Slc4a8 (NM_021530) Mouse Untagged Clone

CAT#: MC203205

Slc4a8 (untagged) - Mouse solute carrier family 4 (anion exchanger), member 8 (Slc4a8), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Slc4a8
• Synonyms: AW493845; C230026C11; kNBC-3; NDCBE
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC030388
  CCACGCGTCCGCGGTTGATGGTTGACCGATCCTTGGATCCAGGGTAGGGGTCGCTGCGCGTGCGATCGTC TCACACTGGACTACAGGGCGCGGACTGCTGCAGCTCAACCTGGAACCTACCGGCGAGACCAGGCTCCGCC CGGCCATGCCCGCCGGGAGCAACGAGCCGGACGGCGTCCTCAGCTATCAGAGGCCAGATGAGGAAGCTGT GGTGGATCAGGGTGGGACCAGCACAATTCTCAACATTCACTATGAGAAAGAAGAGTTGGAAGGTCATAGA ACTCTGTATGTGGGGGTTCGGATGCCGCTGGGGAGGCAGAGCCATCGGCACCACCGCACTCATGGCCAGA AGCACCGGAGACGAGGAGGGCGGGGCAAAGGAGCCAGCCAGGGCGAGGAGGGCTTGGAAGCCTTGGCCCA CGACACCCCGTCTCAGCGTGTTCAGTTCATTCTTGGCACTGAGGAAGATGAAGAACATGTGCCTCATGAG CTCTTCACAGAGCTGGACGAGATCTGTATGAAAGAGGGGGAAGATGCTGAGTGGAAGGAGACGGCCAGGT GGCTGAAGTTTGAAGAGGATGTGGAGGACGGGGGAGAGCGCTGGAGCAAGCCTTACGTGGCCACGCTCTC TCTGCACAGCCTGTTTGAGCTGAGGAGCTGCCTCATCAACGGCTCTGTGCTTCTGGACATGCGTGCAAGT AGCATAGAGGAGATCTCAGACCTGATCCTGGACCAGCAGGAGCTGCTCCGAGACCTGAGCGACAGCGTGA GGGTTAAAGTGCGGGAAGCCCTGCTGAAGAAGCACCACCACCAGAACGAGAGGAGGAGGAACAACCTCAT CCCCATCGTCCGCTCCTTCGCTGAGGTTGGCAAGAAGCAGTCTGACCCGCACTCCATGGACAGAGATGGG CAAACGGTGTCTCCTCAGTCAGCTACAAACCTTGAAGTGAAGAATGGTGTGAACTGTGAGCACAGCCCTG TGGATCTAAGCAAGGTGGATCTTCACTTCATGAAAAAAATTCCCACGGGGGCAGAGGCCTCCAATGTCCT GGTGGGAGAGGTGGATACGCTGGACCGGCCCATCGTGGCCTTCGTGAGGCTCTCCCCGGCTGTGCTGCTC TCTGGCCTGACGGAAGTGCCCATCCCAACGAGGTTTTTGTTTATCTTACTGGGCCCAGTGGGAAAAGGGC AGCAGTACCATGAGATTGGCAGGTCCATGGCCACCATCATGACGGACGAGATTTTTCATGATGTGGCATA TAAAGCAAAGGAACGCGATGACCTCCTGGCAGGGATTGACGAGTTCCTGGACCAGGTGACGGTGCTTCCG CCAGGGGAGTGGGACCCATCTATTAGAATTGAGCCACCCAAGAATGTCCCTTCCCAGGAAAAAAGGAAAA TGCCCGGTGTTCCAAACGGAAACGTTTGCCACATAGAACCAGAGCCACATGGGGGGCACAGTGGGCCAGA ACTGGAGCGGACTGGGCGGCTGTTTGGGGGCTTGGTGCTGGATGTCAAGCGGAAGGCTCCCTGGTACTGG AGTGACTACCGGGATGCTCTCAGCTTACAGTGTCTGGCCTCCTTCCTGTTCCTGTACTGTGCCTGCATGT CGCCCGTTATCACCTTCGGGGGACTGCTGGGAGAAGCCACTGAAGGACGCATAAGTGCGATTGAGTCGTT GTTTGGAGCGTCCATGACGGGGATTGCCTACTCTCTGTTTGCTGGGCAGCCTCTCACCATCCTGGGAAGC ACGGGGCCCGTGCTGGTGTTTGAAAAGATTTTGTTCAAATTCTGCAAGGACTATGCCCTTTCGTACCTGT CCCTGCGGGCTCTCATCGGGCTGTGGACTGCCTTCCTGTGCATCGTCCTGGTGGCCACGGATGCCAGCTC