DR5 (TNFRSF10B) Mouse Monoclonal Antibody [Clone ID: OTI1B9]
CAT#: TA807279
TNFRSF10B mouse monoclonal antibody, clone OTI1B9 (formerly 1B9)
Size: 30 ul
Formulation: Carrier-Free
USD 867.00
USD 436.00
Specifications
Product Data | |
Clone Name | OTI1B9 |
Applications | IHC, WB |
Recommended Dilution | IHC 1:150 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 203-411 of human TNFRSF10B(NP_671716) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 39.4 kDa |
Gene Name | tumor necrosis factor receptor superfamily member 10b |
Database Link | |
Background | The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009] |
Synonyms | CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Apoptosis, Cytokine-cytokine receptor interaction, Natural killer cell mediated cytotoxicity, p53 signaling pathway |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF807279 | Carrier-free (BSA/glycerol-free) TNFRSF10B mouse monoclonal antibody, clone OTI1B9 (formerly 1B9) |
USD 600.00 |
|
TA807279AM | TNFRSF10B mouse monoclonal antibody, clone OTI1B9 (formerly 1B9), Biotinylated |
USD 509.00 |
|
TA807279BM | TNFRSF10B mouse monoclonal antibody, clone OTI1B9 (formerly 1B9), HRP conjugated |
USD 509.00 |
|
TA807279S | TNFRSF10B mouse monoclonal antibody, clone OTI1B9 (formerly 1B9) |
USD 200.00 |
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