Fermt3 (NM_153795) Mouse Untagged Clone

CAT#: MC204146

Fermt3 (untagged) - Mouse fermitin family homolog 3 (Drosophila) (Fermt3), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Fermt3
• Synonyms: C79673; Kindlin3
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC032204
  CCACGCGTCCGCCAGCAACAGCCCGCCCTGGGGAGGGACTAGTACAACTTTCATGATAAGGCCACTACAG GCTGACCTCTGAAGGAAGCAACTGAGCAGGACCAGGCCAGACCAGGGTAACAGGTGTCCCACTGCCACCT GCAGCTGCAGCCCGTTGCAGGCTAGCAGAAACAGCCGCAGCCATGGCGGGTATGAAGACAGCCTCCGGGG ACTATATCGACTCTTCCTGGGAGCTGAGGGTGTTTGTGGGCGAGGAGGACCCTGAGGCCCAGTCTGTCAC ACTCCGAGTCACGGGGGAGTCGCACATTGGTGGGGTACTTCTGAAGATCGTGGAGGAAATCAATCGCAAG CAGGACTGGTCTGACCATGCCATTTGGTGGGAGCAGAAGAGACAGTGGCTGCTGCAGACACACTGGACGC TGGACAAGTACGGGATTCTGGCCGATGCCCGCCTCTTCTTTGGGCCACAGCACCGACCTGTCATCCTGCG ACTGCCCAACAGACGTGTGCTGCGGCTTCGGGCCAGTTTCTCCAAGCCCCTCTTCCAGACGGTGGCTGCC ATCTGCCGCCTCCTCAGTATCAGGCACCCAGAGGAGCTGTCTCTGCTGCGTGCTCCAGAGAAGAAGGAGA AGAAGAAGAAGGAGAAGGAGCCTGAAGAGGAGGTGCATGACCTGACAAAGGTTGTCTTAGCTGGCGGTGT GGCACCCACTTTATTCAGAGGCATGCCAGCACACTTCTCGGACAGCGCCCAGACTGAGGCTTGTTACCAC ATGCTGAGCCGGCCACAGCCGGCACCTGACCCTCTCCTGCTCCAGCGCCTGCCAAGGCCCAGCTCCCTGC CTGACAAGACCCAGCTCCACAGCAGGTGGCTGGATTCATCTCGGTGCCTCATGCAGCAAGGTATCAAGGC CGGGGATGTGCTTTGGCTGCGATTTAAGTACTACAGCTTTTTTGACCTGGATCCCAAGACAGACCCTGTG CGGCTGACCCAGCTGTATGAGCAGGCCCGCTGGGACTTACTGACAGAGGAGATCGACTGCACTGAAGAAG AGATGATGGTGTTTGCTGCCCTGCAGTACCACATCAACAAACTGACCCTGAGCGGGGATGTGGGTGAGCT GGCCTCTGGGGACCTGGGACTGGATGACCTGGATGCAGCCCTGAACAACCTGGAGGTGAAGCTGAAGGGG TCAGCACCCTCAGACATGCTGGATAGTCTCACTACCATCCCAGAACTCAAGGACCATCTCCGGATCTTCC GGCCCCGGAAGCTGACCCTGAAGGGCTACCGCCAGTACTGGGTGGTATTTAAGGACACCACACTGTCCTA CTATAAGAGCCAAGATGAAGCACCGGGGGACCCTACCCAGCAGCTCAACCTCAAGGGCTGTGAGGTGGTC CCTGATGTCAATGTCTCTGGCCAGAAGTTCTGCATCAAACTCCTGGTACCCTCACCAGAGGGCATGAGTG AGATCTACCTGAGGTGCCAGGATGAACAGCAGTACGCACAGTGGATGGCTGCCTGCCGACTGGCCTCCAA GGGCCGCACCATGGCGGACAGCAGCTATGCCAGCGAGGTGCAGGCCATTCTGGCCTTCCTCAGCCTGCAG CGGGCAGGTGGTAGCAATGGAGGCTCAGGGAACAAACCTCAAGGTCCTGAAGCCCCTGCTGAGGGCCTTA ACCCCTATGGCCTCGTGGCTCCTCGGTTCCAGCGAAAGTTCAAGGCCAAGCAGCTCACCCCAAGGATCCT GGAAGCTCACCAAAACGTGGCCCAACTCTCACTGACCGAGGCCCAGCTGCGCTTTATCCAGGCCTGGCAA TCCTTGCCCGACTTTGGCATCTCCTATGTGATGGTCAGGTTCAAGGGCAGCAGGAAAGATGAGATCCTAG GCATTGCCAACAACCGACTCATCCGGATTGATCTGGCCGTGGGTGACGTGGTCAAGACCTGGCGCTTCAG CAACATGCGGCAATGGAACGTCAACTGGGACATACGGCAGGTGGCCATTGAGTTCGATGAACACATCAAT GTGGCCTTCAGCTGTGTGTCTGCTAGCTGCCGCATCGTGCACGAGTACATCGGGGGTTACATCTTCCTGT CCACCCGAGAGCGGGCCCGAGGGGAAGAGCTGGATGAGGATCTGTTCCTGCAGCTTACAGGAGGCCATGA GGCCTTCTGAGGGCAGCCCCTGCTCCACTCACCACCTCCAGGGACCCCCCAAAGGCCACACCCACCTGAA CACACTGCTCCATCACTCCCGGGATGTACACTGCTGGGCAACTTCACTTGTTGTCACCAGGCAGGCCAGG GCCCTCGCTGGGGTAGGTGCTACCACCAGCCAGCCTAGGGATGATGGGCCCTGAGCCACACAGAGCCCCT CCTCTCACCCTGTTGGCAGAAGCTCACACCCCCGACCTCTATGTAGTCCCTAAGCACACGACGAATGCCA GACGAAGCACACGACGAATGCCAGACACGGATGAGGAACCACAAATCCTGGTTTGAAGCTGGACTTTCTT TCTGTGTCTGTTTCAGGTTTTTTAATAAATAAATATTTTATTGTTGAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_153795
• Insert Size: 1998 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC032204, AAH32204
• RefSeq Size: 2635 bp
• RefSeq ORF: 1998 bp
• Locus ID: 108101
• UniProt ID: Q8K1B8
• Cytogenetics: 19 A
• Gene Summary: Plays a central role in cell adhesion in hematopoietic cells (By similarity). Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3) (PubMed:18278053). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells (PubMed:19234461). Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (PubMed:18278053).[UniProtKB/Swiss-Prot Function]