Plxna3 (NM_008883) Mouse Untagged Clone

CAT#: MC224994

Plxna3 (untagged) - Mouse plexin A3 (Plxna3), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Plxna3
• Synonyms: mKIAA4078; PlexA3; Plxa3; Plxn3; Plxn4; SEX
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC224994 representing NM_008883
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCCCACTGTCTGCCTTCTCCCATTGCTATTCTTCACCATAGGAGGGTGCCTGGGTAGCAGCAGGCCAT
  TTCGTACCTTTGTGGTAACAGATACCACTCTGACTCACCTGGCTGTGCACCGAGTGACTGGGGAGGTGTT
  TGTAGGTGCCGTGAATCGAGTTTTCAAGCTGGCTCCAAACCTAACTGAGCTACGGGCCCATGTCACAGGG
  CCCATTGAGGACAATGCTCGCTGCTACCCACCTCCTAGCATGCGTGTGTGCTCCCACCGCCTGGTGCCTG
  TGGACAATGTGAACAAGCTGCTCCTCATAGACTATGCAGCCCGTCGTTTGGTAGCTTGTGGCAGCATCTG
  GCAGGGCATCTGCCAGTTCCTGCGTCTGGATGACCTCTTCAAGTTGGGTGAGCCCCACCATCGCAAGGAG
  CACTATCTGTCAGGGGCCCAGGAGCCTGATTCCATGGCTGGCGTCATTGTTGAACAGGTCCAGGGGCCTA
  GCAAGTTGTTTGTGGGCACCGCTGTTGATGGCAAGTCTGAGTACTTTCCCACCTTGAGTTCCCGTAAGCT
  CATCGACGATGAGGACAGTGGAGATATGTTCAGTCTGGTGTACCAGGATGAGTTTGTCTCTTCTCAGATC
  AAGATCCCTTCAGACACATTGTCCTTGTACCCTGCCTTTGACATCTACTACATATATGGCTTTGTCAGTG
  CCTCCTTCGTGTACTTCTTAACGTTGCAGCTGGACACCCAGCAGACGCTGTTGGATACAGCAGGCGAGAA
  ATTCTTCACATCCAAGATCGTGCGCATGTGTGCAGGGGACTCAGAGTTCTACTCTTATGTAGAGTTCCCT
  ATTGGCTGCTCCTGGCGTGGTGTGGAGTACCGCTTGGTGCAGAGTGCCCATCTGGCCAAGCCAGGCCTGC
  TATTGGCCCAGGCTCTGGGTGTGCCAGCCGACGAGGATGTCCTCTTCACCATCTTCTCTCAGGGCCAGAA
  GAACAGAGCCAACCCACCTCGGCAGACCATCCTTTGCCTTTTCACCCTCAGCAGCATTAATGCCCACATC
  CGGCGCCGAATCCAATCGTGCTACCGTGGAGAGGGCACGCTGGCCCTACCCTGGCTACTGAATAAGGAGC
  TGCCCTGCATCAACACCCCTCTGCAGATCAATGGAAACTTCTGTGGGTTAGTGTTGAATCAACCATTGGG
  TGGCCTACACGTGATTGAGGGGCTACCCTTGCTGGCTGACAGCACTGATGGCATGGCCAGTGTGGCTGCC
  TACACCTACCACCAGCATTCTGTGGTTTTCATCGGTACACGCAGCGGTAATTTGAAGAAGGTGCGGGTCG
  ATGGCTCTCAGGATGCCCAGCTATATGAAACGGTCTCTGTGGTGCAGGGCAGCCCCATACTTCGAGACCT
  GCTCTTCAGCCCTGACCACCGACACATCTACCTCCTGAGTGAGAAGCAGGTGAGCCAACTCCCGGTGGAG
  ACCTGTGAGCAGTATCTGAGCTGTGCTGCATGCCTGGGCTCAGGGGACCCACACTGTGGTTGGTGTGTGC
  TACAGCACAGGTGCTGCCGTGAAGGGGCCTGTCCAGGTGCCTCTGCCCCACATGGCTTTGCAGAAGAGCT
  GAGCAAATGTATACAGGTGCGGGTCCGTCCCAATAATGTGTCAGTGACATCCTCTGGGGTGCAGCTGACC
  GTAGCCATGCGCAACGTGCCAGACCTCAGTGTGGGTGTGAGCTGTTCCTTTGAGGAGGTGACTGAAAGTG
  AGGCTATTCTGCTGCCCTCTGGAGAGTTACGATGTCCTTCACCATCCCTTCAGGAGCTCCAGACACTTAC
  CAGAGGGCATGGGGCCACTCATACTGTGCGGCTTCAGCTGCTCTCCATGGAGACTGGTGTGAGGTTTGCT
