Srrm4 (NM_026886) Mouse Untagged Clone

CAT#: MC219631

Srrm4 (untagged) - Mouse serine/arginine repetitive matrix 4 (Srrm4), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Srrm4
• Synonyms: 1500001A10Rik; B230202K19Rik; bv; mKIAA1853; nSR100
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC219631 representing NM_026886
  Red=Cloning site Blue=ORF Orange=Stop codon
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGCTAGCCTGCAGCAGGGCGAGAAACAGCTGTTTGAGAAGTTCTGGAAAGGGACCTTCAAAGCAGTGG
  CCACTCCGCGTCCCGAGAGCATCATCGTCGCCAGTATCACAGCCCGCAAGCCGATGCCAAGGACAGAGCC
  CCAGAGCAGTCTCTTGCTCCCAGATCAGGATGGACCTTCAGAAAAGCTGGGCCAACATCTGGCCCCTGAG
  GCCCTGGGTACCAACAGCTGGGGAAGAGAGAAGGCCTGCAGGGAACTGGATCCTGCCAGAGCACACAGTG
  CCTCTCAAGACAGAGACCCGACACCACCACCTTCCTCCAGGGGGAAAAAGAAAAAGAAGAAATCAACCAG
  GAAAAAGAGGAGGAGGTCCCCGTCCTACAGCCCATCACCAGTCAAGAAGAAGAAGAAGAAAAGCTCCAAG
  AAACATAAGCGACACAGGTCTTTCTCCAAGAAAAGGAGACACAGCTCCTGTAGCCCTAAAAGCAAAAGAC
  GGGAAGAGAAGAGGCACAAAAAACAATCTCGAAGCCGGAAGTCTCACCGACATAGACATCACCGATGCCC
  CTCAAGGTCCCAGAGTTCGGAACTGCGCTCCCCCAGCTGCGAGAGCAGGCATCGAGGTCGGTCCCCTGAG
  GAAGGGCGGAAATCCCGCCGAACACACTCCCGCCGCTGCTCCAAGAACCACTGCAAGGTCAGCCCAGACG
  CCCGGTCCAGCCACCTGCCCAGCCAGCCCCTCCCGAGGCTCGGCTTCCTGTCAGCCAGGGGTGTAATCAC
  TGGGTCGGGGTCCGCGGCTGACCTCTTTAGCAAATCGGCCAGCCCTCTCGCCGCCACCCGAGGGCGCTCG
  CAGGAGTACGACTCGGGCAATGACACGTCCTCGCCGCCCTCCACGCAAACCAGCTCGGCCAGGTCTCGGG
  GCCAGGAGAAGGGGAGTCCCGGTGGGGATCTAAGCAAGAGTCGAGACCTCAACTGTGGCAACACCTCCGA
  TTCAGGGAACTCCTTCACCACCTCCTCCCCCCAGAACAAGGGGGCTGTCTTGGAGACTGTCTCTCCCGCC
  TGCAGGAGCAGAGAGTCAAGAGGGTTTCAGTCCCCATGTCTCCAGTGTGCAGAGGTGAAGAAGTCTAGTT
  TGGTCCCATCCACAGCCCGGAGCTCCCCCATCAAAGAGTGCTCCCGTAGCTCCTCCTACACCAGCACTCG
  ATCCTCCAGTCCCTCATCCAGGTCCCCAAACCCCAGAGCTTCCCCCAGGTACACCCGGAGTCGGTCCACC
  TCCTCTGAAAAAAGGTCCTACTCTCGCTCTCCCAGCTATTCGTCCAAGTCTGGCAAGAGGAGCCCACCTA
  GCAGAAGCTCCAGGTCTCGTCGAAGTCCCAGCTACTCTCGCTACAGCCCCAGCAGGGAACGGGACCTAAA
  GTATGGTGAGAAAGAACCACAGCCCCGAGAACGTGCGCGCAGGAGGCGACGGTCCTACTCACCCATGAGG
  AAGCGCAGGAGAGACTCCCCAAGCCACCTGGAGGCTCGGAGGATAACCAGTGCCCGCAAACGCCCCATCC
  CCTACTACCGACCCAGCCCCTCCTCGTCCAGCAGCCTCAGCAGCGCCTCCTCCTGGTACAGCAGCAGCAG
  CAGCAGCAGCAGCAGTAGCAGCCGCTCCCCTAGCCGCAGTTACTCCCGGAGCCGGAGTCCCAGTCGGAGC
  CACAGCAGCCGGAGCCAGACCCGGAGCAGGACGCGGACCAGCCGCAGCTCCAGTTCTCGCAGCCTCAGCC
  TGGGCTCCCGGAGCCGCAGTCGGAACCGGAGCCTGAGCTACAGCTCGGCAGAAAGCTATGCCAGCACGAG
  GCGCTAA
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_026886
• Insert Size: 1827 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_026886.3, NP_081162.1
• RefSeq Size: 7476 bp
• RefSeq ORF: 1827 bp
• Locus ID: 68955
• UniProt ID: Q8BKA3
• Cytogenetics: 5 F
• Gene Summary: Splicing factor specifically required for neural cell differentiation. Acts in conjunction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts (PubMed:19737518). Promotes alternative splicing of REST transcripts to produce REST isoform 2 (REST4) with greatly reduced repressive activity, thereby activating expression of REST targets in neural cells (PubMed:21884984). Plays an important role during embryonic development as well as in the proper functioning of the adult nervous system. Regulates alternative splicing events in genes with important neuronal functions (PubMed:25838543).[UniProtKB/Swiss-Prot Function]