CCTCGTCTGCTACATTACCCGCTTCACCGAGGAAGCGTTTGCCTCCCTGATTTGTATCATCTTCATCTAT GAAGCCATAGAAAAGCTGATCCACCTGGCAGAGACCTACCCCATCCACATGCACAGCCAGCTGGACCACC TGAGCCTCTATTACTGCAGGTGTGTGCTCCCGGAGAATCCAAACAACCACACCTTACAGTATTGGAAGGA CCACAACATCCTGGCTGCCGAAGTGAACTGGGCAAACCTGACAGTCAGCGAATGCCAGGAGATGCACGGG GAGTTCATGGGATCTGCCTGCGGTCACCACGGACCCTACACGCCCGACGTGCTCTTTTGGTCCTGCATTC TGTTCTTCGCCACCTTCATCGTCTCCAGCACCTTAAAGACATTTAAGACAAGCCGCTACTTCCCGACCAG GGTCCGCTCCATGGTGAGTGACTTCGCCGTGTTCCTCACCATCTTCACCATGGTGGTCCTTGACTTTCTG ATTGGCGTCCCGTCGCCAAAGCTTCAGGTTCCCAATGTGTTCAAGCCAACAAGGGACGATCGAGGATGGT TTATTAATCCCATTGGCCCCAATCCCTGGTGGACTGTGATAGCCGCAATTATCCCAGCTCTCCTGTGCAC TATCCTGATATTCATGGACCAGCAGATCACCGCTGTCATCATTAACAGGAAGGAACACAAGCTCAAGAAA GGCTGTGGCTACCACCTGGACCTGCTCATGGTGGCCGTCATGCTGGGAGTTTGCTCCATCATGGGCCTGC CTTGGTTTGTGGCCGCGACCGTCCTGTCCATTACCCATGTGAACAGCCTCAAGCTGGAATCCGAATGCTC TGCCCCCGGGGAGCAGCCCAAGTTCTTGGGCATCCGGGAACAGAGAGTCACAGGGCTTATGATCTTCGTG CTGATGGGCTGCTCAGTCTTCATGACAGCTGTCTTAAAGTTTATCCCGATGCCAGTGCTCTACGGAGTTT TCCTCTACATGGGAGTCTCTTCGCTACAAGGAATCCAGTTCTTCGACCGTCTGAAGCTTTTCGGGATGCC TGCAAAACACCAGCCAGACTTCATCTACCTGCGGCACGTGCCGCTGCGCAAGGTGCACCTGTTCACGCTA GTGCAGCTCACCTGCCTCGTCCTGCTCTGGGTCATCAAGGCATCGCCGGCCGCCATTGTTTTCCCAATGA TGGTGCTGGCCTTGGTCTTCGTCAGGAAAGTCATGGATCTCTGCTTCTCCAAGCGTGAGCTAAGCTGGCT GGACGACCTCATGCCTGAGAGCAAAAAGAAGAAGCTGGACGATGCGAAGAAGAAGGAGGAGGAGGAGGCC GAGAAGATGTTGGACATTGGGGGTGACAAGTTTCCCCTGGAAAGCAGGAAGCTGCTAAGTAGTCCTGGCA AGAGCAGCAGCTTCAGATGTGACCCTTCTGAGATTAATATATCAGATGAAATGCCTAAAACCACGGTCTG GAAGGCTCTCAGCATAAATTCCGGAAATACAAAAGAAAAAAGCCCCTTCAACTGAGAGTCTCTGCTGAGT GGAAGATTTGGACCATGAGGTGCCTCGGAGAAGTTCTGGGTTTTAACAAAATGGCGAGTCTCTCCGGGAA GAAGCCGAGCTGAGTCTGGCCCCGTTCTTGGTCATCTCAAAGCCATGCCACATGGAAGCATTCAGTCACT CCCGGTGTGCGTTTGGAGGACATCCAGCTACCCACATACCAGCAGCCAGGCGCCAGTCGGGTCATGGTGG GGCCGCCTCCCGCTGCCTCCTTTCCTCTTCCTTCTCTCTCTTCAGAGCTGCCATCATTAAAGAGCCAGCT TCCATTTTCAGACAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_021530
• Insert Size: 3270 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC030388, AAH30388
• RefSeq Size: 3738 bp
• RefSeq ORF: 3270 bp
• Locus ID: 59033
• UniProt ID: Q8JZR6
• Cytogenetics: 15 F1
• Gene Summary: Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.[UniProtKB/Swiss-Prot Function]