Cipc (NM_001289432) Mouse Untagged Clone
CAT#: MC227134
Cipc (untagged) - Mouse CLOCK interacting protein, circadian (Cipc), transcript variant 5
"NM_001289432" in other vectors (1)
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Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Symbol | Cipc |
Synonyms | 2310044G17Rik; AI842544; AI853744; Kiaa1737; mKIAA1737 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC227134 representing NM_001289432
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGTCAGAGGACATGCTGAGCGCCTTGGGCTGCAAGAGAGAAGACAAGCGGAGGCAGCCCTCCAAAG CTGCGGACACTGCCCTCCCCACGCTGCCCCCTATGGTCGTCATGAAGAGCGTGCTGGTCAAGCAGGGCAG CAGCTCCTCCCAGCTTCAGTCCTGGACTGTCCAGCCCTCCTTTGAAGTGATCTCAGCGCAGCCACAGCTC TTTGTCCTTCATCCACCTGTGCCATCTCCTGTCAGCTCATGCCAGACTGGTGAGAAAAAGTCAGAATCCA GAAACTACTTGCCCATTCTAAATTCTTATACCAAAATAGCCCCCCACCCAGGCAAGAGGGGCCTCAATTC AGAAGACAGAGGAACAAGTGGGGTATCGAAGAAACTCTGCACGGAGAGACCGGGGCCAAGCCTGTCTTCC AGTGAGCCAGCCAAGACTGGCCGAGTATTATCCAGTCCTTCCACTCCAGCCCCACCCAGCTCCAAACTCA CTGAGGACTCCACTCTGCAAGGAGTTCCCTCCCTTGGGGCTGGCGGAAGTCCACAGACTCTTCAGCCTGT GTCCAGCAGCCATGTGGCTAAAGCTCCCAGTCTGACTTTGGCTTCGCCCGCCAGCCCTGTGTGTGCGTCA GACAGCACTCTGCATGGCCTAGAGAGCAGCTCCCCTCTCTCCCCACTGTCAGCCAGTTACACTTCACCTC TGTGGGCTGCGGAGCACCTCTGCCGCAGCCCAGACATCTTCTCCGAGCAGAGGCAGAACAAGCATAGGCG CTTTCAGAATACCTTAGTGGTCCTCCACAAGTCTGGTTTGCTGGAGATCACTCTGAAAACCAAGGAGTTG ATTCGTCAGAACCAAGCAACTCAGGCAGAGCTGGACCAGCTGAAGGAGCAAACCCAGATGTTTATAGAGG CCACCAAGAGCAGGGCTCCTCAGGCATGGGCCAAGTTGCAGGCATCACTAACATCTGGGTCCAGTCATTC AGGCAGTGACCTAGACACGTTGTCTGATCACCCAGACGTATAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001289432 |
Insert Size | 1023 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | Clone contains native stop codon, and expresses the complete ORF without any c-terminal tag. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001289432.1, NP_001276361.1 |
RefSeq Size | 4217 bp |
RefSeq ORF | 1023 bp |
Locus ID | 217732 |
Cytogenetics | 12 D2 |
Gene Summary | Transcriptional repressor which may act as a negative-feedback regulator of CLOCK-ARNTL/BMAL1 transcriptional activity in the circadian-clock mechanism. May stimulate ARNTL/BMAL1-dependent phosphorylation of CLOCK (PubMed:17310242, PubMed:19414601). However, the physiogical relevance of these observations is unsure, since experiments in knockout mice showed that CIPC is not critially required for basic circadian clock (PubMed:25862660).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (5) includes an additional internal exon and it thus differs in its 5' UTR and uses a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) is shorter at the N-terminus, compared to isoform a. Variants 2, 4 and 5 all encode isoform b. |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MR229345 | Cipc (myc-DDK-tagged) - Mouse CLOCK interacting protein, circadian (Cipc), transcript variant 5 |
USD 503.00 |
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