  GGGGTTGACTTTGTCTTCTACAACTGCAGTGCCCTCCAGTCGTGTATGTCCTGTGTTGGCAGCCCTTACC
  CCTGCCACTGGTGTAAGTACCGTCATGTGTGTACCAGCCACCCACACGAGTGCTCTTTCCAGGAGGGCAG
  GGTCCACAGCCCTGAGGGCTGCCCTGAGATCCTGCCTCAAGGGGACCTCTTGATTCCTGTGGGTGTCATG
  CAGCCTCTAACTCTGCGGGCTAAGAACCTGCCACAGCCTCAGTCCGGACAGAAGAATTATGAATGCGTGG
  TCCGTGTACAGGGACGGCAACATCGGGTACCTGCAGTGCGCTTTAACAGCAGCAGTGTGCAGTGCCAGAA
  TGCCTCGTACTTCTATGAAGGTGATGAGTTTGGTGACACCGAACTGGACTTCTCTGTGGTTTGGGATGGA
  GATTTCCCCATTGATAAGCCTCCTAGCTTCCGAGCCCTTCTTTACAAGTGCTGGGCTCAGCGGCCTAGCT
  GTGGCCTCTGCCTCAAGGCTGATCCCCGATTCAACTGTGGCTGGTGCATCTCAGAGCACAGGTGCCAGCT
  GAGGGCTCACTGCCCAGCTCCCAAAAGTAACTGGATGCACCCAAGCCAGAAGGGTGCCCGATGCAGCCAT
  CCCCGAATCACCCAGATTCATCCACTTACAGGACCCAAGGAGGGTGGCACCCGGGTCACCATTGTGGGTG
  AGAACCTGGGCCTCACTTCCCGTGAGGTTGGCCTTCGAGTAGCTGGTGTACGTTGCAACTCCATTCCCAC
  CGAATATGTCAGTGCTGAAAGGATCGTATGTGAGATGGAGGAATCGCTGGTGCCCAGCCCACCACCTGGG
  CCTGCTGAGCTCTGTGTAGGGGATTGTTCTGCTGACTTCCGCACACAGTCCCAGCAACTCTACAGCTTTG
  TGACCCCTACATTTGACCGTGTGAGTCCCTCTCGGGGCCCAGCTTCTGGAGGCACTCGGCTTACCATCTC
  TGGAATTTCTCTGGATGCCGGCAGCAGGGTCACAGTGATTATAAGAGATGGCGAGTGCCAGTTTGTGAGG
  AGAGATGCCGAGGCAATCGTGTGTATCTCACCTGTCTCCACCCTGGGCCCCAGTCAGAGCCCTATCACCC
  TTGCCATCGATCATGCCAACATCTCCAACACTGGAGTCATCTATACCTACACCCAGGACCCTACGGTCAC
  ACACCTTGAGCCCACCTGGAGCATCATCAATGGAAGCACCTCCATCACTGTGAGTGGAACCCATCTGCTG
  ACAGTTCAAGAACCCCGTGTACGAGCCAAGTACCGTGGTATTGAGACCACTAACACATGCCAGGTGATCA
  ACGACACTGCAATGCTATGTAAGGCCCCTGGCATCTTCCTTGGGCACCCTCAGCCTCGGGCCCAAGGCGA
  GCACCCTGACGAGTTTGGCTTCTTGCTGGACCACGTGCAGGCAGCCCGCTCCCTCAACCGTTCTTCCTTC
  ACCTACTACCCTGATCCCAGCTTTGAACCACTTGGGCCCTCTGGTGTGCTAGATGTCAAACCTGGTTCAC
  ATGTTGTATTGAAGGGCAAGAACCTGATCCCTGCTGCAGCTGGCAGCTCCCGCCTCAACTACACAGTGTT
  GATTGGAGGACAGCCATGTGCACTAACTGTCTCAGATACTCAACTTCTGTGTGATTCCCCAAGCCAGACA
  GGCCGGCAGCCTGTTATGGTGCTGGTGGGTGGCCTGGAGTTCTGGTTGGGCACGCTGCACATCACTGCTG
  ATCGGGCACTGACCTTACCAGCTATGGTGGGGCTAGCAGCAGGGGGCGGGCTCTTGCTGCTGGCCATCAC
  TGTTGTGCTGGTCGCCTACAAGCGTAAGACTCAGGATGCAGACCGCACACTTAAGCGGCTTCAGCTACAA
  ATGGACAACCTGGAGTCTCGTGTGGCCTTGGAGTGCAAGGAAGCCTTTGCTGAGCTGCAGACTGATATCA
  ATGAACTGACAAACCACATGGATGGTGTCCAGATCCCCTTCTTGGACTACCGGACCTATGCTGTGCGCGT
  GCTTTTCCCTGGCATCGAGGCTCACCCAGTGCTCAAGGAGCTGGATACTCCCCCCAATGTGGAGAAGGCC
  CTGCGTCTATTTGGACAGTTGCTGCACAGCCGTGCCTTCCTGCTCACCTTTATCCACACTTTGGAGGCCC
