Human GFAP ELISA KIT (1 x 96 wells)
Human GFAP ELISA Kit for the detection of Human GFAP in serum, plasma, and other biological fluids.
|Format||8x12 divisible strips|
|Assay Type||Sandwich ELISA kit of Quantitative Detection for Human GFAP|
|Assay Length||4 hours incubations; 0.5 hour washing and analyzing samples|
|Sample Type||Human serum, plasma and other biological fluids.|
|Specificity||This kit is used for quantitative detection of Human GFAP|
|Cross Reactivity||There is no detectable cross-reactivity with other relevant proteins.|
|Interference||No significant interference observed with available related molecules.|
|Background||Glial fibrillary acidic protein (GFAP) is a type III intermediate filament (IF) protein that is expressed by numerous cell types of the central nervous system (CNS), including astrocytes and ependymal cells during development. GFAP has also been found to be expressed in glomeruli and peritubular fibroblasts, Leydig cells of the testis, keratinocytes, osteocytes and chondrocytes. It has been shown to be important in the pathogenesis of Alexander disease and in repair after CNS injury. Decreases in GFAP expression have been reported in Down's syndrome, schizophrenia, bipolar disorder and depression. GFAP levels are already used as a marker for the activation of astrocytes (AS) following injury or stress in the CNS. Serum GFAP shows promise as a biomarker of disease severity in frontotemporal lobar degeneration (FTLD), and might be a suitable multiple sclerosis progression biomarker. In addition, GFAP has been used as a classical marker of astrocytoma and a diagnostic biomarker for glioblastoma multiforme (GBM).|
Data image for Human GFAP ELISA KIT.
|Assay Kit Resources|