Drp2 (NM_010078) Mouse Untagged Clone

CAT#: MC222826

Drp2 (untagged) - Mouse dystrophin related protein 2 (Drp2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Drp2
• Synonyms: AW495265; DRP-2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC222826 representing NM_010078
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCAACCTTTGGTCATGCAGGGATGCCCTTACACCCTCCCACGATGTCATGAGTGGCATGCTGCTGACC
  GGTTTCATCACAGCAGCAGCCTCCGAAACACCTGTCCCCAGCCTCAGGTTAGAGCTGCGGTCACCATCCC
  TGCTCCACCTTGGGATGGTGCCGGGGATCCCTGCCTAAGTCCAAAGCTCTTGAACGGGACTGTTGGAGCC
  ACCGGGCCCCTGGAGCCATCAGCCATGAATCTGTGTTGGAATGAAATAAAAAAGAAGTCTCACAACCTCC
  GCGCTCGCCTAGAGGCCTTCTCAGACCTCAGTGGAAAACTTCAGCTCCCGCTCCGAGAGATTATTGACTG
  GCTCAGCCAAAAGGATGAGGAGTTGTCAGCTCAGCTCCCCTTGCAAGGGGATGTGGCCCTGGTACAACAG
  GAGAAGGAGACACATGCAGCCTTCATGGAAGAAGTCAAGTCTAAGGGCCCCTACATCTCCTCTGTGCTTG
  AATCCGCCCAGGCTTTTCTGTCCCAGCATCCATTTGAAGAATTAGAGGAGTCTCAATCTGAGAGTAAAGA
  TACCTCCCCCAGACAGCGGATTCAAAACCTTAGTCGCTTTGTATGGAAGCAGGCAACAGTGGCCAGTGAG
  CTGTGGGAGAAGCTGACAGCCCGCTGTGTAGATCAGCATCGCCACATTGAGCATACTCTGGAACATCTAT
  TGGAGATCCAAGGGGCAATGGAGGAATTGAGCAGTACTTTGACCCAAGCAGAGGGAGTCCGAGCCACGTG
  GGAGCCCATAGGAGATCTCTTTATTGATTCCCTCCCAGAGCATATCCAAGCCATCAAGCTATTCAAAGAA
  GAATTCTCTCCTGTGAAAGATGGGGTGAAGTTAGTGAATGATCTGGCCCACCAGCTTGCCATCTCTGATG
  TGCACTTGTCAATGGAGAATTCCAGGGCTCTGGAACAGATCAACATCCGGTGGAAACAGCTCCAGGTGTC
  AGTGGCTGAGAGGCTTAAGCAACTCCAGGATGCCCACCGGGACTTTGGGCCTGGGTCACAGCACTTCCTC
  TCCACTTCTGTCCAAGTTCCCTGGGAAAGAGCAATTTCTCCCAATAAAGTCCCCTACTACATCAACCACC
  AGGCTCAGACCACATGCTGGGACCATCCTAAGATGACTGAGTTATACCAAACCCTAGCCGATCTGAACAA
  CATTAAGTTCTCAGCTTACCGCACTGCCATGAAGCTCCGCAGAGTCCAGAAGGCCCTGCGCCTGGATCTG
  GTAACTTTAACTACAGCTCTGGAGATCTTCAATGAGCATGACTTGCAGGCCAGTGAACATGTGATGGATG
  TGGTGGAGGTCATTCACTGCTTGACTGCCTTGTATGAACGACTGGAGGAGGAAAGAGGCATCCTGGTCAA
  TGTGCCACTGTGTGTAGACATGAGCCTCAACTGGCTCCTCAATGTTTTTGATAGTGGTCGCAGTGGAAAG
  ATGCGAGCATTGTCCTTTAAGACTGGCATCGCATGCCTGTGTGGCACGGAAGTGAAAGAAAAACTTCAGT
  ATCTCTTCAGCCAAGTAGCCAATTCAGGCAGCCAGTGTGATCAACGCCATCTCGGTGCCCTGCTTCATGA
  AGCCATTCAAGTGCCCCGTCAGCTGGGTGAAGTGGCAGCATTTGGGGGCAGCAATGTGGAGCCCAGTGTC
  CGTAGCTGCTTTCGCTTTAGCACTGGCAAGCCAGTCATTGAAGCTTCCCAATTCCTGGAGTGGGTCAACT
  TGGAGCCCCAGTCTATGGTGTGGCTGGCTGTTCTGCATCGGGTCACCATCGCTGAGCAAGTGAAGCATCA
  AACCAAGTGCTCTATCTGTAGACAGTGCCCCATCAAAGGGTTCAGGTACCGGAGTCTGAAACAGTTTAAC
  GTGGATATCTGCCAGACCTGCTTCTTGACCGGCAGGGCCAGCAAAGGCAACAAGCTCCACTATCCCATCA
  TGGAGTATTACACACCGACCACATCTAGTGAAAACATGAGGGACTTTGCCACAACCTTAAAGAATAAATT
  CCGCTCCAAGCAGTATTTCAGCAAACACCCTCAGCGAGGTTATCTGCCCGTGCAGTCAGTTCTGGAGAGC
  GACTGCAGTGAGACACCTGCTTCTTCCCCGATGTTGCCACACGCTGACACACACTCTCGAATTGAACATT
  TTGCCAGCAGGCTTGCTGAGATGGAAAGTCAAAATTGTTCCTTTTTTAATGACAGCCTGTCCCCGGATGA
  TAGCATCGATGAGGACCAGTACCTGTTGCGGCACTCCAGCCCCATCACAGACCGAGAGCCGGCCTTTGGA
  CAGCAGGCTCCATGCAGCATGGCCACAGAAAGCAAGGGGGAGCTAGAGAAGATCTTGGCCCATTTAGAAG
  ATGAGAACCGGATTCTCCAGGGAGAGCTGAGGCGCCTGAAATGGCAGCACGAGGAGGCAGCCGAGGCACC
  TACCCTGGTTGAGGGCTCTGCTGAAGCCACCCCAGACCACCGCAATGAAGAACTTCTGGCTGAAGCCAGG
  ATCCTGCGGCAGCACAAAAGCCGCCTGGAGACGCGCATGCAGATCCTTGAAGACCACAACAAGCAGCTCG
  AGTCTCAGCTGCAACGCCTGAGGGAGCTGCTCCTGCAGCCACCCAGTGAATCAGATGGCAATGGCTCTGC
  AGGCTCCTCCCTAGCTTCCTCTCCACGCCAGTCAGAAGGCAGTCATCCCCGGGAGAAGGGACAGACTACT
  CCAGACACTGAGGTTGCAGATGATGTGGGGTCAAAGAGTCAGGATGTCAGCCTATGCTTAGAAGACATCA
  TGGAGAAGCTCCGCCATGCCTTCCCCAGTGTGCGAAGCTCTGATGTGACTGCAAACACTCTGCTGGCCTC
  TTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_010078
• Insert Size: 2874 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_010078.3, NP_034208.2
• RefSeq Size: 6983 bp
• RefSeq ORF: 2874 bp
• Locus ID: 13497
• UniProt ID: Q05AA6
• Cytogenetics: X E3
• Gene Summary: Required for normal myelination and for normal organization of the cytoplasm and the formation of Cajal bands in myelinating Schwann cells (PubMed:22764250). Required for normal PRX location at appositions between the abaxonal surface of the myelin sheath and the Schwann cell plasma membrane (PubMed:22764250). Possibly involved in membrane-cytoskeleton interactions of the central nervous system.[UniProtKB/Swiss-Prot Function]