MYBPC3 Mouse Monoclonal Antibody [Clone ID: OTI9E4]
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Purified recombinant protein of Homo sapiens myosin binding protein C, cardiac (MYBPC3), 20 µg
USD 867.00
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Specifications
Product Data | |
Clone Name | |
Applications | ELISA |
Recommended Dilution | ELISA 1:5000-10000 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human MYBPC3(C0-C1) (NP_000247) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Predicted Protein Size | 140.8 kDa |
Gene Name | myosin binding protein C, cardiac |
Database Link | |
Background | MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008] |
Synonyms | CMD1MM; CMH4; cMyBP-C; FHC; LVNC10; MYBP-C |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM) |
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