c Fos (FOS) Mouse Monoclonal Antibody [Clone ID: UMAB221]

CAT#: UM800113

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FOS mouse monoclonal antibody,clone UMAB221



  View other "UMAB221" antibodies (2)

USD 564.00


Availability*
In Stock

Size
    • 100 ul


Specifications

Product Data
Clone Name UMAB221
Applications 10k-ChIP, IHC, WB
Recommended Dilution IHC 1:100~200
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human FOS (NP_005243) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 40.5 kDa
Gene Name Homo sapiens Fos proto-oncogene, AP-1 transcription factor subunit (FOS), mRNA.
Background The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008]
Synonyms AP-1; C-FOS; p55
Reference Data
Protein Families Druggable Genome, Transcription Factors
Protein Pathways B cell receptor signaling pathway, Colorectal cancer, MAPK signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway

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