Abhd2 (NM_018811) Mouse Untagged Clone

CAT#: MC202088

Abhd2 (untagged) - Mouse abhydrolase domain containing 2 (Abhd2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Abhd2
• Synonyms: 2210009N18Rik; Labh-2; LABH2
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC027098 sequence for NM_018811
  ACCGGACTCCGGGCGGGTTGGACTGCTGGAGTCAATGAGAGAAGCTTTTAGGTTAATTTGAATATAAGAT CAGATCTGATTGGCCCACCTGGACACCCCTTCAAGGAAAGCCCGTATTCTCCGAGAGAGGAATAAGCGAC ATAGATCAAGATGAATGCCATGCTAGAGACCCCCGAGCTCCCCGCCGTGTTTGATGGGGTGAAGCTGGCT GCCGTAGCTGCCGTTCTCTACGTCATCGTGCGGTGTTTGAACCTGAAGAGCCCTACTGCCCCTCCTGACC TCTACTTCCAGGACTCCGGGCTCTCACGTTTCCTGCTCAAATCCTGTCCTCTTCTGACCAAAGAATACAT TCCACCACTGATCTGGGGGAAAAGCGGACATATCCAGACAGCCTTGTATGGGAAGATGGGGAGGGTGAGG TCACCACACCCTTACGGGCACCGCAAGTTCATCACCATGTCGGATGGTGCCACTTCTACCTTCGACCTCT TCGAGCCCCTGGCTGAGCACTGTGTTGGAGATGACATCACCATGGTCATCTGTCCTGGAATTGCCAACCA CAGCGAGAAGCAGTATATCCGAACCTTCGTTGACTATGCCCAGAAAAATGGCTACCGGTGCGCAGTGCTA AACCACCTGGGAGCCCTCCCCAACATTGAGCTGACCTCCCCACGAATGTTCACCTATGGCTGCACGTGGG AATTTGGAGCCATGGTGAACTACATCAAGAGGACATATCCCCAGACCCAGCTGGTCGTCGTGGGCTTCAG CCTGGGTGGTAACATCGTGTGCAAATACTTGGGGGAGACGCAGGCAAACCAGGAAAAGGTCCTGTGCTGT GTCAGTGTGTGCCAGGGGTACAGCGCACTGAGGGCCCAGGAGACCTTCATGCAGTGGGACCAGTGCCGCA GGTTCTACAACTTCCTCATGGCCGACAACATGAAGAAGATCATCCTGTCTCACAGACAAGCTCTCTTTGG AGACCACGTTAAGAAACCCCAGAGCCTGGAGGACACGGACTTGAGCCGGCTGTACACAGCAACATCCCTG ATGCAGATTGATGACAATGTGATGAGAAAGTTCCATGGCTATAATTCCCTGAAGGAATACTATGAGGAAG AGAGCTGCATGAGGTACCTGCACAGGATATATGTGCCTCTCATGCTGGTTAATGCAGCTGACGACCCCTT GGTGCACGAAAGCCTTCTAACCATTCCAAAGTCTCTCTCAGAGAAACGGGAGAATGTCATGTTCGTGCTG CCTCTGCATGGGGGCCACCTGGGCTTCTTCGAGGGCTCCGTGCTGTTCCCCGAGCCGCTGACATGGATGG ATAAGCTGGTAGTGGAGTATGCCAATGCCATTTGCCAATGGGAAAGGAATAAGTCCCAGTGCTCAGACAC GGAGCAGATGGAGGCCGAGTTGGAATGAGGTCTCTGGACTCGGCGTGCTCCAGCGGCCCTCCTCTGGAAC CCACGTCCCTTTGACGGCTGTTTCAGGTCTCCCAGTGACCTGGATCTGACCTCATACCATCAGTGGGGGG TTACCCATCATGCAACCTGTCTCAAGTAGGCGGCTCTCCCTGGGAGCTCCAGGCTATTTTTGTGCTTAGT TACGGGTTTTCTCCATTGCATCGTTAGCCATGGTGACAAGCTACAAGATTCTCACCCTTCTGTCCAGTTT CAGTATCTGATTGCTTTCACGCTGGTTAACATCTAGTTTTCCTAGTAAGGAGCGAGTCTGAACTATAGTT TTGCTTTGCCAATCAAAGGCCTTTTCCTGAGAACAGTGAAGGATATACGTCACTCTGTGATGGATGTATG CGCCGTACTAGAGTCCCCACCAAGAAGTCAGCATCCCTCGTGCTGAAGAAATTACTCAGCTTGGGAGTCT GAGAACCTGGGCCTTCCTGGGCCTGAGTTTTGCCTGTGAAACAAAGGAAATTCTCTGAATCAAAAAAAAA AAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_018811
• Insert Size: 1278 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC027098, AAH27098
• RefSeq Size: 1966 bp
• RefSeq ORF: 1278 bp
• Locus ID: 54608
• UniProt ID: Q9QXM0
• Cytogenetics: 7 D2
• Gene Summary: Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation (By similarity). Involved in acrosomal reaction (Probable). May also play a role in smooth muscle cells migration (PubMed:15721306).[UniProtKB/Swiss-Prot Function]