MMP2 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI4A11]
MMP2 mouse monoclonal antibody, clone OTI4A11 (formerly 4A11), HRP conjugated
View other "OTI4A11" antibodies (4)
Specifications
Product Data | |
Clone Name | OTI4A11 |
Applications | IHC, WB |
Recommended Dilution | WB 1:2000, IHC 1:150 |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 228-507 of human MMP2(NP_004521) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | HRP |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 70.9 kDa |
Gene Name | matrix metallopeptidase 2 |
Database Link | |
Background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Synonyms | CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 |
Reference Data | |
Protein Families | Druggable Genome, Protease |
Protein Pathways | Bladder cancer, GnRH signaling pathway, Leukocyte transendothelial migration, Pathways in cancer |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF806846 | Carrier-free (BSA/glycerol-free) MMP2 mouse monoclonal antibody, clone OTI4A11 (formerly 4A11) |
USD 545.00 |
|
TA806846 | MMP2 mouse monoclonal antibody, clone OTI4A11 (formerly 4A11) |
USD 417.00 |
|
TA806846AM | MMP2 mouse monoclonal antibody, clone OTI4A11 (formerly 4A11), Biotinylated |
USD 462.00 |
|
TA806846S | MMP2 mouse monoclonal antibody, clone OTI4A11 (formerly 4A11) |
USD 186.00 |
USD 186.00