Ap4b1 (NM_026193) Mouse Untagged Clone

CAT#: MC202043

Ap4b1 (untagged) - Mouse adaptor-related protein complex AP-4, beta 1 (Ap4b1), transcript variant 1, (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Ap4b1
• Synonyms: 1810038H16Rik; Ap4b4; AV004952
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC054092 sequence for NM_026193
  GACAAGAGGTAATCCCTGCGCTCGGCGCTCGGCGCGACCCGGAAAGCTGCTCCTTGTGTCTCAGGGCGAC GGGGCGGGATTTCCGCAGGAAGCTGTCTGGGGTGTCCTCGGCCACTGGGACTAGATTCCCAGGGAGGAGG CTGTGCTAGGCTCCCACATCGAAATTAGGAGGAGCCCACGAGTTCCCTACGGGTCTGTGGAAACTGTCCC GTGAGTGTTGGCGACGATGCCATACCTTGGCTCTGAGGACGTGGTGAAGGAACTGAAGAAGGCTCTGTGT AACCCTCATATTCAGGCTGATAGGCTGCGCTACCGGAATGTCATCCAGCGAGTTATTAGGCACATGACTC AGGGCTTGGACATGTCTGATGTTTTCATGGAAATGGTAAAGGCCAGTGCCACTGTAGATATTGTTCAGAA AAAGTTGGTTTATCTGTATATGGGCACATACGCACCTTTAAAACCAGATCTAGCACTCTTGGCCATCAAT ACGCTCTGCAAAGACTGCTCAGACCCCAACCCAATGGTGCGAGGACTGGCACTACGGAGTATGTGTAGCC TCAGGATGCCTGGTGTGCAGGAATATATCCAGCAGCCTGTTGTTAACGGTCTGCGTGATAAAGCTTCATA TGTCAGAAGAGTAGCAGTCCTCGGCTGTGCCAAAATGCATAATCTTCACGGAGACTCTGAAGTGGATGGT GCTCTCGTCAATGAGTTGTACAGTCTTCTGCGTGACCAGGATCCAATTGTGGTTGTGAACTGTCTGAGGT CTCTAGAGGAAATTTTAAAGCAGGAAGGAGGTGTTGTCATTAATAAGCCCATTGCCCACCATCTCTTAAA TAGAATGTCAAAACTGGACCAGTGGGGCCAGGCTGAAGTACTGAACTTTCTGCTCCGCTACCAACCCCGC AGTGAGGAGGAACTGTTTGATATTCTCAATTTGTTGGACAGCTATCTCAAGAGCAGCAGTACTGGCGTGG TGATGGGAGCCACCAAATTCTTTCTGATTTTGGCAAAAAAGTTCCCCCACGTGCAGACTGATGTGCTTGT GCGAGTCAAGGGGCCCTTGCTGGCCGCCTGCTCCTCAGAGAGCCGTGAGCTCTGTTTTGCTGCTCTCTGC CATGTCCGCCAGGTCTTGCACAGTTTGCCAGGTCACTTTAGCAGTCACTACAAAAAGTTTTTTTGCTCTT ACTCGGAACCCCACTACATCAAGCTCCAGAAGGTGGAGGTGCTGTGCGAGCTGGTGAATGACGAGAACGT GCAGCAGGTGCTGGAAGAGCTGCGTGGCTACTGCACTGACGTGGCTGCTGACTTTGCACAGGCTGCCATC TTCGCCATAGGTAGCATTGCCAAGACTTACACAGATCAATGTGTGCAGATTCTAACAGAGTTGCTGGGAC TTCGACAAGAACATATCACTACTGTGGTCGTGCAGACTTTCCGAGACCTGGTCTGGCTATGCCCTCAGTG TACTGAAGCTGTGTGTCAGGCTCTGCCCGGCTGTGAGGAGAGCATTCAAGACAGTGAGGGGAAACAGGCA CTTATTTGGTTACTTGGGGTCCACGGGGAAAAAATCCCCAATGCTCCTTATGTGTTGGAGGACTTTGTAG ACAACGTGAAGTCAGAGACATTTCCCGCTGTTAAGATGGAGCTACTGACCGCACTGATGCGCCTTGTCCT CTCGCGCCCGGCTGAGTGCCAGGACATGCTGGGACGGCTGCTGCATTACTGCATAGAGGAAGAAAAGGAT ATGGCTGTACGGGACCGGGGTCTCTTCTATTACCGCCTCCTGTTAGTTGGCATTGATAAAGTTAAGCAGA TCCTGTGTAGTCCTAAGTCTGACCCTTCTCTTGGACTTTTGGAGGATCAGCCGGAACGACCAGTAAATAG CTGGGCTTCAGACTTCAACACACTGGCGCCAGTGTATGGCAGAGCCCACTGGGCAACTATCTCTAAATGC CAGCAGGTAGAGCGGCATCGCCTTGAGCTTCCCCACAATGCATCCTTTGCCACATCAGGGCACTTGATTT CCGAGGAGAACAAAAAAGGTGCACAAGAACCTGATTCTGACACTCTCATGCTGGTCCCTAATCTCCAGCT TACTGCTGAGTATTTTGAGAAGACGTGGCTTAGCCTCAGAGTTAGTTACCAGCAGGTGTTTCCTTGGCAG GGAGAAGTCCAGCCTGACACTCTACAAATGGCTCTAAAAGTAGTGAACATTCAGACCATCGCAATGAGCA GAGCTGGGGCACAGCCCTGGAAAGCCTACCTCAGTGCTCAGGATGATACTGGCGGCCTTTTCTTAGCTGA ATTGCTACTGAAGCCTGAGAACTCAGAGATGCAAATCTCTGTGAAGCAAAGTAAGGCAAGGACTGAATCC CTGCATGGTTTTGTTTCTGTCCTGGAAACTGTGATTGGAACAGTTGGAGACATAAAATCTTAACAGAGTT CCTTCATTGTCTTAAAAAGCTGCTCGTAAGTCCACATATTAACTTCAAAAGAGAGTGGGAGGTCTGGGAA CCCAGCTCTTATGTTTACCCAAAGTTTACGTTGTTCTTTTCAAGCCTGTCAGGAATTGATCCCATTTTAA AAGGAGAATGTATACTGTCATATTAGTAGATAAGAATGGGGTGAAGATAGGCTGGGGACACTTCTCTGAT CATTTTAGCGGTTGTAATATTTATTAAATATACCTGGCATTTGTGGAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_026193
• Insert Size: 2217 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC054092, AAH54092
• RefSeq Size: 2725 bp
• RefSeq ORF: 2217 bp
• Locus ID: 67489
• UniProt ID: Q9WV76
• Cytogenetics: 3 F2.2
• Gene Summary: Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system (By similarity). It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons (PubMed:18341993). AP-4 is involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos, but may also recognize other types of sorting signal (By similarity).[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode the same isoform (a).