FOLR2 Mouse Monoclonal Antibody [Clone ID: OTI4G6]

CAT#: TA808026

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FOLR2 mouse monoclonal antibody, clone OTI4G6 (formerly 4G6)



  View other "OTI4G6" antibodies (4)

USD 478.00


Availability*
In Stock

Size
    • 100 ul


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Specifications

Product Data
Clone Name OTI4G6
Applications IHC, WB
Recommended Dilution WB 1:500, IHC 1:150
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 20-221 of human FOLR2(NP_000794) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 29.1 kDa
Gene Name folate receptor beta
Background The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms BETA-HFR; FBP; FBP/PL-1; FR-BETA; FR-P3
Reference Data
Protein Families Druggable Genome, Secreted Protein

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