATCCCAACTGCCAAAAGCAAAAGGCAGGCCATCACAAGTTGGCTTGTT
CACCTTCTAAAGACATGACTTTATTTCTGCCTAAGTCATCTATATAAGCGAATCTAATAA
ATACAATAAAATGTAACCCAACAAAATTCTCATGTCACTTTTTACAGACATGGGTATATG
AGAACCATGGAGGTGCTAAAGAAAAAAGAAGCATTTTCTTATTATCATATTACCATGAAA
TTAAATTTATGTCTGGTCTAAGGAAAGAAACTAAATGTCCTGTTTGATATTGATGAGTAA
GCCTACTCATTCTCTACCAAAATCTAAAAAAAATAAAAATAAAATTTCACTTTAAAAAAT
AATTTNCCTAGAAGGCACAGTGCTGTTATTCCCACAATTTTGGGAGGCGAGGCAAGTGGG
TCCACCCAGTCAAGAGATCGGGAACCTTCCTGCCCAATATGTGGAAACCCTGTCCTTCTA
AAAATCCAAAAATTACCCGGCGGGTTGGCATGCCCCAATAT
Restriction Sites NotI-NotI     
Tag Tag Free
ACCN AK092450
ORF Size 1738 bp
Insert Size 2000
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reference Data
RefSeq Size 1738
RefSeq ORF 1738
Locus ID 6352
Cytogenetics 17q12
Protein Families Secreted Protein, Transmembrane, Druggable Genome
Protein Pathways Cytokine-cytokine receptor interaction, Chemokine signaling pathway, Toll-like receptor signaling pathway, NOD-like receptor signaling pathway, Cytosolic DNA-sensing pathway, Prion diseases, Epithelial cell signaling in Helicobacter pylori infection
Gene Summary This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013].
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