  AGAGTAGTTTCTCCATGCGTGACCGTGGTACTGTGGCCTCACTCACCATGGTGGCCCTGCAGAGCCGGCT
  TGACTATGCCACTGGGCTGCTCAAGCAACTGCTGGCTGACCTCATAGAGAAAAACCTTGAGAGCAAGAAC
  CACCCAAAGCTGCTATTGCGCAGGACAGAGTCGGTGGCTGAGAAGATGCTCACCAACTGGTTCACATTCC
  TGCTGCATAAGTTCCTGAAGGAGTGCGCCGGGGAGCCACTCTTCCTGCTGTACTGCGCCATCAAGCAGCA
  GATGGAGAAAGGTCCTATTGATGCCATAACAGGCGAGGCCCGCTACTCCTTAAGTGAGGACAAGCTCATC
  CGGCAGCAGATCGACTATAAGACCCTGACTCTGCATTGTGTGTGCCCGGAGAGCGAGGGCAGTGCCCAGG
  TCCCTGTGAAGGTTCTTAACTGTGATAGCATCACCCAGGCCAAAGACAAGCTGTTGGATACTGTGTACAA
  GGGTATTCCATACTCTCAGCGCCCCAAAGCTGAGGACATGGATTTGGAATGGCGCCAGGGCCGCATGGCC
  CGAATCATCCTCCAAGATGAGGACATCACTACAAAGATTGAGTGTGACTGGAAGAGGGTCAACTCATTGG
  CCCACTACCAGGTGACTGATGGTTCTTTAGTAGCACTGGTGCCCAAACAAGTGTCTGCCTATAACATGGC
  CAACTCGTTCACCTTCACCCGGTCACTTAGTCGCTACGAGAGCTTGCTCCGTGCTGCCAGCAGCCCGGAT
  AGCCTCCGTTCCCGAGCACCTATGCTCACGCCTGACCAGGAGGCAGGTACCAAGCTGTGGCACCTGGTGA
  GGAACCACGACCACACTGATCACCGAGAAGGAGACCGCGGCAGCAAGATGGTCTCAGAAATATATCTCAC
  AAGGCTGCTGGCCACCAAGGGCACGTTGCAGAAGTTTGTAGATGACTTGTTTGAAACTGTGTTCAGTACA
  GCCCACCGGGGCTCAGCCTTACCCTTGGCCATCAAGTACATGTTTGACTTCCTGGATGAACAGGCTGACC
  AGCGCCAGATCAGTGACCCTGATGTGCGTCACACCTGGAAGAGCAACTGCTTACCTCTGCGTTTCTGGGT
  GAATGTGATCAAGAATCCGCAATTTGTGTTTGACATCCATAAGAATAGCATCACAGACGCCTGTTTGTCA
  GTGGTGGCCCAGACCTTCATGGACTCCTGTTCTACATCAGAGCACCGCCTGGGCAAGGACTCACCTTCCA
  ACAAGCTCCTCTATGCCAAGGATATTCCCAATTACAAGAGCTGGGTGGAGAGGTACTATCGAGATATCGC
  AAAGATGGCATCCATCAGTGACCAGGACATGGACGCCTACTTAGTGGAGCAGTCCCGCCTCCATGCTAAT
  GACTTCAATGTCCTAAGTGCACTCAGCGAGCTCTACTTCTATGTCACCAAGTACCGTCAGGAGATCCTCA
  CCTCGCTGGACCGAGATGCCTCTTGTCGGAAGCACAAGCTTCGACAGAAGCTGGAGCAGATCATCACCCT
  GGTGTCCAGCAGCAGCTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_008883
• Insert Size: 5619 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_008883.2, NP_032909.2
• RefSeq Size: 6964 bp
• RefSeq ORF: 5619 bp
• Locus ID: 18846
• UniProt ID: P70208
• Cytogenetics: X 38.0 cM
• Gene Summary: Coreceptor for SEMA3A and SEMA3F. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Regulates the migration of sympathetic neurons, but not of neural crest precursors. Required for normal dendrite spine morphology in pyramidal neurons. May play a role in regulating semaphorin-mediated programmed cell death in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.[UniProtKB/Swiss-Prot Function]