Ap4b1 (NM_026193) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR216173L3V
- LentiORF®
Lenti ORF particles, Ap4b1 (Myc-DDK-tagged) - Mouse adaptor-related protein complex AP-4, beta 1 (Ap4b1), transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: mGFP w/ Puro
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USD 365.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | Ap4b1 |
Synonyms | 1810038H16Rik; Ap4b4; AV004952 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_026193 |
ORF Size | 2217 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR216173).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_026193.2, NP_080469.2 |
RefSeq Size | 2914 bp |
RefSeq ORF | 2217 bp |
Locus ID | 67489 |
UniProt ID | Q9WV76 |
Cytogenetics | 3 F2.2 |
Gene Summary | Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system (By similarity). It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons (PubMed:18341993). AP-4 is involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos, but may also recognize other types of sorting signal (By similarity).[UniProtKB/Swiss-Prot Function] |
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