NR2C2 Mouse Monoclonal Antibody [Clone ID: OTI2H2]

CAT#: TA807271S

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NR2C2 mouse monoclonal antibody, clone OTI2H2 (formerly 2H2)



Special Offer: Get this sample size at $99/€99. Use code "TrueSample".

USD 200.00


Availability*
2 Days

Size
    • 30 ul


Specifications

Product Data
Clone Name OTI2H2
Applications IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150
Reactivities Human, Mouse, Rat
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 1-241 of human NR2C2(NP_003289) produced in E.coli.
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 67.2 kDa
Gene Name nuclear receptor subfamily 2 group C member 2
Background This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]
Synonyms TAK1; TR4
Reference Data
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
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