NMDAR2A (GRIN2A) Rabbit Polyclonal Antibody

CAT#: TA890121

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Rabbit Polyclonal anti-GRIN2A Antibody


 Product Datasheet for 'TA890121'

USD 345.00


Availability*
In Stock

Size
    • 100 ul


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Specifications

Product Data
Applications WB
Recommend Dilution WB: 1:500~2000
Reactivity Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Recombinant protein of human GRIN2A
Formulation PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration 2.23 mg/ml
Purification Purified from Rabbit serum by antigen affinity chromatography
Predicted Protein Size 165.28 kDa
Gene Name glutamate ionotropic receptor NMDA type subunit 2A
Background This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Synonyms EPND; FESD; GluN2A; LKS; NMDAR2A; NR2A
Reference Data
Protein Families Druggable Genome, Ion Channels: Glutamate Receptors, Ion Channels: Sodium, Transmembrane
Protein Pathways Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Long-term potentiation, Neuroactive ligand-receptor interaction, Systemic lupus erythematosus
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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