NMDAR2A (GRIN2A) Rabbit Polyclonal Antibody
Rabbit Polyclonal anti-GRIN2A Antibody
Product Datasheet for 'TA890121'
|Recommend Dilution||WB: 1:500~2000|
|Reactivity||Human, Mouse, Rat|
|Immunogen||Recombinant protein of human GRIN2A|
|Formulation||PBS with 0.02% sodium azide, 50% glycerol, pH7.3|
|Purification||Purified from Rabbit serum by antigen affinity chromatography|
|Predicted Protein Size||165.28 kDa|
|Gene Name||glutamate ionotropic receptor NMDA type subunit 2A|
|Background||This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]|
|Synonyms||EPND; FESD; GluN2A; LKS; NMDAR2A; NR2A|
|Protein Families||Druggable Genome, Ion Channels: Glutamate Receptors, Ion Channels: Sodium, Transmembrane|
|Protein Pathways||Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Long-term potentiation, Neuroactive ligand-receptor interaction, Systemic lupus erythematosus|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.