Cc2d1a (NM_145970) Mouse Untagged Clone

CAT#: MC222753

Cc2d1a (untagged) - Mouse coiled-coil and C2 domain containing 1A (Cc2d1a), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Cc2d1a
• Synonyms: BC016188; Freud-1; Tape
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC222753 representing NM_145970
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCACAAGAGGAATGGACCCCAGGCACCCCCGGGCCGAGGTGCTGTCACTGCCCGCCAGCTTGGTCTGC
  TGGTTGACTTCTCCCCAGACGGCCTGATGATCCCCGAGGATGGGATTAATGAGGAGGAGCTGGAGGCTGA
  ATTCCTGGCTTTGGTGGGGGGTCAGCCCCAGGCCCTAGAGAAACTGAAAGGCCAAGGTCCCCTGCCAATG
  GAAGCCATTGAGAAGATGGCCCGGCTCTGCATGAGAGACCTGGATGAGGACGAGGAGGGGACAGACGAGG
  ATGATGTGGAGGCTGATGAGGACCTGCTGGCAGAGCTAAATGAGGTCCTTGGAGAAGAACAGAAGGCTGT
  GGAGCCCCTGATGCCTGTGGCCCAGCCGAAGCCTTCAGGCCCCAATCCAGGAGTAGAGGCCACGCTGCAG
  GAGAGGCTAACCCTCTACCAGTCTGCACTGGAGAGTGCCAGGCAAGCTGGGGACAGTGCCAAGATGCGAC
  GCTATGACCGGGGGCTCAAGACGCTGGAAAACCTGCTGGTCTCTGCAAAGAAGGGCAACATCATCAATGA
  AGCAGACATTCCACCACCTGTGGCATCGGGGAAGGGAGCAGCAGCTGGGCACAGCCACACCCAAGCTACT
  TCCCAGTTGGCTTCTGTAAGCCCGCCAGCCCCAGAGTCCAGCGGCACCTTGGAGGCCCCATCTACCACTA
  CACCCACCTCTGCTAAGCCCCAGCTACCCCCAGATCCCTGCAGCCCCCTAGCCCGGTTGCAGAGCCTCCA
  GCACGAGTACAAACTGGCTGCCCTTCGTGCCAAGCATCAGGATGACACTGCTACAGCCACCAGACACTTG
  AGAATAGCTAAGAGCTTTGACCCTGTCTTGGAGGCCCTGAGCCGTGGGGAACTGGTGGACCTGTCCCGCC
  TGCCCCCTCCCCCTGACCAGCTGTCCCCAGAGCCCCCCTTGCCAGCTGCCCAACCTTTGACCTCTGCCTC
  AACACTCACCAGGCCAGAGGTTCCCCAACCCCCGAGGAACCTCCTGGAGGCTCTGGAACAGCGAATGGAG
  CGGTACCATGTGGCTGCAGCCCAGGCCAAGGCCAAGGGTGACCAGCGGAAGGCACGCATGCATGAACGAA
  TTGTCAAGCAATACCAAGACGCCATTCGTGCCCACAAGGCAGGCCGAGCTGTGGATGTGGCGGAGCTGCC
  AGTGCCCCCAGGCTTCCCCCCAATGCAGGGTTTGGAGTCTGCAGAGCCCTCTCAACAGAGCCTAGTGGGT
  GTCCTGGAAACTGCCATGAGGCTTGCCAACCACGACGAAGGCTCGGATGACGAAGAGGAGGAGACTCCTA
  AGAAGCAGAATACCCCTGCTGCCTCCACAACCCAGCTGAAGTCCTCGCCCTCCAAAGCACCTCCATCAGG
  ACCAGCCCCAGCCGGCAAAGCTGCCCCCAAGGGCACATCCAACAGAGCCCAGCAGCAGCTGGCCTTCCTG
  GAGGGCCGTAAGAAGCAGCTCCTGCAGGCCGCGCTGCGTGCCAAGCAAAAGAACGACGTAGAAGGCGCCA
  AGATGCACCTGCGCCAGGCCAAAGGGCTAGAGCCCATGCTAGAGGCCTCTCGCAATGGACTGCCTGTGGA
  CATTGCCAAGGTGCCACCTGCTCCTGTCAACAAGGACGACTTTGTGCTGGTGCAGCGGCCTGGCCCAGGC
  TTGTCTCAGGAAGCTGTGCGTCGCTATGGGGAACTTACCAAGCTCCTGAGACAGCAACATGAAATGTGTC
  TAAACCACTCCACACAGTTCACCCACCTGGGCAACATTGCTGAAACCATTAAGTTCGAGAAGCTGGCAGA
  AGACTGTAAGCGGAGCATGGACACCTTAAAACAAGCCTTCGCCCGCAGTCTGCCCACACCCGCAGCCCGC
  TTTGAGCAGAGGACCTTCAGTGTCATCAAGGTCTTTCCGGACTTGAGCAACAGTGACATGCTCCTGTTTA
  TCGTGAAGGGCATCAACTTGCCCACACCCACAGGGCTGTCCCCCAGTGACCTGGATGCCTTTGTCCGCTT
  TGACTTCCCTTATCCCAATGTGGAAGAAGCTCAGAAAGACAAGACCAGTGTGATCAAAAACACAGACTCC
  CCTGAATTTAAGGAGCAGTTCAAACTCTGCATCAACCGTGGCCACCGTGGCTTCCGAAGGGCCATCCAAA
  CCAAGGGCATCAAGTTCGAAGTGGTCCACAAGGGGGGGCTGTTCAAGACGGACAGGGTGCTAGGTACAGC
  CCAGCTGAAGCTGGGTACGTTGGAAACAGCTTGTGAAGTCCACGAGATCCTGGAGGTTTTGGATGGACGC
  CGACCCACGGGGGGGAGGCTTGAAGTGATGGTTCGCATCCGGGAGCCACTGACAGCCCAGCAGTTGGAAA
  CTACAACTGAGAGGTGGCTGGTCATTGATCACATCCCAGCAGCTATGCCCACTGTCACTGGGCCCAAAGC
  AAAGGCTCCTCTCATACCGGCGTCTTCAAGGGAAGCAGGCAACAGATCAGCACGGCCCCTGCATAGCCTT
  AGCGTGTTGGCCTTTGACCAAGAGCGGCTAGAAAGGAAGATCCTGGCCCTGAGGCAGGCACGCCGGCCTG
  TGCCTCCAGAAGTGGCCCAGCAGTACCAGGACGTAGTACAGCGTAGCCAATGGCAGAGGGCACAGCTGGA
  GCAGGGGGGTGCTGCCCTCCGCAGGGAGTATGCAAGCCATCTGGAGCGCCAGCTGCACTTCTATACAGAG
  GCTGCCCGGCGCCTGGGCTACGATGGAAGCAGGGAGGCTGCAAAGGAGGCATTGTATCGGCGGAACCTGG
  TGGAGAGCGAGCTGCAGCGACTCCGCAGGTGA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_145970
• Insert Size: 2832 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_145970.1, NP_666082.2
• RefSeq Size: 3349 bp
• RefSeq ORF: 2832 bp
• Locus ID: 212139
• UniProt ID: Q8K1A6
• Cytogenetics: 8 C2
• Gene Summary: Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses.[UniProtKB/Swiss-Prot Function]